The Developmental Origins of Endometriosis

NCT05951452 · ctgov completed
Enrollment
40
Start
2024-01-08
Completion
2026-06-17
Last updated
2026-06-18
Has results
False
Countries
France

Conditions

Endometriosis

Tagged with

endometriosis

Interventions

Eligibility criteria
Inclusion Criteria: * Nulliparous woman * No hormonal contraception for at least 3 months * Regular menstrual cycles (between 26 and 32 days) or proven ovulation (positive urine ovulation test ovulation test or progesterone level \>3 ng/ml in the luteal phase) * Normal BMI (≥ 18,5 and \< 30 kg/m²) Specific criteria (ENDO+ group) : * Stage III or IV endometriosis confirmed by laparoscopy or by laparotomy or MRI * Painful symptoms Specific criteria (ENDO- group) : • Patient without endometriosis confirmed by laparoscopy Exclusion Criteria: * Ovarian stimulation planned within 3 months * Adenomyosis * Use of a copper coil * Polycystic ovary syndrome * Pudendal neuralgia * Episiotomy or lesion of the posterior perineum that may modify AGD * Diabetes or thyroid disease * Chronic liver failure, chronic renal failure, cardiac pathology, autoimmune disease * Autism * Diagnosis and/or treatment for psychiatric illness * Chronic exposure to cocaine, methamphetamine, morphine or ecstasy within 30 days before the inclusion visit * Chronic exposure to Tetrahydrocannabinol (THC) within 7 days prior to inclusion. * Patient on treatment(s) that vary oxytocin (e.g. atosiban), testosterone or GnRH * Pregnant or breast-feeding patient * Patients who have given birth or breastfed within 6 weeks before the inclusion visit * Patient unable to read French * Failure to obtain informed consent * Patient not affiliated with or not benefiting from a national health insurance scheme * Person under legal protection, guardianship or curatorship * Patient participating in other research involving the human person
License: public-domain-us · commercial use OK · attribution required
Courtesy of ClinicalTrials.gov / U.S. National Library of Medicine

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