Enantiomeric Excess Dependent Splitting of NMR Signal Through Co-Ligand Dynamic Exchange in a Coordination Complex

A coordination complex ( L ·2Zn·3 C ), where L is a prochiral ligand and C is an exchangeable acetate co-ligand, exhibits symmetrical splitting of 1 H-NMR resonances due to L , which is proportional to the enantiomeric excess ( ee ) of a chiral guest co-ligand, 2-phenoxypropionic acid ( PPA ). The NMR resonances remain split even in dilute solution due to the high stability of complex with chiral guest.