Feel so bac: is Fusobacterium the suspect causing endometriosis?
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Fusobacterium nucleatum was detected in women with endometriosis and found to induce macrophage infiltration, TGF-β production, and lesion development in mouse models.
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Abstract
Recent work by Muraoka and colleagues reports that the Gram-negative anaerobic bacterium Fusobacterium nucleatum is detected in the uterus of 64% of women with endometriosis. Fusobacterium infection causes macrophage infiltration, transforming growth factor-β production, and transgelin upregulation in human and mouse endometria as well as endometriotic lesion development in a mouse model of endometriosis.
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Source provenance
- europepmc
- last seen: 2026-06-04T01:30:01.192114+00:00
- pubmed
- last seen: 2026-05-29T00:33:26.437191+00:00
- unpaywall
- last seen: 2026-05-14T19:30:52.867331+00:00
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Courtesy of the U.S. National Library of Medicine
Courtesy of the U.S. National Library of Medicine