The Expression of eNOS and iNOS in the Glangualar Epithelium of Ectopic Endometrium in Women with Dysmenorrhoea Secondary to Endometriosis

Objective To study the function of NO/NOS in dysmenorrhoea,we investigated the expression of eNOS and iNOS in the glandualar epithelium of ectopic endometrium from women with dysmenorrhoea secondary to endometriosis during the menstrual cycle. Methods Immunohistochemical SP methods were used identification the expression of eNOS and iNOS monoclonal antibody in ectopic endometrium from 36 women with dysmenorrhoea and 34 women without dysmenorrhoea. Results No significant difference was observed in the expression of eNOS in ectopic endometrium glandular epithelia between women with and without dysmenorrhoea.The expression of iNOS in the women with dysmenorrhoea had persistently higher expression than those in the women without dysmenorrhoea during the menstrual cycle.Conclusion These findings suggest NO/NOS maybe relevant to the pathogenesis of dysmenorrhoea secondary to endometriosis.