Endometrioid adenocarcinoma arising in adenomyosis – difficulties in diagnostics

Endometrial carcinoma is the most prevalent cancer of the female genital organs with an estimated number of 10.700 new cases in Germany each year. The uterine adenomyosis is a very common benign change, defined as ectopic endometrial gland and stroma cells located in the uterine myometrium. While endometrial carcinoma presents as malignant transformation of the intracavitary layer, there are only rare cases reported, in which endometrial carcinoma raised from adenoymosis.