Comparison of Clinical Features Between Patients with Positive and Negative Appendectomy

Objective: The objective of this study was to retrospectively compare clinical features and prognostic values between the patients who were referred to the general surgery clinic of our hospital with the presumed diagnosis of acute appendicitis and underwent positive or negative appendectomy. Methods: : Patients were divided into two groups as positive (PA) (n:425) and negative appendectomy (NA) (n:425) and the data obtained were compared between these two groups. Laboratory investigations were performed in all patients, and white blood cell (WBC), mean platelet volume (MPV), neutrophils count (NEU), neutrophils (%) (NEU%), C-reactive protein (CRP) and total bilirubin (TBIL) values were studied. Results: : The mean MPV value was found as 7.66 in PA groups and 7.90 in NA group, and the mean MPV value was statistically significantly lower in PA group, compared to NA groups (p=0.034). The mean TBIL value was 0.75 in PA group and 0.90 in NA group, and the mean TBIL value was statistically significantly lower in PA group (p=0.034).There was no statistically significant difference between the two groups in terms of the other studied laboratory parameters (for all p>0.05). Conclusion: The mean MPV and TBIL values can be used as specific biomarkers in predicting positive acute appendicitis. We believe that these results will contribute to the literature and will be guiding for future studies.