Adaptability, solubility and biocompatibility of TheraCal LC compared with MTA-Angelus and Biodentine as a furcation perforation repair material

Abstract Background: This study evaluated the adaptability, solubility and biocompatibility of TheraCal LC compared with mineral trioxide aggregate (MTA-Angelus) and Biodentine when used as a furcation perforation repair material. Methods: The adaptability was assessed by scanning electronic microscope (SEM) and presence of any gap between the dentin surface and filing material in each quadrant of the sample was analyzed at 1000 X magnification. The solubility was measured after one week by the ISO standard method. Biocompatibility was assessed by the inflammatory response and radiography after one and three months of repair of experimental furcation perforations in dog's teeth. Results: There were significant differences in the adaptability, solubility and biocompatibility of the tested materials (P <0.05). TheraCal LC showed the highest frequency distribution of gap presence that was followed by MTA-Angelus then Biodentine. The least soluble material after one week was TheraCal LC that was followed by MTA-Angelus and Biodentine. After one and three months, TheraCal LC showed the highest inflammatory response and highest frequency distribution of radiolucency that was followed by Biodentine then MTA-Angelus. Conclusion: Unlike Biodentine, the TheraCal LC is incapable of alternating MTA in the furcation perforation repair due to its poor biocompatibility and poor marginal adaptation.