Clinical Significance of Determination of Changes of Serum Adiponectin and Hs-CRP Levels After Treatmentin Patients with Endometriosis
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In 46 endometriosis patients, pretreatment serum adiponectin levels were significantly lower and high-sensitivity C-reactive protein levels higher than in controls, with both markers normalizing after three months of therapy.
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Abstract
Objective To explore the clinical significance of changes of serum adiponectin and Hs-CRP levels after treatment in patients with endometriosis.Methods Concentrations of resistin were determined by enzyme linked immunosorbent assay(ELISA),and Hs-CRP was determined by rate nephelometry immunoassay.Serum adiponectin and Hs-CRP levels were determined in 46 patients with endometriosis both before and after treatment as well as in 34 controls.Results Before treatment,the serum Hs-CRP levels in patients were significantly higher than those in the controls(P<0.01).while the adiponectin levels were significantly lower(P<0.01).After 3 months of treatment all the levels were not significantly different from those in controls(P>0.05).Conclusion Development of endometriosis were closely related to the serum levels of adiponectin and Hs-CRP.
Key words:
Endometriosis; Adiponectin; High-sensitive C-reactive Protein(Hs-CRP)
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- last seen: 2026-06-10T17:14:06.276822+00:00
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