Clinical Significance of Determination of Changes of Serum Adiponectin and Hs-CRP Levels After Treatmentin Patients with Endometriosis

In: Zhongguo linchuang shiyong yixue · 2009 · vol. 3(10) , pp. 24–25 · doi:10.3760/cma.j.issn1673-8799.2009.10.12 · W3030300308
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In 46 endometriosis patients, pretreatment serum adiponectin levels were significantly lower and high-sensitivity C-reactive protein levels higher than in controls, with both markers normalizing after three months of therapy.

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Abstract

Objective To explore the clinical significance of changes of serum adiponectin and Hs-CRP levels after treatment in patients with endometriosis.Methods Concentrations of resistin were determined by enzyme linked immunosorbent assay(ELISA),and Hs-CRP was determined by rate nephelometry immunoassay.Serum adiponectin and Hs-CRP levels were determined in 46 patients with endometriosis both before and after treatment as well as in 34 controls.Results Before treatment,the serum Hs-CRP levels in patients were significantly higher than those in the controls(P<0.01).while the adiponectin levels were significantly lower(P<0.01).After 3 months of treatment all the levels were not significantly different from those in controls(P>0.05).Conclusion Development of endometriosis were closely related to the serum levels of adiponectin and Hs-CRP. Key words: Endometriosis; Adiponectin; High-sensitive C-reactive Protein(Hs-CRP)

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endometriosis

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