Incidence and factors associated with hemodynamic change At Post Anesthesia Care Unit among adult surgical patients At Wachemo University Nigest Elleni Mohammed Memorial Comprehensive Specialized Hospital, 2023: Ethiopia, A prospective Observational study | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Research Article Incidence and factors associated with hemodynamic change At Post Anesthesia Care Unit among adult surgical patients At Wachemo University Nigest Elleni Mohammed Memorial Comprehensive Specialized Hospital, 2023: Ethiopia, A prospective Observational study Yisehak Wolde¹, Sintayehu Samuel¹, Teketel Abebe¹ This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-4959888/v1 This work is licensed under a CC BY 4.0 License Status: Published Journal Publication published 20 Dec, 2024 Read the published version in BMC Anesthesiology → Version 1 posted 4 You are reading this latest preprint version Abstract Background : Hemodynamic change, which is an independent risk factor of long-term patient morbidity and duration of stay in the hospital, is a risk for patients in the post-anaesthesia care unit. Multiple predictors contribute to the development of postoperative hemodynamic instability. Prevention and treatment of these factors may minimize patients’ hemodynamic instability, and its associated morbidity and mortality. Objective : This study aimed to determine the incidence and factors associated with hemodynamic change among adult surgical patients in the postanesthesia care unit. Method : An institution-based observational study was conducted from December 1, 2023, to June 30, 2024. And 409 adult surgery patients had participated. We employed consecutive sampling technique and both analytical and descriptive statistics to explain our findings. Using both bi-variable and multi-variable logistic regression, we evaluated the strength of the association and determined the crude odds ratio and adjusted odds ratio with a 95% confidence interval. A p-value of less than 0.05 is considered statistically significant in multi variable regression. Result : The total incidence of hemodynamic instability was 53.8.47% (CI: 0.45, 0.64). The incidence of hypotension, hypertension, tachycardia and bradycardia was 24.2%, 17.45%, 31.3%, and 12.6% respectively. ASA class III, procedures longer than 4 intraoperative hemodynamic instability and regional anaesthesia were significantly associated with hemodynamic instability in the postanaesthetic care unit. Conclusion : In general, the incidence of hemodynamic instability was a significant finding. The intraoperative HDI, ASA class III, postoperative respiratory adverse events, neurologic and gynaecological procedures, use of regional anaesthesia, and prolonged duration of procedures were predictors of hemodynamic instability in the post-anesthesia care unit. Certainly, it is desirable to adopt prediction tools in surgical patients, when the risk of postoperative complications is high, so staffing and medical resources of a particular clinical setup should be considered. Developing risk prediction tools is not enough, but it can be used as a baseline source to develop evidence-based clinical pathways. Implementing and evaluating the adopted clinical pathway to improve the quality of postoperative care. Hemodynamic change post-anaesthetic care unit surgical patients Figures Figure 1 Figure 2 Full Text Additional Declarations No competing interests reported. Tables 1 to 5 are available in the Supplementary Files section. Supplementary Files tablelegendpacu1.docx Cite Share Download PDF Status: Published Journal Publication published 20 Dec, 2024 Read the published version in BMC Anesthesiology → Version 1 posted Editorial decision: Revision requested 30 Aug, 2024 Editor assigned by journal 29 Aug, 2024 Submission checks completed at journal 28 Aug, 2024 First submitted to journal 22 Aug, 2024 You are reading this latest preprint version Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. As a division of Research Square Company, we’re committed to making research communication faster, fairer, and more useful. We do this by developing innovative software and high quality services for the global research community. Our growing team is made up of researchers and industry professionals working together to solve the most critical problems facing scientific publishing. Also discoverable on Platform About Our Team In Review Editorial Policies Advisory Board Help Center Resources Author Services Accessibility API Access RSS feed Manage Cookie Preferences © Research Square 2026 | ISSN 2693-5015 (online) Privacy Policy Terms of Service Do Not Sell My Personal Information {"props":{"pageProps":{"initialData":{"identity":"rs-4959888","acceptedTermsAndConditions":true,"allowDirectSubmit":false,"archivedVersions":[],"articleType":"Research Article","associatedPublications":[],"authors":[{"id":347236311,"identity":"dd814309-978e-4b42-b3d4-4cc9c970dba9","order_by":0,"name":"Yisehak 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