Iodolopyrazolium Salts – Synthesis, Derivatizations and Applications
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Abstract
A fast and reliable synthesis of pyrazole-substituted iodolium triflates is described. Their versatile application as useful synthetic intermediates for straight-forward modifications of pharmaceuticals is demonstrated using Celecoxib as model substrate. Finally, their application as potent halogen-bond donors in a Ritter-type reaction is shown.
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- europepmc
- last seen: 2026-05-19T01:45:01.086888+00:00