Nabothian Cyst

Nabothian cysts, also known as mucinous retention cysts or epithelial cysts, are a common and benign gynecological condition in reproductive-aged females. These cysts form at the squamocolumnar junction of the uterine cervix, the targeted area for sampling during cervical screening cytology. These cysts are typically filled with mucus but may also contain proteinaceous material, neutrophils, or neutrophilic debris. Nabothian cysts usually appear superficially and are easily recognized during colposcopic examination. Multiple and large Nabothian cysts located in the cervical stroma can cause significant cervical enlargement, potentially leading to symptoms. Other causes of large cervical cysts include cystic degeneration of uterine leiomyomas, congenital uterine cysts such as mesonephric and paramesonephric cysts, and cystic adenomyosis.