The therapeutic effect of percutaneous microwave ablation in treatment of focal uterine adenomyosis

In: Chin J Med Ultrasound(Electronic Edition) · 2017 · vol. 14(4) , pp. 314–318 · doi:10.3877/cma.j.issn.1672-6448.2017.04.016 · W3029905517
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AI-generated summary by claude@2026-07, 2026-07-09

Percutaneous microwave ablation effectively treated focal uterine adenomyosis, with contrast-enhanced ultrasound and DCE-MRI showing over 90% ablation rates and high consistency between modalities.

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The paper studied percutaneous microwave ablation for 42 patients with single focal uterine adenomyosis, using contrast-enhanced ultrasound and dynamic contrast-enhanced MRI (DCE-MRI) performed before and 1–2 days after treatment to evaluate ablation effects. After ablation, both imaging methods showed no enhancement in the ablated zones, with mean ablation volumes around 49 cm3 and mean ablation rates of about 92% or higher; the authors report similar concordance between contrast-enhanced ultrasound and DCE-MRI for ablation rate assessment. The major limitation explicitly implied by the design is the short post-procedure imaging window (imaging only 1–2 days after ablation), without longer-term outcomes described. This paper is centrally about adenomyosis — it assesses how contrast-enhanced ultrasound measures treatment ablation rate for focal uterine adenomyosis after percutaneous microwave ablation, with DCE-MRI comparison.

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Abstract

Objective To observe and analyze the therapeutic effect of focal uterine adenomyosis treated with percutaneous microwave ablation by contrast-enhanced ultrasound and dynamic contrast enhanced MRI (DCE-MRI). Methods From January 2013 to July 2016, 42 patients with focal uterine adenomyosis voluntarily underwent percutaneous microwave ablation in the tumor hospital of Liaocheng. Contrast-enhanced ultrasound and DCE-MRI were performed before and after percutaneous microwave ablation. The therapeutic effects of percutaneous microwave ablation in treatment of uterine adenomyosis lesions were observed. Results After percutaneous microwave ablation of the 42 cases, the ablated zone showed no enhancement with contrast-enhanced ultrasound and DCE-MRI. Contrast-enhanced ultrasound showed that the volume and ablation rate of ablated zone were (49.0±29.5) cm3 and (91.6±7.1)%, and that of DCE-MRI were (49.4±29.9)cm3 and (91.9±6.7)%, respectively. The results showed that percutaneous microwave ablation could cure focal uterine adenomyosis at the rate over 90%. Contrast-enhanced ultrasound and DCE-MRI are in accordance in observing the ablation rate. Conclusions Contrast-enhanced ultrasound can accurately show the ablation rate of focal uterine adenomyosis treated with percutaneous microwave ablation, which is quite consistent with DCE-MRI. Contrast-enhanced ultrasound has its advantages such as identifying the lesions which need immiedately supplemental ablation. Key words: Ultrasonography; Contrast medium; Magnetic resonance imaging; Uterine adenomyosis; Microwave ablation
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Objective

To observe and analyze the therapeutic effect of focal uterine adenomyosis treated with percutaneous microwave ablation by contrast-enhanced ultrasound and dynamic contrast enhanced MRI (DCE-MRI).

Methods

From January 2013 to July 2016, 42 patients with focal uterine adenomyosis voluntarily underwent percutaneous microwave ablation in the tumor hospital of Liaocheng. Contrast-enhanced ultrasound and DCE-MRI were performed before and after percutaneous microwave ablation. The therapeutic effects of percutaneous microwave ablation in treatment of uterine adenomyosis lesions were observed.

Results

After percutaneous microwave ablation of the 42 cases, the ablated zone showed no enhancement with contrast-enhanced ultrasound and DCE-MRI. Contrast-enhanced ultrasound showed that the volume and ablation rate of ablated zone were (49.0±29.5) cm3 and (91.6±7.1)%, and that of DCE-MRI were (49.4±29.9)cm3 and (91.9±6.7)%, respectively. The results showed that percutaneous microwave ablation could cure focal uterine adenomyosis at the rate over 90%. Contrast-enhanced ultrasound and DCE-MRI are in accordance in observing the ablation rate.

Conclusions

Contrast-enhanced ultrasound can accurately show the ablation rate of focal uterine adenomyosis treated with percutaneous microwave ablation, which is quite consistent with DCE-MRI. Contrast-enhanced ultrasound has its advantages such as identifying the lesions which need immiedately supplemental ablation. | [1] | 张晶,冯蕾,张冰松, 等. 经皮微波凝固子宫肌瘤效果研究 [J/CD]. 中华医学超声杂志(电子版), 2011, 8(1):84-92. | | [2] | 张晶,冯蕾,张冰松, 等. 超声引导经皮子宫肌瘤微波消融后随访研究 [J]. 中华医学杂志, 2011, 91(1):48-50. | | [3] | 卢峻,余志红,熊奕, 等. 超声造影在子宫腺肌症和子宫肌瘤鉴别诊断中的应用 [J]. 临床超声医学杂志, 2011, 13(3):166-168. | | [4] | 翟栋材,张申杰,张博, 等. 超声造影与增强MRI评价聚焦超声消融治疗子宫腺肌症的对照研究 [J]. 山东大学学报(医学版), 2014, 52(S1):112-113. | | [5] | 王芳,张晶,韩治宇, 等. 超声造影在经皮微波消融子宫肌层良性病变围手术期中的作用 [J/CD]. 中华医学超声杂志(电子版), 2012, 9(1):52-56. | | [6] | Champaneria R, Abedin P, Daniels J, et al. Ultrasound scan and magnetic resonance imaging for the diagnosis of adenomyosis: systematic review comparing test accuracy [J]. Acta Obstet Gynecol Scand, 2010, 89(11):1374-1384. | | [7] | Yang Q, Zhang LH, Su J, et al. The utility of diffusion-weighted MR imaging in differentiation of uterine adenomyosis and leiomyoma [J]. Eur J Radiol, 2011, 79(2):e47-e51. | | [8] | Lei F, Jing Z, Bo W, et al. Uterine myomas treated with microwave ablation: the agreement between ablation volumes obtained from contrast-enhanced sonography and enhanced MRI [J]. Int J Hyperthermia, 2014, 30(1):11-18. | | [9] | Atzori E. Sonography for the diagnosis of adenomyosis [J]. Ultrasound Obstet Gynecol, 2003, 21(6):626-627. | | [10] | Reinhold C, Tafazoli F, Mehio A, et al. Uterine adenomyosis: endovaginal US and MR imaging features with histopathologic correlation [J]. Radiographics, 1999, 19 Spec No:S147-S160. | | [11] | 卢增新,王伯胤,赵振华, 等. KMG和PVA经子宫动脉栓塞治疗子宫肌瘤术后不良反应的对照研究 [J]. 现代中西医结合杂志, 2006, 15(9):1151-1152. | | [12] | 张晶,关铮,钱林学, 等. 超声引导经皮微波消融治疗子宫肌瘤临床应用的指南建议 [J/CD]. 中华医学超声杂志(电子版), 2015, 12(5):353-356. | | [1] | 章建全, 程杰, 陈红琼, 闫磊. 采用ACR-TIRADS评估甲状腺消融区的调查研究[J/OL]. 中华医学超声杂志(电子版), 2024, 21(10): 966-971. | | [2] | 罗辉, 方晔. 品管圈在提高甲状腺结节细针穿刺检出率中的应用[J/OL]. 中华医学超声杂志(电子版), 2024, 21(10): 972-977. | | [3] | 杨忠, 时敬业, 邓学东, 姜纬, 殷林亮, 潘琦, 梁泓, 马建芳, 王珍奇, 张俊, 董姗姗. 产前超声在胎儿22q11.2 微缺失综合征中的应用价值[J/OL]. 中华医学超声杂志(电子版), 2024, 21(09): 852-858. | | [4] | 孙佳丽, 金琳, 沈崔琴, 陈晴晴, 林艳萍, 李朝军, 徐栋. 机器人辅助超声引导下经皮穿刺的体外实验研究[J/OL]. 中华医学超声杂志(电子版), 2024, 21(09): 884-889. | | [5] | 宋勇, 李东炫, 王翔, 李锐. 基于数据挖掘法分析3 种超声造影剂不良反应信号[J/OL]. 中华医学超声杂志(电子版), 2024, 21(09): 890-898. | | [6] | 史学兵, 谢迎东, 谢霓, 徐超丽, 杨斌, 孙帼. 声辐射力弹性成像对不可切除肝细胞癌门静脉癌栓患者放射治疗效果的评价[J/OL]. 中华医学超声杂志(电子版), 2024, 21(08): 778-784. | | [7] | 李洋, 蔡金玉, 党晓智, 常婉英, 巨艳, 高毅, 宋宏萍. 基于深度学习的乳腺超声应变弹性图像生成模型的应用研究[J/OL]. 中华医学超声杂志(电子版), 2024, 21(06): 563-570. | | [8] | 洪玮, 叶细容, 刘枝红, 杨银凤, 吕志红. 超声影像组学联合临床病理特征预测乳腺癌新辅助化疗完全病理缓解的价值[J/OL]. 中华医学超声杂志(电子版), 2024, 21(06): 571-579. | | [9] | 刘晨鹭, 刘洁, 张帆, 严彩英, 陈倩, 陈双庆. 增强MRI 影像组学特征生境分析在预测乳腺癌HER-2 表达状态中的应用[J/OL]. 中华乳腺病杂志(电子版), 2024, 18(06): 339-345. | | [10] | 钱警语, 郑明明. 《2024意大利妇产科学会非侵入性和侵入性产前诊断指南》解读[J/OL]. 中华妇幼临床医学杂志(电子版), 2024, 20(05): 486-492. | | [11] | 陈意志. 核磁共振钆造影剂导致的肾源性系统性纤维化[J/OL]. 中华肾病研究电子杂志, 2024, 13(06): 358-358. | | [12] | 杜霞, 马梦青, 曹长春. 造影剂诱导的急性肾损伤的发病机制及干预靶点研究进展[J/OL]. 中华肾病研究电子杂志, 2024, 13(05): 279-282. | | [13] | 张琛, 秦鸣, 董娟, 陈玉龙. 超声检查对儿童肠扭转缺血性改变的诊断价值[J/OL]. 中华消化病与影像杂志(电子版), 2024, 14(06): 565-568. | | [14] | 张立俊, 孙存杰, 胡春峰, 孟冲, 张辉. MSCT、DCE-MRI 评估术前胃癌TNM 分期的准确性研究[J/OL]. 中华消化病与影像杂志(电子版), 2024, 14(06): 519-523. | | [15] | 韦巧玲, 黄妍, 赵昌, 宋庆峰, 陈祖毅, 黄莹, 蒙嫦, 黄靖. 肝癌微波消融术后中重度疼痛风险预测列线图模型构建及验证[J/OL]. 中华临床医师杂志(电子版), 2024, 18(08): 715-721. | | 阅读次数 | ||||| | 全文 | | |||| | 摘要 | | |||| 版权所有 中华医学会 中华医学电子音像出版社有限责任公司 京ICP备14006079号-1 网络出版服务许可证:(署)网出证(京)字第075号 AI 小 编 AI小编

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