Primary Non Hodgkin'ss Lymphoma of the Vagina

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Abstract

The genital tract as a primary site of malignant lymphoma in women is extremely rare. This report concerns a 64 year old patient with a primary vaginal non-Hodgkin lymphoma (large cell B lineage according to the REAL classification--centroblastic type according to the Kiel classification--"G" according Working Formulation) with an unusual clinical presentation--pelvic discomfort accompanied by frequent ureteral-like colic. Due to gynecological onset symptoms and the rarity of this extranodal primary site misinterpretation of a primary vaginal lymphoma as a benign inflammatory disease or endometriosis may occur. We emphasize the importance of their recognition and also the differential diagnosis of cervical lymphoma from other neoplastic and non-neoplastic lesions.

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Condition tags

chronic_pelvic_painendometriosis

MeSH descriptors

Lymphoma, Large B-Cell, Diffuse Pelvic Pain Vaginal Neoplasms Abdominal Pain Abdominal Pain Diagnosis, Differential Female Hemorrhage Hemorrhage Humans Lymphoma, Large B-Cell, Diffuse Lymphoma, Large B-Cell, Diffuse Lymphoma, Large B-Cell, Diffuse Middle Aged Pelvic Inflammatory Disease Pelvic Inflammatory Disease Pelvic Inflammatory Disease Pelvic Pain Ureteral Obstruction Ureteral Obstruction

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References (23)

Source provenance

europepmc
last seen: 2026-06-17T06:13:18.893374+00:00
openalex
last seen: 2026-06-04T00:00:01.174412+00:00
pubmed
last seen: 2026-05-13T22:10:24.024533+00:00
License: CC0 · commercial use OK