Clinical Study Abnormal Expression of Prostaglandins E2 and F2
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This study quantified prostaglandin E2 and F2 receptor mRNA expression in eutopic and ectopic endometrium from women with endometriosis compared to controls.
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Abstract
Copyright © 2015 Halima Rakhila et al.This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Objective. To investigate the level of expression of prostaglandin receptivity and uptake factors in eutopic and ectopic endometrium of women with endometriosis.Design. Prospective study. Setting.Human reproduction research laboratory. Patients. Seventy-eight patients with endometriosis and thirty healthy control subjects. Intervention(s). Endometrial and endometriotic tissue samples were obtained during laparoscopic surgery. Main Outcome Measure(s). Real-time polymerase chain reaction assay of mRNA encoding prostaglandin E2 receptors (EP1, EP2, EP3, and EP4), prostaglandin F2
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