Measurements of the Corpus Callosum in epileptic patients Using Magnetic Resonance Imaging

Abstract Background and Purpose: In recent years, magnetic resonance imaging (MRI) has been used to evaluate seizures in patients with epilepsy. The Corpus callosum (CC) serves as a crucial communication structure between the two brain hemispheres, making it valuable to study MRI changes in patients with epilepsy. This study aimed to measure the CC in patients with epilepsy and report any structural differences. Materials and Methods: We conducted a cross-sectional study involving 150 patients diagnosed with epilepsy. T2W MRI mid-sagittal cuts were taken to measure the length and width of the middle third of the CC. Results: The mean length of the CC was 6.89 ± 0.59 cm, while the mean width of the middle third of the CC was 3.23 ± 1.3 mm. Significant correlations were found between CC measurements and factors such as the number of drugs used, drug resistance, refractory epilepsy (RE), and the presence of MRI lesions. Conclusion: The results demonstrate that epilepsy affects the CC, and there is likely a correlation between CC width, the number of drugs used, drug resistance, and the presence of primary lesions in MRI. These findings can contribute to further studies on prognostic factors in epilepsy.