Analysis Of Dose At 3D-Crt And Imrt Techniques In Left Breast Cancer Case With Hypofractionation Using Deep Inspiration Breath-Hold (Dibh)

Analysis Of Dose At 3D-Crt And Imrt Techniques In Left Breast Cancer Case With Hypofractionation Using Deep Inspiration Breath-Hold (Dibh) | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Help Center Sign In Submit a Preprint Cite Share Download PDF Research Article Analysis Of Dose At 3D-Crt And Imrt Techniques In Left Breast Cancer Case With Hypofractionation Using Deep Inspiration Breath-Hold (Dibh) Samsun - -, Muhammad Arif Arif, Gregorius Septayudha Septayudha This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-779184/v1 This work is licensed under a CC BY 4.0 License Status: Posted Version 1 posted You are reading this latest preprint version Abstract In terms of breast cancer radiation treatment, it has radiation using the 3D-Conformal Radiotherapy (3D-CRT) technique and the continuation of the 3D-CRT technique, namely the Intensity Modulated Radiation Therapy (IMRT) technique. This study aims to evaluate the dosage aspects of PTV and OAR between the 3D-CRT and IMRT techniques in cases of left breast cancer with hypofractionation using the Deep Inspiration Breath Hold (DIBH) method using the Conformity Index (CI) and Homogeneity Index (H.I.) and H.I. organ at risk uses tolerance limits. This type of research is comparative quantitative with ten samples with primary data conducted at Siloam T.B. Hospital. Simatupang from November 2019 to April 2020. The research was carried out in the form of radiation planning with 3D-CRT techniques and IMRT techniques, and the results of planning both techniques were evaluated between 3D-CRT techniques and IMRT techniques through PTV evaluations using CI and H.I. values. Furthermore, the organs at risk use tolerance limits on each organ. The results showed the assessment between 3D-CRT and IMRT on PTV and organs at risk received different doses. The PTV shows the CI value, which is almost the same as the difference of 0.034, and there is a slight difference in H.I. with an average value in the IMRT technique of 0.07 and 3D-CRT of 0.11, and it can be seen that the IMRT is slightly superior because the excellent H.I. value is the closest to 0. Then at the dose of organ at risk received by the sample, the 3D-CRT technique is slightly superior by obtaining a lower dose that obtains the difference in the heart by 0.53%, lung by 3.46%, spinal cord by 6.51 Gy, esophagus at 4.5 Gy, and larynx at 5.18 Gy. Oncology Medical Physics Breast Cancer 3D-CRT IMRT Organ At Risk CI and H.I. Full Text Cite Share Download PDF Status: Posted Version 1 posted You are reading this latest preprint version Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. 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Also discoverable on Platform About Our Team In Review Editorial Policies Help Center Resources Author Services Accessibility API Access RSS feed Manage Cookie Preferences © Research Square 2026 | ISSN 2693-5015 (online) Privacy Policy Terms of Service Do Not Sell My Personal Information {"props":{"pageProps":{"initialData":{"identity":"rs-779184","acceptedTermsAndConditions":true,"allowDirectSubmit":true,"archivedVersions":[],"articleType":"Research Article","associatedPublications":[],"authors":[{"id":43980418,"identity":"ba37ff02-4273-475d-8fb9-d27eca71ba4c","order_by":0,"name":"Samsun - -","email":"data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAZAAAAAyAQMAAABI0h/eAAAABlBMVEX///8AAABVwtN+AAAACXBIWXMAAA7EAAAOxAGVKw4bAAAA90lEQVRIiWNgGAWjYDACZjApUc/PzNj+4QMDQwKxWmwSJNubjzHOIEoLBKQlGJw5lsbMQ4wW/nbuxM8FDIfzGG7kmD22bbPL42dvYPzwMQe3FonDvJulZzAcLmackWNunNuWXCzZc4BZcuY2PNYc5t0gzcNwmLFZIsdAOreNOXHDjQQ2Zl48WuSBtvwGaWkDabFsqyesxeAw7zagLWmJPTzH0qQZ2w4T1mII1GLNw2BjLMHefNiw59zxxJk9B5vx+kXu/NnNt3kYJOTsDzM2PvhRVp3Yz9588MNHfN4HAcZ/MAYbmGwgoB4F/CFF8SgYBaNgFIwUAABRKVFmDwZb4AAAAABJRU5ErkJggg==","orcid":"https://orcid.org/0000-0002-0722-4563","institution":"Politeknik Kementerian Kesehatan Jakarta II","correspondingAuthor":true,"submittingAuthor":false,"prefix":"","firstName":"Samsun","middleName":"-","lastName":"-","suffix":""},{"id":43980419,"identity":"1d52bef4-1b3b-4b46-94ff-a9a7c84ddac8","order_by":1,"name":"Muhammad Arif Arif","email":"","orcid":"","institution":"University of Indonesia: Universitas Indonesia","correspondingAuthor":false,"submittingAuthor":false,"prefix":"","firstName":"Muhammad","middleName":"Arif","lastName":"Arif","suffix":""},{"id":43980420,"identity":"f346c3ee-a4ea-467f-bb86-09074b6dd944","order_by":2,"name":"Gregorius Septayudha Septayudha","email":"","orcid":"","institution":"RSU UKI: Rumah Sakit Umum Universitas Kristen Indonesia","correspondingAuthor":false,"submittingAuthor":false,"prefix":"","firstName":"Gregorius","middleName":"Septayudha","lastName":"Septayudha","suffix":""}],"badges":[],"createdAt":"2021-08-04 10:35:34","currentVersionCode":1,"declarations":"","doi":"10.21203/rs.3.rs-779184/v1","doiUrl":"https://doi.org/10.21203/rs.3.rs-779184/v1","draftVersion":[],"editorialEvents":[],"editorialNote":"","failedWorkflow":false,"files":[],"financialInterests":"","formattedTitle":"\u003cp\u003eAnalysis Of Dose At 3D-Crt And Imrt Techniques In Left Breast Cancer Case With Hypofractionation Using Deep Inspiration Breath-Hold (Dibh)\u003c/p\u003e","fulltext":[{"header":"Full Text","content":"This preprint is available for \u003ca href='/article/rs-779184/latest.pdf' target='_blank'\u003edownload as a PDF\u003c/a\u003e."}],"fulltextSource":"","fullText":"","funders":[],"hasAdminPriorityOnWorkflow":false,"hasManuscriptDocX":false,"hasOptedInToPreprint":true,"hasPassedJournalQc":"","hasAnyPriority":true,"hideJournal":true,"highlight":"","institution":"","isAcceptedByJournal":false,"isAuthorSuppliedPdf":true,"isDeskRejected":"","isHiddenFromSearch":false,"isInQc":false,"isInWorkflow":false,"isPdf":false,"isPdfUpToDate":true,"isWithdrawnOrRetracted":false,"journal":{"display":true,"email":"[email protected]","identity":"researchsquare","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":true,"externalIdentity":"","sideBox":"","snPcode":"","submissionUrl":"/submission","title":"Research Square","twitterHandle":"researchsquare","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"","reportingPortfolio":"","inReviewEnabled":false,"inReviewRevisionsEnabled":true},"keywords":"Breast Cancer, 3D-CRT, IMRT, Organ At Risk, CI and H.I.","lastPublishedDoi":"10.21203/rs.3.rs-779184/v1","lastPublishedDoiUrl":"https://doi.org/10.21203/rs.3.rs-779184/v1","license":{"name":"CC BY 4.0","url":"https://creativecommons.org/licenses/by/4.0/"},"manuscriptAbstract":"\u003cp\u003eIn terms of breast cancer radiation treatment, it has radiation using the 3D-Conformal Radiotherapy (3D-CRT) technique and the continuation of the 3D-CRT technique, namely the Intensity Modulated Radiation Therapy (IMRT) technique. This study aims to evaluate the dosage aspects of PTV and OAR between the 3D-CRT and IMRT techniques in cases of left breast cancer with hypofractionation using the Deep Inspiration Breath Hold (DIBH) method using the Conformity Index (CI) and Homogeneity Index (H.I.) and H.I. organ at risk uses tolerance limits.\u0026nbsp;\u003c/p\u003e\u003cp\u003eThis type of research is comparative quantitative with ten samples with primary data conducted at Siloam T.B. Hospital. Simatupang from November 2019 to April 2020. The research was carried out in the form of radiation planning with 3D-CRT techniques and IMRT techniques, and the results of planning both techniques were evaluated between 3D-CRT techniques and IMRT techniques through PTV evaluations using CI and H.I. values. Furthermore, the organs at risk use tolerance limits on each organ.\u0026nbsp;\u003c/p\u003e\u003cp\u003eThe results showed the assessment between 3D-CRT and IMRT on PTV and organs at risk received different doses. The PTV shows the CI value, which is almost the same as the difference of 0.034, and there is a slight difference in H.I. with an average value in the IMRT technique of 0.07 and 3D-CRT of 0.11, and it can be seen that the IMRT is slightly superior because the excellent H.I. value is the closest to 0. 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