Diagnostic method
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This invention identifies eight polymorphisms in the human flt-1 gene to develop diagnostic methods for angiogenic diseases, including endometriosis.
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Abstract
This invention relates to novel sequence and polymorphisms in the human flt-1 gene. Eight specific polymorphisms are identified. The invention also relates to methods and materials for analysing allelic variation in the flt-1 gene and to the use of flt-1 polymorphism in the diagnosis and treatment of angiogenic diseases and cancer. Diseases associated with pathological angiogenesis include diabetic retinopathies, psoriasis, rheumatoid arthritis and endometriosis.
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- europepmc
- last seen: 2026-10-30T06:09:08.764285+00:00