Evaluation of Preoperative and Postoperative Endometrial/Uterine Histopathology Results in Patients with Uterine Prolapse

Aim: The aim of the study was to compare the preoperative and postoperative endometrial histopathologic findings and to detect the unexpected malignancies among the asymptomatic women with endometrial thickness below 5 mm, who underwent vaginal hysterectomy for POP. Material and Methods: A total of forty-eight female patients between January 2010 and December 2016 were included in this retrospective cross-sectional study. Pap Smear and endometrial biopsy were performed to all patients before surgery. Also, the endometrial wall thickness of all patients was evaluated by ultrasonography preoperatively. The histopathological data of 48 vaginal hysterectomy patients operated for pelvic organ prolapse were analyzed. Results: The preoperative endometrial biopsy results were observed as atrophic endometrium and proliferative endometrium in 70.8% and 29.2% rates, respectively. The postoperative histopathologic results were found as endometrial cystic atrophy, proliferative endometrium and endometrial polyp in 60.4%, 14% and 25% rates, respectively. In addition, leiomyoma and adenomyosis were determined after hysterectomy in 37.5% and 16.7%, respectively. Conclusion: Our results showed that endometrial sampling is not primarily necessary for asymptomatic uterovaginal prolapse patients if endometrial thickness is less than 5mm. It has been concluded that preoperative evaluation of endometrial thickness by transvaginal ultrasound would be sufficient in patients with these conditions.