Management of Chronic Pancreatitis with Pancreatic Duct Calculi

Gupta S, Sukriti Gupta, Sudhatri CR, Cholleti Raja Sudhatri, Athavale V, Virendra Athavale, Shreya Nagula Reddy, Reddy SN, Nithin N, Nayani Nithin
Annals of African medicine · 2026 · vol. 25(Suppl 1) , pp. S118–S121 · doi:10.4103/aam.aam_654_25 · PMID:41575227 · PMC13541312
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This case report describes successful surgical management of chronic pancreatitis with pancreatic duct calculi in a postpartum woman using the Partington-Rochelle procedure, resulting in complete symptom resolution.

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⚙ AI-generated deep summary by qwen3.7-flash, 2026-09-02 · read from full text ⓘ

This case report describes a 37-year-old postpartum female presenting with chronic calcific pancreatitis, characterized by irreversible fibrosis and multiple large calculi within the main pancreatic duct. Despite conservative management failing to alleviate her worsening epigastric pain and nausea, she underwent a lateral pancreaticojejunostomy with intraoperative extraction of the ductal stones. The patient experienced an uneventful recovery and complete resolution of symptoms at six-week follow-up, highlighting the efficacy of surgical intervention for ductal obstruction in this context. This paper does not explicitly discuss endometriosis or adenomyosis; it was included in the corpus via a keyword match in the upstream search index.

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Abstract

Chronic pancreatitis (CP) is a progressive inflammatory disorder of the pancreas characterized by irreversible fibrosis and intraductal calculi, leading to recurrent abdominal pain and functional impairment. Here, we present the case of a 37-year-old female, 2 months postpartum with a history of gestational diabetes, who presented with 1 month of worsening epigastric pain radiating to the back, aggravated after meals, and associated with nausea and nonbilious vomiting. Laboratory investigations were unremarkable except for mildly elevated HbA1c, while imaging revealed multiple large calculi within the main pancreatic duct, confirming chronic calcific pancreatitis. Conservative management failed to relieve symptoms, necessitating surgical intervention. She underwent lateral pancreaticojejunostomy (Partington-Rochelle procedure) with intraoperative extraction of ductal calculi. Postoperative recovery was uneventful, and at 6-week follow-up, she reported complete resolution of symptoms with improved quality of life. This case emphasizes the importance of timely diagnosis and surgical management in CP with ductal obstruction.
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Management of Chronic Pancreatitis with Pancreatic Duct Calculi - Sukriti Gupta - Cholleti Raja Sudhatri, - Virendra Athavale - Shreya Nagula Reddy - Nayani Nithin Chronic pancreatitis (CP) is a progressive inflammatory disorder of the pancreas characterized by irreversible fibrosis and intraductal calculi, leading to recurrent abdominal pain and functional impairment. Here, we present the case of a 37-year-old female, 2 months postpartum with a history of gestational diabetes, who presented with 1 month of worsening epigastric pain radiating to the back, aggravated after meals, and associated with nausea and nonbilious vomiting. Laboratory investigations were unremarkable except for mildly elevated HbA1c, while imaging revealed multiple large calculi within the main pancreatic duct, confirming chronic calcific pancreatitis. Conservative management failed to relieve symptoms, necessitating surgical intervention. She underwent lateral pancreaticojejunostomy (Partington–Rochelle procedure) with intraoperative extraction of ductal calculi. Postoperative recovery was uneventful, and at 6-week follow-up, she reported complete resolution of symptoms with improved quality of life. This case emphasizes the importance of timely diagnosis and surgical management in CP with ductal obstruction.

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MeSH descriptors

Calculi Calculi Calculi Calculi Calculi Pancreatic Ducts Pancreatic Ducts Pancreatic Ducts Pancreatic Ducts Pancreaticojejunostomy Pancreaticojejunostomy Pancreatitis, Chronic Pancreatitis, Chronic Pancreatitis, Chronic Pancreatitis, Chronic Abdominal Pain Abdominal Pain Adult Female Humans

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europepmc
last seen: 2026-10-04T09:26:46.659050+00:00
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