Method for the therapeutic management of endometriosis

2006
OA: closed
AI-generated summary by qwen3.7-flash, 2026-09-09

This invention describes a therapeutic method for managing endometriosis symptoms, including extrauterine tissue proliferation and pelvic pain, using short-term LH-RH antagonist treatment followed by contraceptives, anti-inflammatory agents, or androgens.

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Abstract

The present inventions provides a method for therapeutic management of extrauterine proliferation of endometrial tissue, chronic pelvic pain and fallopian tube obstruction by short term induction treatment with an LH-RH antagonist for 4 to 12 weeks. According to another aspect of the present invention, the short term LH-RH treatment is followed by the combined or separate administration of one or more active agents selected from the group consisting of a contraceptive, preferably an oral contraceptive, a non-steroidal anti-rheumatic agent, an analgetic, an androgen other than a 17-alpha-alkyl substituted testosterone or any combinations thereof.According to a further aspect of the present invention a pharmaceutical composition comprising an LHRH antagonist and one ore more active agents selected from the group consisting of a contraceptive, preferably an oral contraceptive, a non-steroidal anti-rheumatic agent, an analgetic, an androgen other than a 17-alpha-alkyl substituted testosterone or any combinations thereof are provided.

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europepmc
last seen: 2026-07-25T06:15:30.875455+00:00