Endometrioid Adenocarcinoma of the Endometrium: Postoperative Debulking and Pelvic/Abdominal Wall Recurrence—A Case Report

This case describes a young woman with a history of endometrioid endometrial adenocarcinoma treated with robotic hysterectomy and bilateral salpingo oophorectomy with pelvic lymph nodes sampling, who later developed pelvic and abdominal wall metastases. The patient’s main concerns centered on recurrence and treatment options. Initial pathology showed a low-grade endometrioid tumor confined to the endometrium with shallow myometrial invasion and negative nodes. Subsequent surveillance revealed suspicious pelvic lymph nodes and a new abdominal wall metastasis confirmed by IR biopsy (CK7+, PAX-8+, ER+, CK20−, GATA-3−, TTF-1−, WT p53). Management evolved to systemic chemotherapy with immunotherapy, with plans for radiotherapy or possible surgical intervention based on response; the takeaway is early tissue confirmation guiding multidisciplinary, multimodal therapy in recurrent gynecologic cancer.