A True Labor Test: Cervical Length and Fetal Fibronectin to Differentiate True from False Labor at Term Gestation

A True Labor Test: Cervical Length and Fetal Fibronectin to Differentiate True from False Labor at Term Gestation | Authorea try { document.documentElement.classList.add('js'); } catch (e) { } var _gaq = _gaq || []; _gaq.push(['_setAccount', 'G-8VDV14Y67G']); _gaq.push(['_trackPageview']); (function() { var ga = document.createElement('script'); ga.type = 'text/javascript'; ga.async = true; ga.src = ('https:' == document.location.protocol ? 'https://ssl' : 'http://www') + '.google-analytics.com/ga.js'; var s = document.getElementsByTagName('script')[0]; s.parentNode.insertBefore(ga, s); })(); Skip to main content Preprints Collections Wiley Open Research IET Open Research Ecological Society of Japan All Collections About About Authorea FAQs Contact Us Quick Search anywhere Search for preprint articles, keywords, etc. Search Search ADVANCED SEARCH SCROLL This is a preprint and has not been peer reviewed. Data may be preliminary. 23 January 2026 V1 Latest version Share on A True Labor Test: Cervical Length and Fetal Fibronectin to Differentiate True from False Labor at Term Gestation Authors : Puntabut Warintaksa 0000-0002-7946-3774 , Chanakan Youkhong , Metha TrikasemmartMD , Rakruthai Thongchai , Suwatcharaporn Hadradchai , and Piya Chaemsaithong [email protected] Authors Info & Affiliations https://doi.org/10.22541/au.176915363.35207301/v1 107 views 53 downloads Contents Abstract Supplementary Material Information & Authors Metrics & Citations View Options References Figures Tables Media Share Abstract Objectives: To determine the predictive performance of 1) cervical length, 2) cervicovaginal fluid fetal fibronectin, and 3) maternal angiogenic factors concentration for the identification of spontaneous true onset of labor at term in patients presenting with labor symptoms. Design: A prospective cohort study Setting: Labor and Delivery unit, Bangkok, Thailand Population: 146 singleton pregnancies with symptoms of labor Methods: Cervical length, cervicovaginal fluid fetal fibronectin, and angiogenic factors were measured. Main Outcome Measures: The primary outcome was the spontaneous onset of true labor at term, followed by delivery within 24 hours. Predictive performance of individual biomarkers and the combined model was calculated to identify the spontaneous onset of true labor at term. Results: The combination of cervical length and fetal fibronectin yielded significantly better predictive performance than the individual markers, with a sensitivity of 62.1%, a specificity of 90.6%, a positive predictive value of 92.3%, and a positive likelihood ratio of 6.62 for the identification of spontaneous true-onset labor at term. Conclusion: Cervical length measurement with fetal fibronectin had a high specificity, positive predictive value, and positive likelihood ratio for identifying the spontaneous true onset of labor at term. This test may be used as a bedside test to rule in the diagnosis of true labor in patients presenting with labor symptoms at term. Funding: Supported by the Faculty of Medicine, Ramathibodi Hospital, to Puntabut Warintaksa. This study received “Pol. Gen. Dr. Jongjate Aojanepong Fund” of the Royal Thai College of Obstetricians and Gynecologists (RTCOG) to Puntabut Warintaksa, Piya Chaemsaithong. Supplementary Material File (manuscripts false labor bjog 22jan2026.docx) Download 177.34 KB File (tables 6jan2026.docx) Download 23.91 KB Information & Authors Information Version history V1 Version 1 23 January 2026 Copyright This work is licensed under a Non Exclusive No Reuse License. Keywords delivery: perineal care diagnostic studies general obstetrics labour: management maternal physiology Authors Affiliations Puntabut Warintaksa 0000-0002-7946-3774 Mahidol University Faculty of Medicine Ramathibodi Hospital View all articles by this author Chanakan Youkhong Mahidol University Faculty of Medicine Ramathibodi Hospital View all articles by this author Metha TrikasemmartMD Mahidol University Faculty of Medicine Ramathibodi Hospital View all articles by this author Rakruthai Thongchai Mahidol University Faculty of Medicine Ramathibodi Hospital View all articles by this author Suwatcharaporn Hadradchai Mahidol University Faculty of Medicine Ramathibodi Hospital View all articles by this author Piya Chaemsaithong [email protected] Mahidol University Faculty of Medicine Ramathibodi Hospital View all articles by this author Metrics & Citations Metrics Article Usage 107 views 53 downloads .FvxKWukQNSOunydq8rnd { width: 100px; } Citations Download citation Puntabut Warintaksa, Chanakan Youkhong, Metha TrikasemmartMD, et al. A True Labor Test: Cervical Length and Fetal Fibronectin to Differentiate True from False Labor at Term Gestation. Authorea . 23 January 2026. DOI: https://doi.org/10.22541/au.176915363.35207301/v1 If you have the appropriate software installed, you can download article citation data to the citation manager of your choice. Simply select your manager software from the list below and click Download. For more information or tips please see 'Downloading to a citation manager' in the Help menu . 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