Gamete intrafallopian transfer by hysteroscopy as an alternative treatment for infertility

G. L. Possati, Possati G, G Possati, R Seracchioli, Renato Seracchioli, C Melega, Melega C, A Pareschi, ANNA PARESCHI, Pareschi A, Andrea Maccolini, A Maccolini, Maccolini A, C Flamigni, Flamigni C
Fertility and Sterility · 1991 · vol. 56(3) , pp. 496–499 · doi:10.1016/s0015-0282(16)54547-6 · PMID:1894028 · W2413372445
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This paper describes hysteroscopic gamete intrafallopian transfer as an alternative infertility treatment.

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Abstract

ObjectiveTo evaluate efficacy and safety of the hysteroscopic cannulation by flexible catheter of the fallopian tubes for gamete intrafallopian transfer (GIFT).DesignWe studied the pregnancy rate (PR) and the safety of this new technique.SettingAll patients were enlisted for GIFT at our Reproductive Medicine Unit.PatientsWe treated 26 patients whose infertility causes were terminal tubal damage, male factors, unexplained factors, and endometriosis. Patients with uterine tubal ostia unsuitable for gamete transfer or cervical incontinence were not included in the group.InterventionsThe patients underwent ovulation induction and oocyte retrieval by transvaginal ultrasonically guided puncture. The gamete transfers were carried out by hysteroscopic procedure using a flexible catheter put through the operating channel.Main outcome measureThe efficacy was evaluated by the PR (25.9%).ResultsSeven clinical pregnancies were obtained, but two patients aborted during the first weeks of pregnancy. No ectopic pregnancies were observed.ConclusionsOur results indicate that hysteroscopic GIFT is an alternative, safe, effective, and not invasive technique for fertility problems.

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Condition tags

infertility

MeSH descriptors

Gamete Intrafallopian Transfer Hysteroscopy Infertility Adult Evaluation Studies as Topic Female Gamete Intrafallopian Transfer Humans Infertility Pregnancy Pregnancy Outcome

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