Bone mineral loss during lactation and recovery after weaning

Heidi J. Kalkwarf; Bonny Specker

doi:10.1016/0029-7844(95)00083-4

Bone mineral loss during lactation and recovery after weaning

Heidi J. Kalkwarf, Bonny Specker

In: Obstetrics & Gynecology · 1995 · vol. 86(1) , pp. 26–32 · doi:10.1016/0029-7844(95)00083-4 · PMID:7784018 · W2025319068

article OA: closed CC0 ⤵ 1 in-corpus citation

View on OpenAlex View on PubMed View at publisher

Abstract

OBJECTIVE: To test the hypothesis that bone mineral content (BMC) and density (BMD) are lost during lactation and regained within 6 months after weaning. METHODS: Two cohorts of women, defined by time postpartum, were enrolled into the study; each cohort was followed for 6 months. Women in the lactation cohort (65 lactating women and 48 nonlactating postpartum controls) were enrolled at 2 weeks postpartum. Women in the weaning cohort (40 lactating and 43 nonlactating postpartum controls) were enrolled at 4-6 months postpartum. Lactating women enrolled in the weaning cohort had been fully breast-feeding at enrollment and weaned within 2 months of enrollment. Bone mineral content of the total body and BMD of the lumbar spine and distal radius were measured by dual-energy x-ray absorptiometry. RESULTS: Lactating women lost significantly more bone in the total body (-2.8 versus -1.7%) and lumbar spine (-3.9 versus 1.5%) than did nonlactating women during the first 6 months postpartum. There was no effect of lactation on bone changes at the distal radius. After weaning, lactating women gained significantly more bone in the lumbar spine than did nonlactating women (5.5 versus 1.8%). Earlier resumption of menses was associated with a smaller loss of bone during lactation and a greater increase of bone after weaning. CONCLUSION: Women lose bone during lactation but gain bone after weaning. Thus, lactation may not result in net bone loss.

My notes (saved in your browser only)

Citation neighborhood (sparse)

Too few in-corpus citations on either side for a chart; here are the lists.

Cites (1)

REVERSIBLE TRABECULAR BONE DENSITY LOSS FOLLOWING INDUCED HYPO‐OESTROGENISM WITH THE GnRH ANALOGUE BUSERELIN IN PREMENOPAUSAL WOMEN 1988

Cited by (1)

Long-Acting Progestin Injectables 2006

References (25)

REVERSIBLE TRABECULAR BONE DENSITY LOSS FOLLOWING INDUCED HYPO‐OESTROGENISM WITH THE GnRH ANALOGUE BUSERELIN IN PREMENOPAUSAL WOMEN via openalex
doi:10.1016/s0015-0282(16)60782-3 via openalex
doi:10.1111/j.1365-2265.1982.tb01597.x via openalex
doi:10.1016/0002-9343(85)90468-1 via openalex
doi:10.1111/j.1365-2265.1992.tb02350.x via openalex
doi:10.1073/pnas.86.18.7183 via openalex
doi:10.1093/ajcn/48.6.1479 via openalex
doi:10.1002/9781118032923 via openalex
W128531299 via openalex
doi:10.1093/ije/22.4.684 via openalex
doi:10.1210/jcem-70-1-83 via openalex
doi:10.1093/oxfordjournals.aje.a114716 via openalex
doi:10.1093/ajcn/36.3.431 via openalex
W2414729618 via openalex
doi:10.1016/s0025-6196(12)62164-8 via openalex
doi:10.1016/0306-9877(91)90276-5 via openalex
doi:10.1016/0002-9343(91)80156-g via openalex
doi:10.1093/oxfordjournals.aje.a113987 via openalex
doi:10.1093/oxfordjournals.aje.a114384 via openalex
doi:10.1001/jama.1993.03500240074029 via openalex
doi:10.1016/s0002-9378(88)80075-9 via openalex
doi:10.1016/0002-9378(81)90327-6 via openalex
doi:10.1002/jbmr.5650050409 via openalex
doi:10.1210/jcem-67-4-701 via openalex
doi:10.1093/oxfordjournals.aje.a116570 via openalex

Cited by (1)

Long-Acting Progestin Injectables 2006

Source provenance

openalex: last seen: 2026-05-11T06:41:50.100108+00:00

License: CC0 · commercial use OK

[1] REVERSIBLE TRABECULAR BONE DENSITY LOSS FOLLOWING INDUCED HYPO‐OESTROGENISM WITH THE GnRH ANALOGUE BUSERELIN IN PREMENOPAUSAL WOMEN 1988