Influence of two hemostatic methods on ovarian reserve in young women with endometriotic cyst treated by laparoscopic cystectomy

Objective To investigate the influence on ovarian reserve for treatment of ovarian endometriotic cyst by laparoscopic cystectomy with two hemostatic methods in young women.Methods From Jan.2007 to Jan.2010,84 patients less than 35 year-old with single lateral ovarian endometriotic cyst in Yuyao People's Hospital,Zhejiang Province were divided into two groups randomly that 37 patients were in hemostatic suture group(A group)and 47 patients were in electric coagulation group(B group)during the operation.The basal sex hormone levels,amounts of basal antral follicles,peak systolic blood flow velocity(PSV)and basal ovarian volume were tested before the operation and on the third day in the first menstrual cycle after operation and the first menstrual cycle after 6 months operation.Clinic data were compared by self-control study and Contrastive Study.Results Compared with the data before operation,sex hormone including estradiol(E_2),follicle stimulating hormone(FSH),luteinizing hormone(LH)levels,FSH/LH ratio of A group at different time points after operation had no statistical significance(P0.05),but the data of B group at 6th month after operation were varied and had statistically significant(P0.05).The FSH values of B group was higher than that of the A group at different time points and the difference was statistically significant(P0.05).The differences of E_2 levels,FSH/LH ratio at the 6th month after operation were statistically significant between two groups(P0.05)while the differences of which on the 3rd day were no statistically significant(P0.05).The data of basal antral follicles,PSV,basal ovarian volume by transvaginal sonography of B group were declined more than than of A group at different time points after operation compared with those before operation that the difference was statistically significant(P0.05).The data of B group were declined more than A group,the difference was statistically significant(P0.05)between two groups.Conclusion Both of the two hemostatic methods in laparoscopic cystectomy for ovarian endometriotic cyst have effects on ovarian reserve,especially electro-coagulation hemostasis has more.