Inflammatory pseudotumor of the lung with high FDG uptake

Huellner MW, Martin W. Huellner, Bernhard Schwizer, Schwizer B, Irene Burger, Burger I, Ingo Fengels, Fengels I, Reinhard Schläpfer, Schläpfer R, Bussmann C, Christian Bussmann, Klaus Strobel, Strobel K
Clinical nuclear medicine · 2010 · doi:10.1097/RLU.0b013e3181ea33d0 · PMID:20706053
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A 23-year-old woman with hemoptysis presented with a high FDG-uptake lung lesion, ultimately diagnosed as an inflammatory myofibroblastic pseudotumor after lobectomy.

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This case report describes a 23-year-old woman presenting with recurrent hemoptysis and a lung mass that exhibited high fluorodeoxyglucose uptake on PET/CT imaging. The differential diagnosis for the lesion included infectious processes and various malignancies, notably listing endometriosis as a rare possibility alongside bronchial carcinoma and sarcoma. Definitive diagnosis was achieved only after lobectomy revealed an inflammatory myofibroblastic pseudotumor, highlighting the diagnostic challenge posed by the tumor's metabolic activity. Relevance to endometriosis: listed as one of several differential diagnoses for the lung mass, though the final confirmed pathology was an inflammatory pseudotumor rather than endometriosis.

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Abstract

We present the case of a 23-year-old woman with 2 episodes of hemoptysis. Computed tomography showed a small mass lesion with an adjacent cyst in the left lower lobe. On whole-body fluorodeoxyglucose positron emission tomography/computed tomography, the lesion had a high focal fluorodeoxyglucose-uptake (SUVmax 21.0). Differential diagnosis included tuberculosis, fungal infection, and tumors such as bronchial carcinoma, sarcoma, or rare entities like endometriosis. Bronchoscopy with transbronchial biopsies failed to deliver a conclusive diagnosis. Lobectomy was performed, and histopathology presented an inflammatory myofibroblastic pseudotumor.
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Interesting Image Inflammatory Pseudotumor of the Lung With High FDG Uptake - Martin W. Huellner - Bernhard Schwizer - Irene Burger - Ingo Fengels - Reinhard Schläpfer - Christian Bussmann - Klaus Strobel Abstract: We present the case of a 23-year-old woman with 2 episodes of hemoptysis. Computed tomography showed a small mass lesion with an adjacent cyst in the left lower lobe. On whole-body fluorodeoxyglucose positron emission tomography/computed tomography, the lesion had a high focal fluorodeoxyglucose-uptake (SUVmax 21.0). Differential diagnosis included tuberculosis, fungal infection, and tumors such as bronchial carcinoma, sarcoma, or rare entities like endometriosis. Bronchoscopy with transbronchial biopsies failed to deliver a conclusive diagnosis. Lobectomy was performed, and histopathology presented an inflammatory myofibroblastic pseudotumor. Copyright © 2010 Wolters Kluwer Health, Inc. All rights reserved.

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Condition tags

endometriosis

MeSH descriptors

Fluorodeoxyglucose F18 Granuloma, Plasma Cell Lung Diseases Positron-Emission Tomography Female Fluorodeoxyglucose F18 Granuloma, Plasma Cell Granuloma, Plasma Cell Humans Lung Diseases Lung Diseases Tomography, X-Ray Computed Young Adult

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pubmed
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