Available treatment methods for endometriosis

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This review outlines current pharmacological and surgical treatment methods for endometriosis, noting that while medications provide only symptomatic relief, surgery is required to remove lesions.

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This review article outlines the current diagnostic and therapeutic approaches for endometriosis, a chronic inflammatory condition affecting up to 15% of menstruating women. It identifies laparoscopy with histological examination as the gold standard for diagnosis while detailing various pharmacological agents, such as hormonal contraceptives and GnRH agonists, alongside surgical options including laparoscopic excision. The authors emphasize that medical management is primarily symptomatic rather than cytoreductive, necessitating surgical intervention to physically remove lesions, and stress the importance of tailoring treatment plans to individual patient preferences. This paper is centrally about endometriosis — specifically reviewing the spectrum of available pharmacological and surgical treatment methods for managing the disease.

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Abstract

Krupa Adrianna, Padała Olga, Putowski Maciej, Konopelko Michał, Piasek Ewa. Available treatment methods for endometriosis. Journal of Education, Health and Sport. 2019;9(7):178-184. eISSN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.3269215 http://ojs.ukw.edu.pl/index.php/johs/article/view/7119 https://pbn.nauka.gov.pl/sedno-webapp/works/917440 The journal has had 7 points in Ministry of Science and Higher Education parametric evaluation. Part B item 1223 (26/01/2017). 1223 Journal of Education, Health and Sport eISSN 2391-8306 7 © The Authors 2019; This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, Poland Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author (s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non commercial license Share alike. (http://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. The authors declare that there is no conflict of interests regarding the publication of this paper. Received: 20.06.2019. Revised: 25.06.2019. Accepted: 04.07.2019. Available treatment methods for endometriosis Adrianna Krupa, [email protected] ORCID:0000-0003-0866-3952 Department of Human Anatomy, Medical University of Lublin, Jaczewskiego 4 Street, 20-090 Lublin, Poland Olga Padała, [email protected] ORCID:0000-0003-1469-0877 1st Department of Psychiatry, Psychotherapy and Early Intervention Medical University of Lublin, Gluska Street 1, 20-439 Lublin, Poland Maciej Putowski, [email protected] ORCID:0000-0002-7575-2456 Department of Experimental Hematooncology, Medical University of Lublin, Chodźki 1 Street, 20-093 Lublin, Poland Michał Konopelko, [email protected] ORCID:0000-0003-4103-7400 Department of Otolaryngology and Laryngological Oncology, Medical University of Lublin, Jaczewskiego 8, 20-954, Lublin, Poland Ewa Piasek, [email protected], ORCID:0000-0003-3344-4022 I Clinic of Anaesthesiology and Intensive Therapy, Medical University of Lublin, Jaczewskiego 8, 20-954, Lublin, Poland KEY WORDS: endometriosis, treatment, pelvic pain, infertility ABSTRACT Introduction and and purpose of paper: The aim of this paper was to present modern methods of treatment for endometriosis. Endometriosis is a chronic inflammatory condition of women that is characterized by the implementation of endometrial tissue outside the uterus. It affects 7 to 15% of menstruating women, and 35 to 50% of women treated for infertility. State of knowledge: Diagnosis of endometriosis is made on the basis of well-collected gynecological history, clinical examinations and imaging techniques. The golden standard for diagnostics is laparoscopy with subsequent histological examination of the material collected during the procedure. Among the methods of treatment in women with endometriosis, pharmacological and surgical treatment is applied. The pharmacological agents most commonly used in endometriosis are: combined hormonal contraceptives, progestins and anti-progestins, GnRH agonists and antagonists, aromatase inhibitors, Danazol and non-steroidal anti-inflammatory drugs (NSAIDs). Pharmacological treatment is only symptomatic, not cytoreductive, therefore, to remove endometriosis lesions, surgery should be performed. There are two ways to perform surgery: laparotomy and laparoscopy. Surgical treatment of endometriosis may be associated with local excision of lesions and sometimes even removal of the entire organ. Treatment should be conducted in consultation with the patient and her wishes. Conservative treatment is most commonly used among women of reproductive age. Summary: The pharmaceutical or surgical treatment require an individual approach and deliberated informed consent of patient. Pharmacological treatment is only symptomatic, not cytoreductive, therefore, to remove endometriosis lesions, surgery should be performed.
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Available treatment methods for endometriosis Authors/Creators Description Krupa Adrianna, Padała Olga, Putowski Maciej, Konopelko Michał, Piasek Ewa. Available treatment methods for endometriosis. Journal of Education, Health and Sport. 2019;9(7):178-184. eISSN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.3269215 http://ojs.ukw.edu.pl/index.php/johs/article/view/7119 https://pbn.nauka.gov.pl/sedno-webapp/works/917440 The journal has had 7 points in Ministry of Science and Higher Education parametric evaluation. Part B item 1223 (26/01/2017). 1223 Journal of Education, Health and Sport eISSN 2391-8306 7 © The Authors 2019; This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, Poland Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author (s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non commercial license Share alike. (http://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. The authors declare that there is no conflict of interests regarding the publication of this paper. Received: 20.06.2019. Revised: 25.06.2019. Accepted: 04.07.2019. Available treatment methods for endometriosis Adrianna Krupa, [email protected] ORCID:0000-0003-0866-3952 Department of Human Anatomy, Medical University of Lublin, Jaczewskiego 4 Street, 20-090 Lublin, Poland Olga Padała, [email protected] ORCID:0000-0003-1469-0877 1st Department of Psychiatry, Psychotherapy and Early Intervention Medical University of Lublin, Gluska Street 1, 20-439 Lublin, Poland Maciej Putowski, [email protected] ORCID:0000-0002-7575-2456 Department of Experimental Hematooncology, Medical University of Lublin, Chodźki 1 Street, 20-093 Lublin, Poland Michał Konopelko, [email protected] ORCID:0000-0003-4103-7400 Department of Otolaryngology and Laryngological Oncology, Medical University of Lublin, Jaczewskiego 8, 20-954, Lublin, Poland Ewa Piasek, [email protected], ORCID:0000-0003-3344-4022 I Clinic of Anaesthesiology and Intensive Therapy, Medical University of Lublin, Jaczewskiego 8, 20-954, Lublin, Poland KEY WORDS: endometriosis, treatment, pelvic pain, infertility ABSTRACT Introduction and and purpose of paper: The aim of this paper was to present modern methods of treatment for endometriosis. Endometriosis is a chronic inflammatory condition of women that is characterized by the implementation of endometrial tissue outside the uterus. It affects 7 to 15% of menstruating women, and 35 to 50% of women treated for infertility. State of knowledge: Diagnosis of endometriosis is made on the basis of well-collected gynecological history, clinical examinations and imaging techniques. The golden standard for diagnostics is laparoscopy with subsequent histological examination of the material collected during the procedure. Among the methods of treatment in women with endometriosis, pharmacological and surgical treatment is applied. The pharmacological agents most commonly used in endometriosis are: combined hormonal contraceptives, progestins and anti-progestins, GnRH agonists and antagonists, aromatase inhibitors, Danazol and non-steroidal anti-inflammatory drugs (NSAIDs). Pharmacological treatment is only symptomatic, not cytoreductive, therefore, to remove endometriosis lesions, surgery should be performed. There are two ways to perform surgery: laparotomy and laparoscopy. Surgical treatment of endometriosis may be associated with local excision of lesions and sometimes even removal of the entire organ. Treatment should be conducted in consultation with the patient and her wishes. Conservative treatment is most commonly used among women of reproductive age. Summary: The pharmaceutical or surgical treatment require an individual approach and deliberated informed consent of patient. Pharmacological treatment is only symptomatic, not cytoreductive, therefore, to remove endometriosis lesions, surgery should be performed. Files 7119.pdf Files (123.3 kB) | Name | Size | Download all | |---|---|---| | md5:e0e7541b2411412517d4be63a0bf94ac | 123.3 kB | Preview Download |

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