Hysterectomy with opportunistic salpingectomy during the menopausal transition as a predictor of climacteric disorders

In: Journal of Education, Health and Sport · 2023 · vol. 47(1) , pp. 117–124 · doi:10.12775/jehs.2023.47.01.011 · W4387644607
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This study found that 46.25% of women experienced menopausal syndrome components 12 months after hysterectomy with opportunistic salpingectomy during menopause transition.

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This study assessed long-term consequences of hysterectomy with opportunistic salpingectomy performed during the menopausal transition in 160 reproductive-age women with hysterectomy for benign uterine pathology, using clinical and anamnestic data to identify risk factors. After 12 months, neurovegetative and psychoemotional manifestations of menopausal syndrome were reported in 46.25% of participants. The authors conclude that age over 45, hysterectomy, and hormonal therapy for benign uterine pathology were associated with metabolic disorders in the distant postoperative period, with combined effects increasing risk. This paper does not explicitly discuss endometriosis or adenomyosis; it was included in the corpus via a keyword match in the upstream search index.

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Abstract

Data on ovarian dysfunction after hysterectomy are found in literary sources, but the nature of changes in the hormonal profile, its chronological sequence, the issue of prognosis and possible preventive measures, even in the case of preservation of ovarian tissue, remain contradictory and fragmentary, which prompted the conduct of this research. The aim of the research is to assess the risk of menopausal disorders after hysterectomy with opportunistic salpingectomy during the menopausal transition. Research materials and methods.A comprehensive assessment of the long-term consequences of hysterectomy in 160 women of reproductive age was carried out. Risk factors were identified during a general clinical examination, based on anamnestic data. Indicators were evaluated in the examined women. Inclusion criteria: age of menopause transition, hysterectomy due to benign uterine pathology, patient's consent to participate in the study. Research results. The data obtained by us after 12 months from the moment of surgical intervention demonstrate neurovegetative and psychoemotional manifestations in 87 patients - 46.25%. Conclusions. 12 months after GE with opportunistic salpingectomy, 46.25% of patients have a gradual formation of components of the menopausal syndrome. age older than 45, hysterectomy, hormonal therapy of benign uterine pathology demonstrate a connection with the development of metabolic disorders in the distant postoperative period, and their combined effect increases the risk of their development.
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Hysterectomy with opportunistic salpingectomy during the menopausal transition as a predictor of climacteric disorders DOI: https://doi.org/10.12775/JEHS.2023.47.01.011Keywords uterine myoma, climacteric syndrome, hysterectomy, risk factors, hormone therapyAbstract Data on ovarian dysfunction after hysterectomy are found in literary sources, but the nature of changes in the hormonal profile, its chronological sequence, the issue of prognosis and possible preventive measures, even in the case of preservation of ovarian tissue, remain contradictory and fragmentary, which prompted the conduct of this research. The aim of the research is to assess the risk of menopausal disorders after hysterectomy with opportunistic salpingectomy during the menopausal transition. Research materials and methods.A comprehensive assessment of the long-term consequences of hysterectomy in 160 women of reproductive age was carried out. Risk factors were identified during a general clinical examination, based on anamnestic data. Indicators were evaluated in the examined women. Inclusion criteria: age of menopause transition, hysterectomy due to benign uterine pathology, patient's consent to participate in the study. Research results. The data obtained by us after 12 months from the moment of surgical intervention demonstrate neurovegetative and psychoemotional manifestations in 87 patients - 46.25%. Conclusions. 12 months after GE with opportunistic salpingectomy, 46.25% of patients have a gradual formation of components of the menopausal syndrome. age older than 45, hysterectomy, hormonal therapy of benign uterine pathology demonstrate a connection with the development of metabolic disorders in the distant postoperative period, and their combined effect increases the risk of their development. References Misura A. G. Dynamics of metabolic disorders after hysterectomy in the perimenopausal period. // Actual issues of pediatrics, obstetrics and gynecology. - 2014. - No. 2. - P.103-105. Read MD, Edey KA, Hapeshi J. et al. The age of ovarian failure following premenopausal hysterectomy with ovarian conservation // Menopause Int. 2010. V. 16, no. 2. P. 56–59; Nahás EAP, Pontes A., Nahas-Neto J. et al. Effect of Total Abdominal Hysterectomy on Ovarian Blood Supply in Women of Reproductive Age. J. Ultrasound. Med., 2005, vol. 24, pp. 169–174 Makris N., Vomvolaki E., Partsinevelos G. et al. The effect of hysterectomy on sexuality and psychological changes. The European Journal of Contraception and Reproductive Health Care March 2006;11(1):23–27; Dronova V.L. Psychological state of patients in the pre- and postoperative periods with gynecological and surgical pathology, methods of its determination (literature review) /V.I.Dronov, R.S.Teslyuk // Perinatology and pediatrics. 2017. - No. 1(69). - P.65-69. Laughlin-Tommaso SK, Khan Z, Weaver AL, et al. Cardiovascular and metabolic morbidity after hysterectomy with ovarian conservation: a cohort study. Menopause 2018;25:483–92.; S Bhattacharya, LJ Middleton, A Tsourapas, AJ Lee, R Champaneria, JP Daniels, T Roberts, NH Hilken, P Barton, R Gray, KS Khan, P Chien, P O'Donovan, KG Cooper; The International Heavy Menstrual Bleeding Individual Patient Data Meta-analysis Collaborative Group. Hysterectomy, endometrial ablation and Mirena® for heavy menstrual bleeding: a systematic review of clinical effectiveness and cost-effectiveness analysis. NIHR Journals Library; 2011 No. 15.19. Hehenkamp WJ, Volkers NA, Broekmans FJ, et al. Loss of ovarian reserve after uterine artery embolization: a randomized comparison with hysterectomy. Hum Reprod. 2007;22(7):1996-2005. doi:10.1093/humrep/dem105 Yuan Z, Cao D, Bi X, Yu M, Yang J, Shen K. The effects of hysterectomy with bilateral salpingectomy on ovarian reserve. Int J Gynaecol Obstet. 2019;145(2):233-238. doi:10.1002/ijgo.12798 Findley AD, Siedhoff MT, Hobbs KA, et al. Short-term effects of salpingectomy during laparoscopic hysterectomy on ovarian reserve: a pilot randomized controlled trial. Fertil Steril. 2013;100(6):1704-1708. doi:10.1016/j.fertnstert.2013.07.1997 Venturella R, Lico D, Borelli M, et al. 3 To 5 years later: long-term effects of prophylactic bilateral salpingectomy on ovarian function. J Minim Invasive Gynecol. 2017;24(1):145-150. doi:10.1016/j.jmig.2016.08.833 Vermeulen, CKM, Veen, J., Adang, C. et al. Long-term pelvic floor symptoms and urogenital prolapse after hysterectomy. BMC Women's Health 23, 115 (2023). https://doi.org/10.1186/s12905-023-02286-3 Altman D, Falconer C, Cnattingius S, Granath F. Pelvic organ prolapse surgery following hysterectomy on benign indications. Am J Obstet Gynecol. 2008;198(5):572.e1-572.e6. Peculiarities of assessing the quality of life and the search for ways of rehabilitation in women who have undergone surgery on the uterus / G. M. Havrylyuk, O. M. Makarchuk // Halytskyi doszni'nyi visnyk. - 2016. - Volume 23, Number 3(1). - P. 40-43. Mustafa A. Association between hysterectomy and hypertension among Indian middle-aged and older women: a cross-sectional study. BMJ Open. 2023 Apr 20;13(4):e070830. doi: 10.1136/bmjopen-2022-070830. Erratum in: BMJ Open. 2023 Jun 19;13(6):e070830corr1. PMID: 37080618; PMCID: PMC10124308. Matsuo K, Mandelbaum RS, Nusbaum DJ, Matsuzaki S, Klar M, Roman LD, Wright JD. National trends and outcomes of morbidly obese women who underwent inpatient hysterectomy for benign gynecological disease in the USA. Acta Obstet Gynecol Scand. 2021 Mar;100(3):459-470 Corrigan KE, Vargas MV, Robinson HN, Gu A, Wei C, Tyan P, Singh N, Tappy EE, Moawad GN. Impact of Diabetes Mellitus on Postoperative Complications Following Laparoscopic Hysterectomy for Benign Indications. Gynecol Obstet Invest. 2019;84(6):583-590. doi: 10.1159/000501034. Epub 2019 Jun 18. PMID: 31212286. Downloads Published How to Cite Issue Section License Copyright (c) 2023 Olha Proshchenko, Dmytro Govseev This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License. The periodical offers access to content in the Open Access system under the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 Stats Number of views and downloads: 517 Number of citations: 0

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