Medicinal composition and application thereof

The invention relates to a medicinal composition and application thereof. The composition comprises total alkaloids and total glycosides, wherein the total alkaloids are extracted from yanhusuo, and the total glycosides are extracted from peony the weight ratio of total yanhusuo alkaloids to total peony glycosides is 1:50-10:1, preferably 1:2.2-1:35.2, more preferably 1:2.2-1:17.6, most preferably 1:2.2-1:8.8, wherein the optimal weight ratio is 1:4.4. The medicinal composition, together with corresponding auxiliary materials, can be prepared into clinically acceptable pharmaceutical formulations, such as injections, powder injections, infusion solution, fat emulsions, pills, tablets, granules, oral liquid preparations, plaster or capsules. The medicinal composition can be used for preparing medicaments for treating gynecological diseases such as endometriosis, dysmenorrhea, abnormal menstruation and the like, can obviously reduce the volume of ectopic intima, has obvious curative effects on gynecological diseases such as endometriosis, dysmenorrhea, abnormal menstruation and the like, and has no toxic or side effect.