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Published November 3, 2025
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PATHOMORPHOLOGICAL ASPECTS OF DIFFUSE ADENOMYOSIS
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According to data from the World Health Organization, endometriosis affects approximately 10% (190 million) of women and girls of reproductive age worldwide, and its prevalence continues to rise. As a result, this condition is classified as a modern epidemic (WHO, 2022)
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References
- 1. Babajanova G.S., Abdurakhmonova S.I. (2018). Modern approaches to the diagnosis and treatment of combined uterine myoma and adenomyosis in women of reproductive age. 2. Ismoilova D.U., Musvakhodjayeva D., Magzumova N.M. Clinical and immunological criteria for the development of genital endometriosis in women and the basics of differential immunocorrection. In: Andreeva E., Moscow: Medicine, 2006. – 360 p. 3. Adamyan L.V., Andreeva E.N., Apolokhina I.A., Bezhenar V.F., Gevorkyan M.A., Gus A.I., Demidov V.N., Kalinina E.A., Levakov S.A., Marchenko L.A., Popov A.A., Sonova M.M., Khashukoeva A.Z., Chernukha G.E., Yarotskaya E.L. (2021). Endometriosis: Diagnosis, Treatment, and Rehabilitation. Moscow. – p. 65. 4. Kogan E.A., Kalinina E.A., Kolotovkina A.V., Faizullina N.M., Adamyan L.V. (2014). Morphological and molecular substrate of endometrial receptivity disorders in infertile patients with external genital endometriosis. Obstetrics and Gynecology, No. 8. 5. Nepomnyashchikh L.M., Lushnikova E.L., Pekarev O.G., Lushnikova A.K., Nikitenko E.V. (2012). Pathomorphological aspects of adenomyosis. Siberian Oncological Journal, No. 2(50), pp. 39–45. 6. Ordiyants I.M., Arakelov S.E., Kardanova V.V., Dmitrieva E.V., Ordiyants E.G. (2014). Prognostic significance of genetic factors in the development of uterine fibroids and their combination with adenomyosis. Mother and Child Journal of Kuzbass, No. 3(58), pp. 32–36. 7. Unanyan A.L., Sidorova I.S., Kogan E.A., Demura T.A., Demura S.A. (2013). Active and inactive adenomyosis: issues of pathogenesis and pathogenetic therapy. Obstetrics and Gynecology, No. 4. 8. Khilkevich E.G., Yazykova O.I. (2016). Hormonal therapy in the postoperative period in patients with endometriosis and uterine fibroids. Obstetrics and Gynecology, No. 10. 9. Bazot M., Cortez A., Darai E., Rouger J., Chopier J., Antoine J., Uzan S. (2001). Ultrasonography compared with magnetic resonance imaging for the diagnosis of adenomyosis: correlation with histopathology. Human Reproduction, Vol. 16, No. 11, pp. 2427–2433. 10. Bird C.C., McElin T.W., Manalo-Estrella P. (1972). The elusive adenomyosis of the uterus—revisited. American Journal of Obstetrics and Gynecology, No. 112, pp. 583–593
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