Reversible Mechanical Contraception and Endometriosis Treatment Using Stimuli‐Responsive Hydrogels (Adv. Mater. 23/2024)

In: Advanced Materials · 2024 · vol. 36(23) · doi:10.1002/adma.202470173 · W4399444274
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Stimuli-responsive hydrogel implants placed in fallopian tubes provide reversible contraception and mechanical prevention of endometriosis by blocking sperm and endometrial cells, with removal triggered by light.

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Abstract

Women's Health Reversible hydrogel implants for fallopian tube occlusion offer a potential solution for both reversible contraception and mechanical prevention of endometriosis. The soft hydrogel implant effectively blocks fallopian tubes, prevents sperm and endometrial cell crossing, and can be safely removed on demand by hysteroscopic light application. More details can be found in article number 2310301 by Alexandre H.C. Anthis, Inge K. Herrmann, and co-workers.
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Advanced Hub Main Navigation Menu Reversible Mechanical Contraception and Endometriosis Treatment Using Stimuli-Responsive Hydrogels (Adv. Mater. 23/2024) Alexandre H.C. Anthis Nanoparticle Systems Engineering Laboratory, Institute of Energy and Process Engineering (IEPE), Department of Mechanical and Process Engineering (D-MAVT), ETH Zurich, Sonneggstrasse 3, Zurich, 8092 Switzerland Particles Biology Interactions Laboratory, Department of Materials Meet Life, Swiss Federal Laboratories for Materials Science and Technology (Empa), Lerchenfeldstrasse 5, St. Gallen, 9014 Switzerland Ingenuity Laboratory, University Hospital Balgrist, Forchstrasse 340, Zurich, 8008 Switzerland Search for more papers by this authorSamuel Kilchenmann Nanoparticle Systems Engineering Laboratory, Institute of Energy and Process Engineering (IEPE), Department of Mechanical and Process Engineering (D-MAVT), ETH Zurich, Sonneggstrasse 3, Zurich, 8092 Switzerland Search for more papers by this authorManon Murdeu Particles Biology Interactions Laboratory, Department of Materials Meet Life, Swiss Federal Laboratories for Materials Science and Technology (Empa), Lerchenfeldstrasse 5, St. Gallen, 9014 Switzerland Search for more papers by this authorPaige J. LeValley Nanoparticle Systems Engineering Laboratory, Institute of Energy and Process Engineering (IEPE), Department of Mechanical and Process Engineering (D-MAVT), ETH Zurich, Sonneggstrasse 3, Zurich, 8092 Switzerland Particles Biology Interactions Laboratory, Department of Materials Meet Life, Swiss Federal Laboratories for Materials Science and Technology (Empa), Lerchenfeldstrasse 5, St. Gallen, 9014 Switzerland Search for more papers by this authorMorris Wolf Macromolecular Engineering Laboratory, Institute of Energy and Process Engineering (IEPE), Department of Mechanical and Process Engineering (D-MAVT), ETH Zurich, Sonneggstrasse 3, Zurich, 8092 Switzerland Search for more papers by this authorCharlotte Meyer Nanoparticle Systems Engineering Laboratory, Institute of Energy and Process Engineering (IEPE), Department of Mechanical and Process Engineering (D-MAVT), ETH Zurich, Sonneggstrasse 3, Zurich, 8092 Switzerland Particles Biology Interactions Laboratory, Department of Materials Meet Life, Swiss Federal Laboratories for Materials Science and Technology (Empa), Lerchenfeldstrasse 5, St. Gallen, 9014 Switzerland Search for more papers by this authorOscar Cipolato Nanoparticle Systems Engineering Laboratory, Institute of Energy and Process Engineering (IEPE), Department of Mechanical and Process Engineering (D-MAVT), ETH Zurich, Sonneggstrasse 3, Zurich, 8092 Switzerland Particles Biology Interactions Laboratory, Department of Materials Meet Life, Swiss Federal Laboratories for Materials Science and Technology (Empa), Lerchenfeldstrasse 5, St. Gallen, 9014 Switzerland Search for more papers by this authorMark W. Tibbitt Macromolecular Engineering Laboratory, Institute of Energy and Process Engineering (IEPE), Department of Mechanical and Process Engineering (D-MAVT), ETH Zurich, Sonneggstrasse 3, Zurich, 8092 Switzerland Search for more papers by this authorJachym Rosendorf Department of Surgery, Faculty of Medicine in Pilsen, Charles University, Alej Svobody 923/80, Pilsen, 32300 Czech Republic Biomedical Center, Faculty of Medicine in Pilsen, Charles University, Alej Svobody 1655/76, Pilsen, 32300 Czech Republic Search for more papers by this authorVaclav Liska Department of Surgery, Faculty of Medicine in Pilsen, Charles University, Alej Svobody 923/80, Pilsen, 32300 Czech Republic Biomedical Center, Faculty of Medicine in Pilsen, Charles University, Alej Svobody 1655/76, Pilsen, 32300 Czech Republic Search for more papers by this authorThomas Rduch Particles Biology Interactions Laboratory, Department of Materials Meet Life, Swiss Federal Laboratories for Materials Science and Technology (Empa), Lerchenfeldstrasse 5, St. Gallen, 9014 Switzerland Department of Gynecology and Obstetrics (Frauenklinik), Cantonal Hospital St. Gallen (KSSG), Rorschacherstrasse 95, St. Gallen, 9007 Switzerland Search for more papers by this authorInge K. Herrmann Nanoparticle Systems Engineering Laboratory, Institute of Energy and Process Engineering (IEPE), Department of Mechanical and Process Engineering (D-MAVT), ETH Zurich, Sonneggstrasse 3, Zurich, 8092 Switzerland Particles Biology Interactions Laboratory, Department of Materials Meet Life, Swiss Federal Laboratories for Materials Science and Technology (Empa), Lerchenfeldstrasse 5, St. Gallen, 9014 Switzerland Ingenuity Laboratory, University Hospital Balgrist, Forchstrasse 340, Zurich, 8008 Switzerland Faculty of Medicine, University of Zurich, Rämistrasse 71, Zurich, 8006 Switzerland Search for more papers by this authorAlexandre H.C. Anthis Nanoparticle Systems Engineering Laboratory, Institute of Energy and Process Engineering (IEPE), Department of Mechanical and Process Engineering (D-MAVT), ETH Zurich, Sonneggstrasse 3, Zurich, 8092 Switzerland Particles Biology Interactions Laboratory, Department of Materials Meet Life, Swiss Federal Laboratories for Materials Science and Technology (Empa), Lerchenfeldstrasse 5, St. Gallen, 9014 Switzerland Ingenuity Laboratory, University Hospital Balgrist, Forchstrasse 340, Zurich, 8008 Switzerland Search for more papers by this authorSamuel Kilchenmann Nanoparticle Systems Engineering Laboratory, Institute of Energy and Process Engineering (IEPE), Department of Mechanical and Process Engineering (D-MAVT), ETH Zurich, Sonneggstrasse 3, Zurich, 8092 Switzerland Search for more papers by this authorManon Murdeu Particles Biology Interactions Laboratory, Department of Materials Meet Life, Swiss Federal Laboratories for Materials Science and Technology (Empa), Lerchenfeldstrasse 5, St. Gallen, 9014 Switzerland Search for more papers by this authorPaige J. LeValley Nanoparticle Systems Engineering Laboratory, Institute of Energy and Process Engineering (IEPE), Department of Mechanical and Process Engineering (D-MAVT), ETH Zurich, Sonneggstrasse 3, Zurich, 8092 Switzerland Particles Biology Interactions Laboratory, Department of Materials Meet Life, Swiss Federal Laboratories for Materials Science and Technology (Empa), Lerchenfeldstrasse 5, St. Gallen, 9014 Switzerland Search for more papers by this authorMorris Wolf Macromolecular Engineering Laboratory, Institute of Energy and Process Engineering (IEPE), Department of Mechanical and Process Engineering (D-MAVT), ETH Zurich, Sonneggstrasse 3, Zurich, 8092 Switzerland Search for more papers by this authorCharlotte Meyer Nanoparticle Systems Engineering Laboratory, Institute of Energy and Process Engineering (IEPE), Department of Mechanical and Process Engineering (D-MAVT), ETH Zurich, Sonneggstrasse 3, Zurich, 8092 Switzerland Particles Biology Interactions Laboratory, Department of Materials Meet Life, Swiss Federal Laboratories for Materials Science and Technology (Empa), Lerchenfeldstrasse 5, St. Gallen, 9014 Switzerland Search for more papers by this authorOscar Cipolato Nanoparticle Systems Engineering Laboratory, Institute of Energy and Process Engineering (IEPE), Department of Mechanical and Process Engineering (D-MAVT), ETH Zurich, Sonneggstrasse 3, Zurich, 8092 Switzerland Particles Biology Interactions Laboratory, Department of Materials Meet Life, Swiss Federal Laboratories for Materials Science and Technology (Empa), Lerchenfeldstrasse 5, St. Gallen, 9014 Switzerland Search for more papers by this authorMark W. Tibbitt Macromolecular Engineering Laboratory, Institute of Energy and Process Engineering (IEPE), Department of Mechanical and Process Engineering (D-MAVT), ETH Zurich, Sonneggstrasse 3, Zurich, 8092 Switzerland Search for more papers by this authorJachym Rosendorf Department of Surgery, Faculty of Medicine in Pilsen, Charles University, Alej Svobody 923/80, Pilsen, 32300 Czech Republic Biomedical Center, Faculty of Medicine in Pilsen, Charles University, Alej Svobody 1655/76, Pilsen, 32300 Czech Republic Search for more papers by this authorVaclav Liska Department of Surgery, Faculty of Medicine in Pilsen, Charles University, Alej Svobody 923/80, Pilsen, 32300 Czech Republic Biomedical Center, Faculty of Medicine in Pilsen, Charles University, Alej Svobody 1655/76, Pilsen, 32300 Czech Republic Search for more papers by this authorThomas Rduch Particles Biology Interactions Laboratory, Department of Materials Meet Life, Swiss Federal Laboratories for Materials Science and Technology (Empa), Lerchenfeldstrasse 5, St. Gallen, 9014 Switzerland Department of Gynecology and Obstetrics (Frauenklinik), Cantonal Hospital St. Gallen (KSSG), Rorschacherstrasse 95, St. Gallen, 9007 Switzerland Search for more papers by this authorInge K. Herrmann Nanoparticle Systems Engineering Laboratory, Institute of Energy and Process Engineering (IEPE), Department of Mechanical and Process Engineering (D-MAVT), ETH Zurich, Sonneggstrasse 3, Zurich, 8092 Switzerland Particles Biology Interactions Laboratory, Department of Materials Meet Life, Swiss Federal Laboratories for Materials Science and Technology (Empa), Lerchenfeldstrasse 5, St. Gallen, 9014 Switzerland Ingenuity Laboratory, University Hospital Balgrist, Forchstrasse 340, Zurich, 8008 Switzerland Faculty of Medicine, University of Zurich, Rämistrasse 71, Zurich, 8006 Switzerland Search for more papers by this authorGraphical Abstract Women's Health Reversible hydrogel implants for fallopian tube occlusion offer a potential solution for both reversible contraception and mechanical prevention of endometriosis. The soft hydrogel implant effectively blocks fallopian tubes, prevents sperm and endometrial cell crossing, and can be safely removed on demand by hysteroscopic light application. More details can be found in article number 2310301 by Alexandre H.C. Anthis, Inge K. Herrmann, and co-workers. Article Metrics Total unique accesses to an article’s full text in HTML or PDF/ePDF format.More metric information Scite metrics Explore this article's citation statements on scite.ai Share QR Code Generating QR code QR code copied to clipboard! Something went wrong while generating your QR code. Please try again in a moment. If the issue persists, refresh the page or contact support. Export citation Unable to load citation data. Please try again in a moment. How to cite Elkins, L. J., & Spiegelman, M. (2021). pyUserCalc: A revised Jupyter notebook calculator for uranium-series disequilibria in basalts. 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