[Adjuvant therapy in uterine myoma].

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AI-generated summary by claude@2026-06, 2026-06-09

Adjuvant therapy effectiveness in uterine myoma depends on tumor sensitivity to hormones, dosage, and duration, with indications limited to small myomas concurrent with benign endometrial hyperplasia and/or early endometriosis.

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Abstract

Many-year studies and clinical experience with steroidal and peptide sexual hormone agonists and antagonists of different generations provides a pathogenetic concept for their use in the treatment of patients with uterine myoma. The impact of adjuvant therapy has been found to be determined by tumor tissue sensitivity to hormonal effects, dosages, therapy duration to a greater extent than the type of a drug from this group. The scope of indications for drug use to suppress the growth of a tumor is limited by its small sizes and its concurrence with benign endometrial hyperplastic processes and/or early internal genital endometriosis.

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Condition tags

endometriosis

MeSH descriptors

Leiomyoma Uterine Neoplasms Adult Age Factors Chemotherapy, Adjuvant Clinical Trials as Topic Danazol Danazol Estradiol Estradiol Estrogen Antagonists Estrogen Antagonists Female Follicle Stimulating Hormone Follicle Stimulating Hormone Gestrinone Gestrinone Humans Leiomyoma Leiomyoma

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europepmc
last seen: 2026-08-10T06:11:17.106188+00:00
openalex
last seen: 2026-06-04T00:00:01.174412+00:00
pubmed
last seen: 2026-05-13T22:10:52.568893+00:00
License: CC0 · commercial use OK