Safe total intrafascial laparoscopic (TAIL) hysterectomy: a prospective cohort study.

A total of 3,066 patients fulfilled the inclusion criteria and could be included in this study. 993 of the total number of patients underwent AH, 642 VH and 1,431 TAIL™ hysterectomy. Table  1 shows the characteristics of the patients, including age, body mass index, operation times and duration of hospital stays. Mean age shows a difference between the groups. The women in the TAIL™ hysterectomy group are statistically significantly older when compared to the AH and VH groups. Mean body mass index also differs between the three groups. It is significantly lower in the TAIL™ hysterectomy group compared to the VH and AH groups. There is no statistically significant difference for the operation times comparing the three groups. The mean hospital stay in the TAIL™ hysterectomy, VH and AH groups is 5.8 ± 2.4, 8.8 ± 4.0 and 10.4 ± 3.9 days, respectively. Statistically significant differences are demonstrated. Table 1 Demographic and operative characteristics TAIL™ hysterectomy AH ( n  = 642) VH ( n  = 642) Comparison TAIL™-AH Tail™-VH AH-VH Age (years) 56.4 ± 14.5 50.0 ± 11.1 46.9 ± 8.9 p  < 0.01 p  < 0.01 p  < 0.01 Body mass index 24.9 ± 2.8 26.7 ± 3.5 27.1 ± 2.9 p  < 0.01 p  < 0.01 n.s. Operation time (min)  0–30 12 (0.8%) 5 (0.5%) 16 (2.5%) n.s. n.s. n.s.  31–60 272 (19%) 165 (17%) 167 (26%) n.s. n.s. n.s.  61–120 739 (52%) 481 (48%) 322 (50%) n.s. n.s. n.s.  121–180 333 (22%) 264 (26.5%) 112 (17%) n.s. n.s. n.s.  >180 75 (5.2%) 78 (8%) 25 (3.9%) n.s. n.s. n.s. Hospital stay (days) 5.8 ± 2.4 10.4 ± 3.9 8.8 ± 4.0 p  < 0.025 p  < 0.025 p   0.025 Demographic and operative characteristics Data are reported as mean ± SD or number (%) n.s.: p  > 0.025 Table  2 shows the symptoms and diagnoses for the three groups of patients. Dysfunctional uterine bleeding, cervical intraepithelial neoplasia and genital prolapse are more frequent in the VH group as compared to the TAIL™ hysterectomy group, whereas the frequency of the diagnosis of postmenopausal bleeding, uterus myomatosus, benign adnexal tumours and endometrioses is higher in the TAIL™ hysterectomy group than in the VH group. Table 2 Symptoms and diagnoses TAIL ( n  = 1,431) AH ( n  = 993) VH ( n  = 642) Dysfunctional uterine bleeding 655 (45.7%) 412 (41.5%) 349 (54.4%) Postmenopausal bleeding 109 (7.6%) 69 (7%) 31 (4.8%) Cervical intraepithelial neoplasie 65 (4.5%) 32 (3.2%) 64 (10%) Adenomyosis 221 (15.4%) 141 (14.2%) 82 (12.7%) Uterus myomatosus 758 (52.9%) 506 (51%) 240 (37.4%) Benign adnexal tumours 131 (9.2%) 107 (10.8%) 9 (1.4%) Genital prolapse 156 (10.9%) 145 (14.6%) 120 (18.7%) Incontinence 115 (8%) 60 (6%) 52 (8.1%) Endometriosis 122 (8.5%) 88 (8.9%) 10 (1.5%) Dysmenorrhea 241 (16.8%) 70 (7%) 128 (19.9%) Dyspareunia 62 (4.3%) 47 (4.7%) 30 (4.7%) Abdominal pain 25 (1.7%) 21 (2.1%) 11 (1.7%) Miscellaneous 45 (3.1%) 29 (2.9%) 21 (3.3%) Patients may have multiple symptoms and/or diagnoses Symptoms and diagnoses Patients may have multiple symptoms and/or diagnoses Major complications are shown in Table  3 . Major haemorrhage with consecutive reoperation is observed to be statistically significantly more frequent in the AH group when compared to the TAIL™ hysterectomy group, with an O.R. of 6.13 (CI 3.05–12.62). An analogous observation is described when the AH group is compared to the VH group (O.R. 3.0, CI 1.45–6.39). For thromboembolic complications, a statistically significant difference is found: The AH group shows a statistically significantly higher incidence when compared to the TAIL™ hysterectomy group, with an O.R. of 16.0 (CI 2.06–124). The total rate of reoperations needed is significantly increased in the AH group when compared to the TAIL™ hysterectomy group (O.R. 4.47, CI 2.35–8.63), and also the AH group compared to the VH group shows a statistically significant difference (O.R. 2.42, CI 1.1–5.34). Table 3 Major complications TAIL™ hysterectomy AH VH AH vs TAIL™ VH vs TAIL™ AH vs VH 1432 patients 993 patients 642 patients O.R. ± 95% CI O.R. ± 95% CI O.R. ± 95% CI Major haemorrhage (reoperations) 11 45 10 6.13 (3.05–12.62) n.s. 3.0 (1.45–6.39) Bowel injury 2 4 1 n.s. n.s. n.s. Ureteric injury 1 3 0 n.s. n.s. n.s. Bladder injury 8 8 5 n.s. n.s. n.s. Thromboembolic complications 1 11 1 16.0 (2.06–124) n.s. n.s. Reoperations 3 14 2 4.47 (2.353–8.63) n.s. 2.42 (1.1–5.34) Total of complications 26 (1.8%) 85 (8.6%) 19 (3%) 5.06 (3.17–8.12) n.s. 3.07 (1.8–5.3) At least one major complication 22 (1.5%) 72 (7.3%) 17 (2.7%) 5.01 (3.02–8.38) n.s. 2.87 (1.63–5.11) Values are numbers (percentage) of patients A patient may have more than one complication Major complications Values are numbers (percentage) of patients A patient may have more than one complication Overall, major intra- and postoperative complications occur significantly more frequently in the AH group (8.6%) when compared to the VH group (3%) and the TAIL™ hysterectomy group (1.8%). No statistically significant difference is shown for the comparison of the VH group with the TAIL™ hysterectomy group. The odds ratios and confidence intervals for major complications are 5.06 (CI 3.17–8.12) for AH compared to TAIL™ hysterectomy and 3.07 (CI 1.8–5.3) for AH compared to VH, respectively. Table  4 demonstrates minor complications observed for the three groups, including comparisons of the groups. The postoperative minor complications including infection rates (pelvic infections, fever and significant bacteruria) are low in the TAIL™ hysterectomy group (3.8%) when compared with either the AH group (15.3%) or the VH group (11.2%), respectively. The total of minor complications is statistically significantly lower for TAIL™ hysterectomy as for AH (O.R. 4.52, CI 3.25–6.31) or VH (O.R. 3.16, CI 2.16–4.62). Table 4 Minor complications TAIL™ hysterectomy AH VH AH vs TAIL™ VH vs TAIL™ AH vs VH 1431 patients 993 patients 642 patients O.R. ± 95% CI O.R. ± 95% CI O.R. ± 95% CI Infection 14 42 15 4.47 (2.35–8.63) 2.42 (1.10–5.34) n.s. Ileus 1 3 1 n.s. n.s. n.s. Wound dehiscence 1 2 1 n.s. n.s. n.s. Hematoma, bleeding (not requiring reoperation) 6 7 9 n.s. 3.38 (1.16–9.53) n.s. Significant bacteruria 33 98 46 4.64 (3.05–7.09) 3.27 (2.02–5.59) n.s. Total 55 (3.8%) 152 (15.3%) 72 (11.2%) 4.52 (3.25–6.31) 3.16 (2.16–4.62) 1.43 (1.05–1.95) At least one minor complication 49 (3.4%) 125 (12.6%) 63 (9.8%) 4.06 (2.95–5.8) 3.07 (2.05–4.69) n.s. Total of major and minor complications 81 (5.7%) 237 (23.9%) 91 (14.2%) 5.22 (3.97–6.89) 2.75 (1.98–3.82) 1.90 (1.49–2.5) Values are numbers (percentage) of patients Minor complications Values are numbers (percentage) of patients Overall, the incidence of major and minor complications is lowest in the TAIL™ hysterectomy group compared to either AH or VH, respectively. The odds ratios and CI are 5.22 (3.97–6.89) for AH compared to TAIL™ hysterectomy, 2.75 (1.98–3.82) for VH compared to TAIL™ hysterectomy and 1.90 (1.49–2.50) for AH compared to VH. The incidence of major complications applying the standardised TAIL™ hysterectomy technique is not related to the experience of the surgeons. No differences are found among residents in training and experienced staff surgeons for major complications. These data are summarised in Table  5 . Table 5 Experience of surgeons and incidence of major complications with TAIL™ hysterectomy Major complications Residents in training (620 patients) Staff surgeons (821 patients) Statistic level Major haemorrhage 6 5 n.s. Bowel injury 0 2 n.s. Ureter injury 0 1 n.s. Bladder injury 5 3 n.s. Thromboembolic complications 1 0 n.s. Reoperations 0 3 n.s. Total 12 (1.9 ) 14 (1.7%) n.s. n.s.: p  > 0.05 Experience of surgeons and incidence of major complications with TAIL™ hysterectomy n.s.: p  > 0.05

The presented data are one of the largest prospective observational studies from a single institution. We describe and compare different techniques for total hysterectomy in benign uterus disease. Although there are statistically significant differences in age and body mass index, we feel that these are not in favour of total atraumatic intrafascial laparoscopic (TAIL™) hysterectomy since patients in this group are older. We demonstrate operation times not to vary statistically significantly for the three groups analysed. This observation is not in accordance with earlier published data of other authors [ 1 ]. If the standardised surgical technique for LH, as we describe it in this publication, is applied strictly, the operating procedure is straightforward and operation times are less as described for, e.g. LAVH procedures. Therefore, total laparoscopic hysterectomy does not consume longer operation times than either AH or VH, respectively. As it has been shown in earlier publications, LH is associated with less tissue trauma [ 8 ], less postoperative pain [ 9 ], lower morbidity and less stress response when compared to AH [ 10 ]. This leads to a better acceptance of the procedure and an improvement of quality of life. Symptoms and diagnoses with regard to dysfunctional uterine bleeding, cervical intraepithelial neoplasia, genital prolapse, postmenopausal bleeding, uterus myomatosus, benign adnexal tumours and endometrioses are not equally balanced for the LH and the VH groups. This is in accordance with the published data by David-Montefiore et.al. [ 19 ] and also reflects that in the first years of this study, LH was not yet propagated and accepted as a standard of care for the symptoms and diagnoses mentioned. Optimising health economics by the development of safe and time-saving operation techniques with reduced time of convalescence and hospital treatment days, we present the method of total relatively atraumatic intrafascial laparoscopic (TAIL™) hysterectomy. As a result of this study, we demonstrate that the operation time is equivalent when compared to AH and VH techniques. The mean hospital treatment days are reduced from 9 to 10 days below 6 days. As published evidence shows [ 1 ], reduced postoperative time of convalescence and earlier return to work and social life can be expected. The same is true for the quality of life of patients [ 20 ]. Therefore, shorter hospitalisation time, earlier convalescence, less lost work days and earlier return to social life achieved by the use of this operation technique support health economic aspects. The main outcome results concerning intra- and postoperative complications are at variance with other published reports. The most dreaded complication—the risk of ureteric lesions—has repeatedly been shown to be increased applying the laparoscopic hysterectomy technique as compared to abdominal procedures [ 1 , 2 , 16 , 21 ]. In contrast, we demonstrate that the laparoscopic approach is associated with a very low incidence of these complications discussed. We describe the development and consequent application of a uterine device designed to facilitate the single operation steps increasing especially the safety of the operation technique. The following step-by-step operation protocol as described here is essential to achieve the results presented for fast operation times with low incidences of complications. Every potential “dangerous” step of the operation procedure, e.g. the dissection of the uterine vessels, is performed in direct contact with the surgical platform. The device is designed to remove the bladder and ureter far away from the dissection plane. Our LH method is an intrafascial technique. This is also essential to increase the safety of the operation. Intrafascial detachment of the cervix decreases the risk for ureteral and/or bladder injuries even under difficult conditions, e.g. large uteri or the situation of a frozen pelvis. As described, there is no need for dissection of the bladder from the vagina; this is another advantage using this technique. In our study population, eight bladder lesions (0.6%) occurred in patients with scarring of the lower uterine segment after caesarean section. This is in accordance with published data for AH and VH and does, also in our study population, not show any statistically significant difference when compared to the AH and VH groups. Our results are also supported by the recent published data of a large series of LH demonstrating no association with an increase of major complication rates [ 7 ]. The analysed major complications include bleeding, defined as the need of reoperation and the requirement of blood transfusions. In our population, this complication is documented significantly more frequently for AH than for TAIL™ hysterectomy (OR 6.13 (CI 3.05–12.62). This observation can be explained by the anatomic dissection and the relatively atraumatic technique of the TAIL™ hysterectomy. In contrast to Garry et al. [ 16 ] who found no significant differences for the postoperative minor complications including infection rates. In our study, these are significantly lower in the LH group (3.8%) as either in the AH (15.3%) or VH (11.2%) group. These data demonstrate that our LH technique is applicable and safe if the developed uterine device is applied correctly and used as a surgical platform and if the operation is followed step-by-step consequently as described. The face-to-face sutured endopelvic fascia at the vaginal level might help prevent postoperative ascending infections. Also, this tight approximation of fascial tissue might promote fibroblast proliferation and help in sealing the wound and probably prevents postoperative ascending infections. The short operation times and the avoidance of extensive coagulation seem to be important too. With the technique of intrafascial dissection of the cervix, most parts of the cardinal and sacrouterine ligaments remain attached. The vaginal closure by the use of laparoscopic sutures unifies the ligaments, and during closure, a shortening of the ligaments can be achieved, if the tissue is very lax, by placing extra sutures on the sacrouterine ligaments and vagina. This operation step might contribute to a reduction of the indecency of post-hysterectomy vaginal vault prolapse. This hypothesis, however, needs to be confirmed by a long follow-up. In summary, we observe, in contrast to others, a statistically significantly lower incidence of complications in the TAIL™ hysterectomy group when compared to either vaginal or abdominal procedures. We acknowledge that our results might be biased by the fact that our data represent a prospective observational study and not a randomised trial. However, the clinical importance of our findings is underlined by the large number of patients. In addition, our data are supported by the results of Donnez et al. [ 7 ] demonstrating no increased major complication rate for LH in a similar huge patient population as presented in our study. All our patient data were collected in a single institution, including staff surgeons and residents in training as gynaecologic surgeons. The analysis of the data presented shows no difference in the incidence of complications comparing residents in training as surgeons with experienced gynaecologic surgeons. This again is in contrast to the experience of other authors [ 22 – 24 ]. We postulate that the consequent following of the step-by-step operation procedure is crucial to guarantee a long-term high quality of outcome. The strict application of the standardised technique is a prerequisite for effective teaching and learning of this surgical technique. The presented data will encourage and serve as a strong argument for better acceptance of the total laparoscopic hysterectomy technique among gynaecologists as discussed earlier in the literature [ 5 ]. Therefore, they serve as a fundament and raise the potential of this technique to popularise the minimal invasive approach. Thus, patients with benign uterus disorders may benefit from the proven advantages, e.g. less perioperative blood loss, reduction of postoperative pain, lower incidence of postoperative infections and shorter convalescence, respectively, without undergoing an increased risk for perioperative complications.

All patients admitted between 1997 and 2008 for hysterectomy with or without adnexectomy due to benign uterine disease were included in this prospective, cohort study. Patient data were collected prospectively pre-, intra- and postoperative. Complications were documented using a standardised data sheet of a Swiss obstetric and gynaecological study group (Arbeitsgemeinschaft Schweizerische Frauenkliniken, Amlikon/Switzerland) [ 15 ]. Inclusion and exclusion criteria as well as the outcome were defined. For the analysis, patient identification was removed. The quality of the data recorded was ensured by a two-step control system. First, the completeness and exactness of all data were verified at our centre by a data controller and double checked by a senior gynaecologist. Then, the data were sent to the central registry of the Swiss study group, and there, the accuracy of all data entered in the database was assessed again by the data centre quality control group. In case of discrepancy, data were returned for verification and correction. Information on patient characteristics, surgical procedures, intra- and postoperative complications was documented in the database. The choice of the operative procedure (AH, VH or TAIL™ hysterectomy) was based on patient preferences after a thorough discussion of risks and benefits. Complications were classified as previously reported [ 16 ] with some minor modifications. Major complications were classified as follows: Major haemorrhage: requiring transfusion or reoperation Bowel, ureteric or bladder injury Deep venous thrombosis and pulmonary embolus (diagnosed by ultrasound, angiography, perfusion/ventilation scintigraphy or CT scan) Reoperation for postoperative bleeding or unintended laparotomy Major haemorrhage: requiring transfusion or reoperation Bowel, ureteric or bladder injury Deep venous thrombosis and pulmonary embolus (diagnosed by ultrasound, angiography, perfusion/ventilation scintigraphy or CT scan) Reoperation for postoperative bleeding or unintended laparotomy Minor complications were defined as: Infections (pelvic infection or fever >38°C, two consecutive days) Abdominal or vaginal bleeding or haematoma not requiring reoperation Ileus Wound dehiscence Significant bacteruria Infections (pelvic infection or fever >38°C, two consecutive days) Abdominal or vaginal bleeding or haematoma not requiring reoperation Ileus Wound dehiscence Significant bacteruria The study was approved by the ethical committee of the Institutional Review Board, Kantonsspital Baden, Switzerland. All vaginal and abdominal hysterectomies were performed with a standard surgical technique [ 17 ]. Patients in the LH group were operated by application of a step-by-step standardised operation technique, the so-called total atraumatic intrafascial laparoscopic hysterectomy (TAIL™ hysterectomy). A totally reusable instrument (Hohl Manipulator, Storz AG, Tuttlingen/Germany) with an anatomical design as a uterine device was used in all patients being operated by the LH technique. The instrument consists of a strong handle, manipulator rod, cervical cup platform in three different sizes for small, medium and large cervices, spiral threads in two sizes for a tight and secure endocervical fixation of the instrument and Hegar-type rod extensions for small and large uteri (Fig.  1 and Video 1 ). Tight endocervical fixation of the thread allows moving even a large uterus in all directions and applying strong tension to the tissue. Fig. 1 Uterine manipulator with cup, thread, extension, rod and handle Uterine manipulator with cup, thread, extension, rod and handle The cervical cup withstands electric and sonar energy and delineates exactly the border between the vagina and cervix. It serves as a surgical platform. Crucial surgical steps, e.g. bicoagulation of uterine vessels and intrafascial detachment of ligaments and vagina, are all performed in direct contact with the fringe of the cup (Video 2 ). These cups have a special design to adapt to the anatomy of the anterior and posterior vaginal fornices (Fig.  1 ). The patient is positioned in laparoscopic dorsal lithotomy position. Buttocks have to be positioned on the lower edge of the operation table to allow free manipulation with the instrument in all directions. The patient’s position is maintained by the use of shoulder supports and in recent years by special retraining mattresses on the operation table. Cranial sliding even in deep Trendelenburg position is thus mostly prevented. A tenaculum is placed on the anterior lip of the cervix and the cervix is dilated to Hegar 6. The length of the uterus cavity is measured. The size of the spiral thread is chosen according to the dimensions of the cervical canal (wide or narrow) and Hegar-type rod extensions according to uterine cavity length. Then, spiral threads are very tightly screwed into the endocervix to move even large uteri in all directions and apply strong tension to the tissues. The manipulator handpiece with an attached cup is gently introduced into the vagina with light rotating movements (Fig.  2 ). It has to be ensured that the extended side of the manipulator cup is located dorsally. Only after the manipulator handpiece has been advanced cranially as far as possible it is screwed to the manipulator probe. As a result, the edge of the manipulator cup is exactly located at the boundary of the cervix and the vagina (Video 1 ). Fig. 2 Application of the uterine device Application of the uterine device A 10-mm port is placed in the umbilicus or even cranial to the umbilicus in cases of very large uteri. Three secondary 5-mm (two on the left side and one on the right side) ports are positioned very laterally for the application of surgical instruments. A 30° optical system is used for navigation in cases with large uteri. Using this optical system, better access to the ligaments is achieved. Bipolar or vapor pulse coagulation (VPC-Gyrus PlasmaKinetic®) applied with a grasping forceps with an integrated scalpel or bipolar and monopolar forceps or hooks are used for the dissection of the tissues. Step 1. The uterine device is pushed strongly to the contralateral side to create maximal tension. The left utero ovarian ligament, fallopian tube and the round ligament are grasped stepwise for dissection. Step 2. The anterior leaf of the peritoneum is incised and dissected stepwise in the direction of the cervix. The vesicovaginal peritoneum is opened and dissected. If there was no previous caesarean section, the dissection of the bladder from the cervix is obviated by strong pressure on the uterine instrument to push the uterus into the cranial direction (Fig.  3 ). Step 3. Steps 1 and 2 are performed on the right side in analogy to the left side. Step 4. With large uteri, access to the ligaments and posterior fornix is often blocked. Therefore, we approach the uterine arteries anteriorly. The manipulator cup is rotated to the contralateral side of the uterine artery (e.g. to the right side when the left uterine artery is dissected) which is then grasped whilst the back of the electric instrument touches the fringe of the cup (in safe distance from ureter and bladder, Fig.  4 ). Dissection of the uterine artery can therefore be performed safely even in difficult anatomical situations, e.g. frozen pelvis or advanced endometriosis. In this way, blood circulation to the uterus is completely stopped. Step 5. Thus, large uteri with blocked access to the lateral and posterior ligaments may then be reduced in volume without any further blood loss using an electrical morcellator before cervical detachment. Vaginal manipulation of the uterus in all directions greatly facilitates morcellation (sometimes pulling the uterus towards the vagina). Step 6. The fringe of the cup used serves as a platform to navigate around the cervix. If there are adhesions of the rectum cranial to the vaginal line of incision, they must be lysed first. This is facilitated by stretching tissues by applying strong pressure on the cup of the device. Step 7. Cardinal and sacrouterine ligaments are stretched to a maximum applying strong cranial pressure. The extraserosal pelvic fascia can be dissected at the level of the paracervix [ 18 ], keeping the “fascial ring” completely intact (Fig.  5 ). The vagina is dissected following exactly the fringe of the cup using monopolar blended current applied by scissors or a hook. The pneumoperitoneum is still maintained through maximal pressure on the vaginal walls by the device. After complete detachment of the uterus, it is partially removed from the vagina but left in the vaginal canal to maintain the pneumoperitoneum until laparoscopic suturing is accomplished. Step 8. Usually three to four Z-sutures, using 1–0 polydiaxonon (PDS, Ethicon), incorporating cardinal and sacrouterine ligaments as well as posterior and anterior endopelvic fascia are needed to close the vagina. The sutures are knotted extracorporally (Fig.  6 ). A “face-to-face” closure of the fascial plane is strived for. With our technique, we remove the uterus intrafascially, but during closure, a shortening of the ligaments can be achieved if the tissue is very lax by placing extra sutures on the sacrouterine ligaments and vagina. Bipolar coagulation should be avoided whenever possible. The peritoneum remains open. Hemostasis is checked and a copious lavage using warm ringer lactate is done. Fig. 3 Strong cranial pressure to the uterine device obviates the need for bladder dissection Fig. 4 Anterior approach to the uterine arteries. The back of the bicoagulation instrument touches the fringe of the cup Fig. 5 Intrafascial detachment of the uterus from ligaments and the vagina Fig. 6 Closure of the vagina and reconstruction of the fascia by face-to-face closure The uterine device is pushed strongly to the contralateral side to create maximal tension. The left utero ovarian ligament, fallopian tube and the round ligament are grasped stepwise for dissection. The anterior leaf of the peritoneum is incised and dissected stepwise in the direction of the cervix. The vesicovaginal peritoneum is opened and dissected. If there was no previous caesarean section, the dissection of the bladder from the cervix is obviated by strong pressure on the uterine instrument to push the uterus into the cranial direction (Fig.  3 ). Steps 1 and 2 are performed on the right side in analogy to the left side. With large uteri, access to the ligaments and posterior fornix is often blocked. Therefore, we approach the uterine arteries anteriorly. The manipulator cup is rotated to the contralateral side of the uterine artery (e.g. to the right side when the left uterine artery is dissected) which is then grasped whilst the back of the electric instrument touches the fringe of the cup (in safe distance from ureter and bladder, Fig.  4 ). Dissection of the uterine artery can therefore be performed safely even in difficult anatomical situations, e.g. frozen pelvis or advanced endometriosis. In this way, blood circulation to the uterus is completely stopped. Thus, large uteri with blocked access to the lateral and posterior ligaments may then be reduced in volume without any further blood loss using an electrical morcellator before cervical detachment. Vaginal manipulation of the uterus in all directions greatly facilitates morcellation (sometimes pulling the uterus towards the vagina). The fringe of the cup used serves as a platform to navigate around the cervix. If there are adhesions of the rectum cranial to the vaginal line of incision, they must be lysed first. This is facilitated by stretching tissues by applying strong pressure on the cup of the device. Cardinal and sacrouterine ligaments are stretched to a maximum applying strong cranial pressure. The extraserosal pelvic fascia can be dissected at the level of the paracervix [ 18 ], keeping the “fascial ring” completely intact (Fig.  5 ). The vagina is dissected following exactly the fringe of the cup using monopolar blended current applied by scissors or a hook. The pneumoperitoneum is still maintained through maximal pressure on the vaginal walls by the device. After complete detachment of the uterus, it is partially removed from the vagina but left in the vaginal canal to maintain the pneumoperitoneum until laparoscopic suturing is accomplished. Usually three to four Z-sutures, using 1–0 polydiaxonon (PDS, Ethicon), incorporating cardinal and sacrouterine ligaments as well as posterior and anterior endopelvic fascia are needed to close the vagina. The sutures are knotted extracorporally (Fig.  6 ). A “face-to-face” closure of the fascial plane is strived for. With our technique, we remove the uterus intrafascially, but during closure, a shortening of the ligaments can be achieved if the tissue is very lax by placing extra sutures on the sacrouterine ligaments and vagina. Bipolar coagulation should be avoided whenever possible. The peritoneum remains open. Hemostasis is checked and a copious lavage using warm ringer lactate is done. Strong cranial pressure to the uterine device obviates the need for bladder dissection Anterior approach to the uterine arteries. The back of the bicoagulation instrument touches the fringe of the cup Intrafascial detachment of the uterus from ligaments and the vagina Closure of the vagina and reconstruction of the fascia by face-to-face closure The stepwise operation procedure is documented by Video 1 and Video 2 added to this publication. Data were evaluated for normal distribution by Kolmogorov–Smirnov test, and non-parametric tests were applied if required. Statistical significance level was placed at 0.025 by the Bonferroni correction for comparison of groups. Statistical evaluations were obtained by SPSS 10.0.7 Chicago Illinois, Medcalc 9.3.0.0 Belgium or Statcalc 5.0.

Below is the link to the electronic supplementary material. ESM 1 (MPG 6872 kb) ESM 2 (WMV 103313 kb) (MPG 6872 kb) (WMV 103313 kb)