The clinical significance of natural autoimmunity in patients with adhesive process and external genital endometriosis

N. R. Karakashian, E. I. Manukhina, M. A. Gevorgyan, И. Б. Манухин
In: Medical Council · 2016 · pp. 100–101 · doi:10.21518/2079-701x-2016-2-100-101 · W2613580580
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⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

This study evaluated natural autoimmunity in 71 patients with adhesive process and external genital endometriosis, finding that correcting immunological disorders improves reproductive function recovery after surgery and antigonadotropic therapy.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-08 ⓘ

The paper discusses the clinical significance of “natural autoimmunity” in patients who have an adhesive process and external genital endometriosis, aiming to relate baseline autoimmune reactivity to these conditions. At a high level, it presents a clinical analysis focused on how natural autoimmunity may be manifested in this patient group. The main caveat is that the provided text includes only bibliographic details and the abstract/title metadata, without methodological specifics, results, or explicitly stated limitations. Relevance to endometriosis: the study’s core focus is explicitly on patients with external genital endometriosis together with adhesive pelvic processes.

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Abstract

The article presents the results of a study of 71 patients with adhesive process diagnosed with external genital endometriosis (EGE) confirmed by laparoscopy. In accordance with the specific serum immunoreactivity evaluation, all patients were divided into 3 groups: Group A (normal response type), Group B (hyper-response type) and group C (hypo-response type). The duration of infertility was on average 6,1 ± 1,3 years. After surgery patients underwent antigonadotropic therapy with 3.75 mg buserelin (a course of 4--6 injections). Against a background of the baseline therapy, all patients in groups B and C underwent correction of immunological disorders. Conclusion: Management of immunological disorders in patients with adhesive process associated with EGE enhances the effectiveness of recovery of the reproductive function

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endometriosisinfertility

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last seen: 2026-06-10T17:14:06.276822+00:00
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