"STUDY OF ENDOMETRIOSIS RELATED INFERTILITY, A COMPARATIVE STUDY"

N. Khadem Sh. Jalali Mazlouman
In: Acta Medica Iranica, Vol 42, Iss 5, Pp 383-389 (2004) · 2004 · W4302341056
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This case-control study found a significantly higher prevalence of endometriosis in infertile women (38%) compared to fertile women (11.6%), establishing a meaningful relation between the two conditions.

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This case-control study compared endometriosis frequency and severity between 100 infertile women and 120 fertile multiparous control women, using descriptive statistics with Student t tests and chi-square tests. Endometriosis was diagnosed in 38% of infertile women versus 11.6% of fertile controls (P=0.002), with the highest prevalence around age 26, and the mean duration of infertility was similar whether or not endometriosis was present. The authors report that diagnostic time interval was not related to infertility or the severity of endometriosis, and that age-related factors did not affect fertility among women with endometriosis; they also note a major caveat that prevalence in this Iranian study population was higher than reported elsewhere. This paper is centrally about endometriosis — it examines endometriosis-related infertility through a comparative case-control design.

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Abstract

It seems that endometriosis plays an important role in female factor infertility but a clear causal relationship has yet to be established. This case-control study was conducted to determine and compare the frequency and severity of endometriosis in 100 infertile women and 120 fertile multi-para women as control group. Descriptive statistics, Student t test and Chi square test were used in analyzing data. Endometriosis was diagnosed in 38% of infertile versus 11.6% in fertile women (P=0.002). The mean age of women with endometriosis was 27.9±6.1 years; maximum prevalence of endometriosis was observed at 26 years of age. The mean duration of infertility was 4.3±1.9 years in women with endometriosis and 4.6±1.2 years in women without endometriosis. The prevalence of endometriosis in study population was comparatively higher than what has been reported in studies from other countries. There was a significant relation between endometriosis and infertility. Diagnostic time interval had no relation with infertility and severity of endometriosis. Age-related factors did not have any effect on fertility in women with endometriosis. Our study demonstrates a meaningful relation between endometriosis and infertility. Endometriosis may have a higher prevalence in Iranian population.
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Acta Medica Iranica (Oct 2004) "STUDY OF ENDOMETRIOSIS RELATED INFERTILITY, A COMPARATIVE STUDY" Abstract It seems that endometriosis plays an important role in female factor infertility but a clear causal relationship has yet to be established. This case-control study was conducted to determine and compare the frequency and severity of endometriosis in 100 infertile women and 120 fertile multi-para women as control group. Descriptive statistics, Student t test and Chi square test were used in analyzing data. Endometriosis was diagnosed in 38% of infertile versus 11.6% in fertile women (P=0.002). The mean age of women with endometriosis was 27.9±6.1 years; maximum prevalence of endometriosis was observed at 26 years of age. The mean duration of infertility was 4.3±1.9 years in women with endometriosis and 4.6±1.2 years in women without endometriosis. The prevalence of endometriosis in study population was comparatively higher than what has been reported in studies from other countries. There was a significant relation between endometriosis and infertility. Diagnostic time interval had no relation with infertility and severity of endometriosis. Age-related factors did not have any effect on fertility in women with endometriosis. Our study demonstrates a meaningful relation between endometriosis and infertility. Endometriosis may have a higher prevalence in Iranian population.

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endometriosisinfertility

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