Vitamin Antioksidan Sebagai Terapi Potensial Untuk Mengurangi Nyeri Pada Endometriosis

Vitamin Antioksidan Sebagai Terapi Potensial Untuk Mengurangi Nyeri Pada Endometriosis Sari Endometriosis termasuk penyakit ginekologi yang bersifat kronis yang rentan dialami oleh wanita usia reproduktif. Neuroinflamasi pada endometriosis berkaitan dengan adanya nyeri pelvis kronis. Salah satu permasalahan infertilitas pada wanita biasanya disebabkan oleh endometriosis. Penurunan kadar antioksidan ditemukan secara umum pada penderita endometriosis. Vitamin merupakan senyawa yang mengandung tinggi antioksidan dan memiliki potensi suportif dalam inhibisi produksi ROS dan stress oksidatif. Tujuan dari penelitian adalah mengkaji efektivitas vitamin antioksidan dalam meredakan nyeri pada endometriosis. Penelitian ini adalah Narrative Literature Review yang diambil dari database PubMed, Google Scholar dan ProQuest dengan kata kunci kata kunci vitamin, antioxidant, vitamin B, vitamin C, vitamin D, vitamin E, endometriosis, endometrioma, pelvic pain. Artikel dipilih memenuhi kriteria inklusi dan eksklusi yang telah ditentukan. Pada review ini didapatkan bahwa suplementasi vitamin B2, B6, B12, vitamin C, vitamin D dan vitamin E yang diberikan pada wanita yang menderita endometriosis dapat mengurangi gejala nyeri endometriosis secara signifikan. Oleh karena itu, konsumsi mikronutrien seperti vitamin antioksidan sangat direkomendasikan sebagai terapi alternatif dalam mengobati endometriosis karena memiliki efek antiinflamasi, antiangiogenik, anti proliferasi, dan imunomodulator. Kata Kunci Teks Lengkap: PDFReferensi Abramiuk, M., Mertowska, P., Frankowska, K., & Swiechowska-starek, P. (2024). How can selected dietary ingredients influence the development and progression of endometriosis? Nutrients, 16(1), 154. Al-naggar, M. A., Saeed, I., Abdelfattah, A. T., & Al-naggar, M. A. (2022). Role of antioxidants (vitamin E and vitamin C) supplementation for management of chronic pelvic pain related to endometriosis. 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