Protein anabolism in endometrium and myometrium during the growth of induced deciduoma in rats

In: Experientia · 1980 · vol. 36(10) , pp. 1154–1156 · doi:10.1007/bf01976095 · PMID:7418789 · W1964030380
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Abstract

Protein anabolism in the endometrium and myometrium was studied during the growth of induced deciduoma in terms of incorporation of [14C]-leucine into proteins. The data show that the specific activity of the proteins was highest 2 days after decidualisation. Protein synthesis in the endometrium studied on that day as a function of time after injection of the labelled amino acid showed a steady increase during the first 2 h. Cycloheximide (2 mg/kg b.wt) administration produced nearly 95% inhibition of protein synthesis in endometrium as well as in myometrium.

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