BiRDeE – Birth Register for Deep Endometriosis: Collection of delivery data from women with deep endometriosis (with and without prior surgery)

The BiRDeE study (Birth Register for Deep Endometriosis) investigated delivery and peripartum parameters in women with diagnosed deep endometriosis (DE), including obstetric injuries, delivery mode, and neonatal outcomes, using an international, noninterventional multicenter patient register of singleton live births after DE diagnosis (both operated and non-operated). Participating obstetric facilities entered data via a secure web-based system after ethics approval and registration in DRKS (DRKS00016768). From 257 analyzed cases (after drop-out criteria), delivery modes were reported as spontaneous vaginal (38.5%), instrumental vaginal (12.9%), planned primary cesarean (28.0%), and unplanned secondary cesarean (20.6%), with a median gestational age of 40 weeks and a preterm delivery rate of 10.1%. The paper notes that DE per se is not presented as a contraindication to vaginal delivery, while emphasizing the observed high cesarean rate and referring to an already published interim analysis. This paper is centrally about endometriosis — it establishes and reports initial findings from an international birth register focused on deep endometriosis and delivery outcomes.

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