Adhesions and endometriosis: challenges in subfertility management : (An expert opinion of the ANGEL-The ANti-Adhesions in Gynaecology Expert PaneL-group).

De Wilde, R L, Alvarez, J, Brölmann, H, Campo, R., Cheong, Y., Lundorff, P, Pawelczyk, L, Roman, H, di Spiezio Sardo, A, Wallwiener, M
2016 · W7075642071
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This expert opinion discusses the challenges of managing subfertility associated with endometriosis, highlighting molecular evidence that the condition negatively impacts ovarian function and pregnancy outcomes through anatomical distortion, inflammation, or oxidative damage.

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This expert opinion discusses the molecular and anatomical mechanisms by which endometriosis negatively impacts ovarian function and subfertility. The authors note that while the exact pathophysiology remains unclear, the condition affects the tubo-ovarian unit through direct distortion, inflammation, oxidative damage to oocytes, and reduced pregnancy outcomes after in vitro fertilization. This paper is centrally about endometriosis — specifically its role in causing subfertility and the associated challenges in managing reproductive outcomes.

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Abstract

There is molecular evidence that endometriosis has a negative impact on the ovaries, although the exact pathophysiology concerning endometriosis-associated subfertility is not known. The negative impact on the tubo-ovarian unit can be directly by distorting the anatomy, indirectly by invoking inflammation or by oxidative damage with poorer-quality oocytes. Endometriosis even seems to have a negative effect on pregnancy outcome after in vitro fertilization.
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Adhesions and endometriosis: challenges in subfertility management : (An expert opinion of the ANGEL-The ANti-Adhesions in Gynaecology Expert PaneL-group). Loading... Identifiers To cite this item, use the following identifier: https://hdl.handle.net/20.500.12530/27464 E-ISSN: 1432-0711 PMID: 26894304 Publication date Advisors Journal Title Journal ISSN Volume Title Metrics Abstract There is molecular evidence that endometriosis has a negative impact on the ovaries, although the exact pathophysiology concerning endometriosis-associated subfertility is not known. The negative impact on the tubo-ovarian unit can be directly by distorting the anatomy, indirectly by invoking inflammation or by oxidative damage with poorer-quality oocytes. Endometriosis even seems to have a negative effect on pregnancy outcome after in vitro fertilization. Description DeCS Terms CIE Terms Bibliographic citation Arch. Gynecol. Obstet..2016 08;(294)2:299-301 Publisher Affiliation Access rights open access

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