War Effect on the trend of Fasting Blood Sugar Levels on Diabetic Mellitus Patients, in Tigray, Ethiopia

War Effect on the trend of Fasting Blood Sugar Levels on Diabetic Mellitus Patients, in Tigray, Ethiopia | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Article War Effect on the trend of Fasting Blood Sugar Levels on Diabetic Mellitus Patients, in Tigray, Ethiopia Mehari Gebre Teklezgi, Gebru Gebremeskel Gebrerufael, Yared Tbebu Gebru, and 1 more This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-4125049/v1 This work is licensed under a CC BY 4.0 License Status: Posted Version 1 posted You are reading this latest preprint version Abstract Background: Diabetes mellitus remains one of the foremost concerns in life insurance, and it is responsible for premature death. Diabetes mellitus is a condition in which the amount of fasting sugar in the blood is too high because the body cannot use it properly. The study was expected to investigate the war effect on the trend of Fasting Blood Sugar Levels of diabetic mellitus patients. Methods: Longitudinal design with different hierarchical models, which are Linear mixed effects, generalized linear mixed effects, and nonlinear mixed effect models were fitted on the data Fasting Blood Sugar Level as a response variable. Results: Results depicted that the Fasting Blood Sugar Level of the patients increased over time. Besides, age, weight, medication, total cholesterol, high-density lipoprotein, creatinine, and linear time effect have positive significant effects whereas triglyceride and low-density lipoprotein have negative significant effects on the FBS level of adult Diabetes mellitus patients. Conclusion: The war has a significant effect on the poor control of blood glucose levels of adult diabetic patients. Due to the war, siege, or blockages, there were rare medicines, the patients were not taking their medicines on time, and they did not get enough insulin as well. Health sciences/Diseases Health sciences/Medical research Health sciences/Medical research/Epidemiology Health sciences/Medical research/Experimental models of disease Diabetic Mellitus Fasting Blood Sugar War effect Linear Mixed Model Full Text Additional Declarations No competing interests reported. Cite Share Download PDF Status: Posted Version 1 posted You are reading this latest preprint version Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. As a division of Research Square Company, we’re committed to making research communication faster, fairer, and more useful. We do this by developing innovative software and high quality services for the global research community. Our growing team is made up of researchers and industry professionals working together to solve the most critical problems facing scientific publishing. Also discoverable on Platform About Our Team In Review Editorial Policies Advisory Board Help Center Resources Author Services Accessibility API Access RSS feed Manage Cookie Preferences © Research Square 2026 | ISSN 2693-5015 (online) Privacy Policy Terms of Service Do Not Sell My Personal Information {"props":{"pageProps":{"initialData":{"identity":"rs-4125049","acceptedTermsAndConditions":true,"allowDirectSubmit":true,"archivedVersions":[],"articleType":"Article","associatedPublications":[],"authors":[{"id":289727872,"identity":"0a4c0fa9-04ac-4c88-b97a-1d048807d410","order_by":0,"name":"Mehari Gebre Teklezgi","email":"data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAZAAAAAyAQMAAABI0h/eAAAABlBMVEX///8AAABVwtN+AAAACXBIWXMAAA7EAAAOxAGVKw4bAAAA4ElEQVRIiWNgGAWjYFACHiA2ADGYDwAJCRmitUgwsLElgLTwEKmFAaSFxwDBxQd023sPfq4oqKvjn9/z+dWNGgseBvbDRzfg02J25lyy5BmDwxISx3i3WeccAzqMJy3tBl4tN3IMJBsMDkgwALUY57ABtUjwmOHXcv+N8c8GgzoJ+WM8z4xz/hGj5QaPGdAWZgmDYzzMj3PbiNFyJsfMssHgsOTGY2lmzLl9EjxsBP1y/IzxzYY/dfxyhw8//pzzrU6On/3wMbxakAGbBJgkVjkIMH8gRfUoGAWjYBSMHAAAGg9D/29DvG4AAAAASUVORK5CYII=","orcid":"","institution":"Adigrat University","correspondingAuthor":true,"prefix":"","firstName":"Mehari","middleName":"Gebre","lastName":"Teklezgi","suffix":""},{"id":289727874,"identity":"1bae6688-794c-4a78-9977-763a2d1c736d","order_by":1,"name":"Gebru Gebremeskel Gebrerufael","email":"","orcid":"","institution":"Adigrat University","correspondingAuthor":false,"prefix":"","firstName":"Gebru","middleName":"Gebremeskel","lastName":"Gebrerufael","suffix":""},{"id":289727876,"identity":"0211a775-80d3-4886-99a4-c90ca75a9db1","order_by":2,"name":"Yared Tbebu Gebru","email":"","orcid":"","institution":"Adigrat University","correspondingAuthor":false,"prefix":"","firstName":"Yared","middleName":"Tbebu","lastName":"Gebru","suffix":""},{"id":289727877,"identity":"657afc75-c543-40c3-a235-d42a60d193ac","order_by":3,"name":"Mengstu Berhe Tekle","email":"","orcid":"","institution":"Mekelle University","correspondingAuthor":false,"prefix":"","firstName":"Mengstu","middleName":"Berhe","lastName":"Tekle","suffix":""}],"badges":[],"createdAt":"2024-03-18 17:29:22","currentVersionCode":1,"declarations":"","doi":"10.21203/rs.3.rs-4125049/v1","doiUrl":"https://doi.org/10.21203/rs.3.rs-4125049/v1","draftVersion":[],"editorialEvents":[],"editorialNote":"","failedWorkflow":false,"files":[{"id":55715167,"identity":"9c57d2bb-2688-44b9-bee5-4be34788a2b8","added_by":"auto","created_at":"2024-05-02 07:24:10","extension":"pdf","order_by":1,"title":"","display":"","copyAsset":false,"role":"manuscript-pdf","size":384879,"visible":true,"origin":"","legend":"","description":"","filename":"Manuscript.pdf","url":"https://assets-eu.researchsquare.com/files/rs-4125049/v1_covered_75b6e6e6-ed61-4ccb-8184-6d83e7bc783f.pdf"}],"financialInterests":"No competing interests reported.","formattedTitle":"War Effect on the trend of Fasting Blood Sugar Levels on Diabetic Mellitus Patients, in Tigray, Ethiopia","fulltext":[],"fulltextSource":"","fullText":"","funders":[],"hasAdminPriorityOnWorkflow":false,"hasManuscriptDocX":false,"hasOptedInToPreprint":true,"hasPassedJournalQc":"","hasAnyPriority":false,"hideJournal":true,"highlight":"","institution":"","isAcceptedByJournal":false,"isAuthorSuppliedPdf":true,"isDeskRejected":"","isHiddenFromSearch":false,"isInQc":false,"isInWorkflow":false,"isPdf":true,"isPdfUpToDate":true,"isWithdrawnOrRetracted":false,"journal":{"display":true,"email":"[email protected]","identity":"researchsquare","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":true,"externalIdentity":"","sideBox":"","snPcode":"","submissionUrl":"/submission","title":"Research Square","twitterHandle":"researchsquare","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"","reportingPortfolio":"","inReviewEnabled":false,"inReviewRevisionsEnabled":true},"keywords":"Diabetic Mellitus Fasting Blood Sugar, War effect, Linear Mixed Model","lastPublishedDoi":"10.21203/rs.3.rs-4125049/v1","lastPublishedDoiUrl":"https://doi.org/10.21203/rs.3.rs-4125049/v1","license":{"name":"CC BY 4.0","url":"https://creativecommons.org/licenses/by/4.0/"},"manuscriptAbstract":"\u003cp\u003e\u003cstrong\u003eBackground: \u003c/strong\u003eDiabetes mellitus remains one of the foremost concerns in life insurance, and it is responsible for premature death. Diabetes mellitus is a condition in which the amount of fasting sugar in the blood is too high because the body cannot use it properly. The study was expected to investigate the war effect on the trend of Fasting Blood Sugar Levels of diabetic mellitus patients.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eMethods: \u003c/strong\u003eLongitudinal design with different hierarchical models, which are Linear mixed effects, generalized linear mixed effects, and nonlinear mixed effect models were fitted on the data Fasting Blood Sugar Level as a response variable.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eResults:\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eResults depicted that the Fasting Blood Sugar Level of the patients increased over time. Besides, age, weight, medication, total cholesterol, high-density lipoprotein, creatinine, and linear time effect have positive significant effects whereas triglyceride and low-density lipoprotein have negative significant effects on the FBS level of adult Diabetes mellitus patients.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eConclusion:\u003c/strong\u003e The war has a significant effect on the poor control of blood glucose levels of adult diabetic patients. Due to the war, siege, or blockages, there were rare medicines, the patients were not taking their medicines on time, and they did not get enough insulin as well.\u003c/p\u003e","manuscriptTitle":"War Effect on the trend of Fasting Blood Sugar Levels on Diabetic Mellitus Patients, in Tigray, Ethiopia","msid":"","msnumber":"","nonDraftVersions":[{"code":1,"date":"2024-04-12 14:34:19","doi":"10.21203/rs.3.rs-4125049/v1","editorialEvents":[{"type":"communityComments","content":0}],"status":"published","journal":{"display":true,"email":"[email protected]","identity":"researchsquare","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":true,"externalIdentity":"","sideBox":"","snPcode":"","submissionUrl":"/submission","title":"Research Square","twitterHandle":"researchsquare","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"","reportingPortfolio":"","inReviewEnabled":false,"inReviewRevisionsEnabled":true}}],"origin":"","ownerIdentity":"55880e86-0cfc-4166-8043-8e3e0a41aa2b","owner":[],"postedDate":"April 12th, 2024","published":true,"recentEditorialEvents":[],"rejectedJournal":[],"revision":"","amendment":"","status":"posted","subjectAreas":[{"id":30509836,"name":"Health sciences/Diseases"},{"id":30509837,"name":"Health sciences/Medical research"},{"id":30509838,"name":"Health sciences/Medical research/Epidemiology"},{"id":30509839,"name":"Health sciences/Medical research/Experimental models of disease"}],"tags":[],"updatedAt":"2024-05-02T07:23:14+00:00","versionOfRecord":[],"versionCreatedAt":"2024-04-12 14:34:19","video":"","vorDoi":"","vorDoiUrl":"","workflowStages":[]},"version":"v1","identity":"rs-4125049","journalConfig":"researchsquare"},"__N_SSP":true},"page":"/article/[identity]/[[...version]]","query":{"redirect":"/article/rs-4125049","identity":"rs-4125049","version":["v1"]},"buildId":"8U1c8b4HqxoKbykW_rLl7","isFallback":false,"isExperimentalCompile":false,"dynamicIds":[84888],"gssp":true,"scriptLoader":[]}