Estrogen (Er- Α) AND Progesterone (Pr- Α) Receptors Expression in Egg Endometriosis

This paper examines the degree of expression of estrogen (ER-α) and progesterone (PR-α) receptors in both glandular epithelium and stromal structures in ovarian endometriosis. As a material, ovarian tissue from 28 patients was immunohistochemically examined. Immunohistochemical examination of ovarian endometriosis revealed differences in the expression of estrogen (ER-α) and progesterone (PR-α) receptors in both epithelial cells and stromal structures. The sensitivity of these tissue structures to hormones during endometriosis, and the formation of specific protein receptors indicates the high rate of expression of the ER-α receptor relative to the PR-α receptor in epithelial cells that have become endometriotic glands relative to stroma structures indicates that the role of the hormone estrogen in the mechanism of endometriosis development is highly important.