Enhanced Second Harmonic Generation through DNA-Integrated Plasmonic Nanoparticles - A Novel Nonlinear Optical Approach

Enhanced Second Harmonic Generation through DNA-Integrated Plasmonic Nanoparticles - A Novel Nonlinear Optical Approach | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Research Article Enhanced Second Harmonic Generation through DNA-Integrated Plasmonic Nanoparticles - A Novel Nonlinear Optical Approach Atro tootoonchi, Javad Karamdel, Ebadollah Naderi, Hassan Ghalami Bavil Olyaee This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-5336086/v1 This work is licensed under a CC BY 4.0 License Status: Posted Version 1 posted You are reading this latest preprint version Abstract This study presents the development of advanced plasmonic nanoparticles specifically designed to amplify Second Harmonic Generation (SHG) signals. The core of this innovative approach lies in the strategic integration of gold and silver nanoparticles with DNA, a synergy meticulously tailored to exploit DNA's exceptional nonlinear optical properties alongside the plasmonic resonances of gold and silver. Unlike traditional plasmonic materials, such as graphene, silicon, and metals themselves, our design leverages DNA not just as a structural element but as a dynamic enhancer of SHG due to its unparalleled photon absorption and interaction capabilities at the nanoscale. Through advanced DNA-based modeling and simulation, we introduce a novel nanoparticle architecture optimized to surpass current SHG efficiency benchmarks, without incorporating gas sensing functionalities. This breakthrough not only signifies a significant leap in the field of nonlinear optics but also opens new avenues for the application of biomolecular components in enhancing plasmonic phenomena. plasmonic nanoparticle DNA second harmonic generation SHG nonlinear optics Full Text Additional Declarations No competing interests reported. Cite Share Download PDF Status: Posted Version 1 posted You are reading this latest preprint version Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. As a division of Research Square Company, we’re committed to making research communication faster, fairer, and more useful. We do this by developing innovative software and high quality services for the global research community. Our growing team is made up of researchers and industry professionals working together to solve the most critical problems facing scientific publishing. Also discoverable on Platform About Our Team In Review Editorial Policies Advisory Board Help Center Resources Author Services Accessibility API Access RSS feed Manage Cookie Preferences © Research Square 2026 | ISSN 2693-5015 (online) Privacy Policy Terms of Service Do Not Sell My Personal Information {"props":{"pageProps":{"initialData":{"identity":"rs-5336086","acceptedTermsAndConditions":true,"allowDirectSubmit":true,"archivedVersions":[],"articleType":"Research Article","associatedPublications":[],"authors":[{"id":373629787,"identity":"a7112ecb-54b6-4669-a021-cf575a70f8f6","order_by":0,"name":"Atro tootoonchi","email":"data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAZAAAAAyAQMAAABI0h/eAAAABlBMVEX///8AAABVwtN+AAAACXBIWXMAAA7EAAAOxAGVKw4bAAAA3klEQVRIiWNgGAWjYDADA2Yg8QGI2dgJqgUqPQDRwtg4A6SFmWgtDAyMzTxQAbyAv4H/4OMPFXfkzdkZ2B/b/Nomzwe07sPHHNxaJA4wMxscOPPMcGcz0JbcvtuGbcwMzJIzt+Gx5gAzm8TBtsMJBodBWnpuMwK1sDHz4tEij6LFsue2PUEtBihaGH7cTiSoxfAws7HBmTOHDTccZmyc2dtwO7mNmbEZr1/kjjc+fFBRcVje4PzhAx9+/LltO7+9+eCHj/i8j4gFxgYGxjYogwTwhxTFo2AUjIJRMFIAAIPxTyNZCi0+AAAAAElFTkSuQmCC","orcid":"","institution":"Islamic Azad University South Tehran Branch","correspondingAuthor":true,"prefix":"","firstName":"Atro","middleName":"","lastName":"tootoonchi","suffix":""},{"id":373629788,"identity":"15072334-fa5e-435f-9a11-789acedb221e","order_by":1,"name":"Javad Karamdel","email":"","orcid":"","institution":"Islamic Azad University South Tehran Branch","correspondingAuthor":false,"prefix":"","firstName":"Javad","middleName":"","lastName":"Karamdel","suffix":""},{"id":373629789,"identity":"cac2c034-d0b7-4c6b-88d0-0fbf391bfe40","order_by":2,"name":"Ebadollah Naderi","email":"","orcid":"","institution":"Islamic Azad University South Tehran Branch","correspondingAuthor":false,"prefix":"","firstName":"Ebadollah","middleName":"","lastName":"Naderi","suffix":""},{"id":373629790,"identity":"bba00a19-d263-4069-acc8-012f61c6f8d9","order_by":3,"name":"Hassan Ghalami Bavil Olyaee","email":"","orcid":"","institution":"Islamic Azad University South Tehran Branch","correspondingAuthor":false,"prefix":"","firstName":"Hassan","middleName":"Ghalami Bavil","lastName":"Olyaee","suffix":""}],"badges":[],"createdAt":"2024-10-26 07:23:08","currentVersionCode":1,"declarations":"","doi":"10.21203/rs.3.rs-5336086/v1","doiUrl":"https://doi.org/10.21203/rs.3.rs-5336086/v1","draftVersion":[],"editorialEvents":[],"editorialNote":"","failedWorkflow":false,"files":[{"id":68337340,"identity":"f61a57d3-d79d-421e-9a29-f33eaf40d093","added_by":"auto","created_at":"2024-11-06 08:22:42","extension":"pdf","order_by":1,"title":"","display":"","copyAsset":false,"role":"manuscript-pdf","size":569359,"visible":true,"origin":"","legend":"","description":"","filename":"manuscript2.pdf","url":"https://assets-eu.researchsquare.com/files/rs-5336086/v1_covered_8de25555-4639-4bf5-8da6-98b848cf8840.pdf"}],"financialInterests":"No competing interests reported.","formattedTitle":"Enhanced Second Harmonic Generation through DNA-Integrated Plasmonic Nanoparticles - A Novel Nonlinear Optical Approach","fulltext":[],"fulltextSource":"","fullText":"","funders":[],"hasAdminPriorityOnWorkflow":false,"hasManuscriptDocX":false,"hasOptedInToPreprint":true,"hasPassedJournalQc":"","hasAnyPriority":true,"hideJournal":true,"highlight":"","institution":"","isAcceptedByJournal":false,"isAuthorSuppliedPdf":true,"isDeskRejected":"","isHiddenFromSearch":false,"isInQc":false,"isInWorkflow":false,"isPdf":true,"isPdfUpToDate":true,"isWithdrawnOrRetracted":false,"journal":{"display":true,"email":"[email protected]","identity":"researchsquare","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":true,"externalIdentity":"","sideBox":"","snPcode":"","submissionUrl":"/submission","title":"Research Square","twitterHandle":"researchsquare","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"","reportingPortfolio":"","inReviewEnabled":false,"inReviewRevisionsEnabled":true},"keywords":"plasmonic, nanoparticle, DNA, second harmonic generation, SHG, nonlinear optics","lastPublishedDoi":"10.21203/rs.3.rs-5336086/v1","lastPublishedDoiUrl":"https://doi.org/10.21203/rs.3.rs-5336086/v1","license":{"name":"CC BY 4.0","url":"https://creativecommons.org/licenses/by/4.0/"},"manuscriptAbstract":"\u003cp\u003eThis study presents the development of advanced plasmonic nanoparticles specifically designed to amplify Second Harmonic Generation (SHG) signals. The core of this innovative approach lies in the strategic integration of gold and silver nanoparticles with DNA, a synergy meticulously tailored to exploit DNA's exceptional nonlinear optical properties alongside the plasmonic resonances of gold and silver. Unlike traditional plasmonic materials, such as graphene, silicon, and metals themselves, our design leverages DNA not just as a structural element but as a dynamic enhancer of SHG due to its unparalleled photon absorption and interaction capabilities at the nanoscale. Through advanced DNA-based modeling and simulation, we introduce a novel nanoparticle architecture optimized to surpass current SHG efficiency benchmarks, without incorporating gas sensing functionalities. This breakthrough not only signifies a significant leap in the field of nonlinear optics but also opens new avenues for the application of biomolecular components in enhancing plasmonic phenomena.\u003c/p\u003e","manuscriptTitle":"Enhanced Second Harmonic Generation through DNA-Integrated Plasmonic Nanoparticles - A Novel Nonlinear Optical Approach","msid":"","msnumber":"","nonDraftVersions":[{"code":1,"date":"2024-11-06 08:06:35","doi":"10.21203/rs.3.rs-5336086/v1","editorialEvents":[{"type":"communityComments","content":0}],"status":"published","journal":{"display":true,"email":"[email protected]","identity":"researchsquare","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":true,"externalIdentity":"","sideBox":"","snPcode":"","submissionUrl":"/submission","title":"Research Square","twitterHandle":"researchsquare","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"","reportingPortfolio":"","inReviewEnabled":false,"inReviewRevisionsEnabled":true}}],"origin":"","ownerIdentity":"94f14c5d-d240-4a23-a02b-6b6b3929fa3f","owner":[],"postedDate":"November 6th, 2024","published":true,"recentEditorialEvents":[],"rejectedJournal":[],"revision":"","amendment":"","status":"posted","subjectAreas":[],"tags":[],"updatedAt":"2024-11-06T08:06:37+00:00","versionOfRecord":[],"versionCreatedAt":"2024-11-06 08:06:35","video":"","vorDoi":"","vorDoiUrl":"","workflowStages":[]},"version":"v1","identity":"rs-5336086","journalConfig":"researchsquare"},"__N_SSP":true},"page":"/article/[identity]/[[...version]]","query":{"redirect":"/article/rs-5336086","identity":"rs-5336086","version":["v1"]},"buildId":"qtupq5eGEP_6zYnWcrvyt","isFallback":false,"isExperimentalCompile":false,"dynamicIds":[84888],"gssp":true,"scriptLoader":[]}