The new clinical application of bilateral-contralateral cervix clamp in postpartum hemorrhage: a retrospective cohort study

Background: To assess the efficacy and safety of bilateral-contralateral cervix clamp firstly applied in postpartum hemorrhage caused by uterine tony of lower segment. Methods: Totally 47 pregnant women with postpartum hemorrhage secondary to lower uterine segment atony in vaginal delivery or after caesarean delivery were included from March 1, 2020 to May 31, 2020. According to patient’s informed consent, 22 women accepted cervical clamp to treat and 25 only used uterotonics in control group.Then hemostatic efficacy and safety of bilateral-contralateral cervix clamp were assessed by retrospective analysis. Results: It was found that mean blood loss in clamp group was much less during vaginal delivery (656.2±72.79g vs 811.8±86.07g, p=0.001) or after caesarean delivery (42.8±6.60g vs 126.3±86.97g, p=0.007), and incidence of uterotonic repeated usage (81.8% vs 36%, 18.2 % vs 64%, p=0.001) or side effect (18.2% vs 48.0%, p=0.031) appeared less than control group, but there was no statistical differences on hospital stay(4.1±1.57days vs 3.8±1.61days, p=0.535), hemoglobin(119±4.10g vs 121.4±4.19g, p=0.058)，blood transfusion(9.1% vs 12%,p=0.746), surgical procedures(4.5% vs 4.0%, p=0.93), also no clamp complications occurred. Conclusions: The bilateral-contralateral cervix clamp was effective and safe, this new technique could be a complementary treatment for postpartum hemorrhage.