Successful outcome following pre-viability amniorrhexis
A prolonged pre-viability spontaneous membrane rupture and anhydramnion in a patient with IVF-conceived pregnancy resulted in a healthy infant born at 28 weeks gestation.
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This paper reports a single case of a 34-year-old primigravida with severe bilateral tubal disease and grade IV endometriosis who conceived after multiple IVF embryo transfer attempts and then experienced spontaneous pre-viability rupture of membranes at 17 weeks. She chose expectant management despite the risks of prolonged preterm PROM and anhydramnios, and the pregnancy continued until 28 weeks, when delivery by emergency cesarean section was required due to major antepartum hemorrhage after placental abruption. The infant was born in good condition without features of oligohydramnios tetrad (Potter’s sequence, skeletal deformities, intrauterine growth restriction, and pulmonary hypoplasia). The paper’s limitation is that it is an individual case report, and it focuses on counseling/psychological support rather than establishing generalizable outcomes. This paper is centrally about endometriosis — the patient’s underlying grade IV endometriosis is described as part of the case context alongside the pre-viability amniorrhexis outcome.
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- europepmc
- last seen: 2026-09-12T06:55:35.949492+00:00
- pubmed
- last seen: 2026-05-13T22:15:06.633332+00:00
- unpaywall
- last seen: 2026-05-14T19:30:52.867331+00:00
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