Successful outcome following pre-viability amniorrhexis

case-report OA: closed public-domain-us
Full text JSON View on PubMed View at publisher
AI-generated summary by gemini-2.5-flash-lite, 2026-07-09

A prolonged pre-viability spontaneous membrane rupture and anhydramnion in a patient with IVF-conceived pregnancy resulted in a healthy infant born at 28 weeks gestation.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

AI-generated deep summary by claude@2026-07, 2026-07-09 · read from full text

This paper reports a single case of a 34-year-old primigravida with severe bilateral tubal disease and grade IV endometriosis who conceived after multiple IVF embryo transfer attempts and then experienced spontaneous pre-viability rupture of membranes at 17 weeks. She chose expectant management despite the risks of prolonged preterm PROM and anhydramnios, and the pregnancy continued until 28 weeks, when delivery by emergency cesarean section was required due to major antepartum hemorrhage after placental abruption. The infant was born in good condition without features of oligohydramnios tetrad (Potter’s sequence, skeletal deformities, intrauterine growth restriction, and pulmonary hypoplasia). The paper’s limitation is that it is an individual case report, and it focuses on counseling/psychological support rather than establishing generalizable outcomes. This paper is centrally about endometriosis — the patient’s underlying grade IV endometriosis is described as part of the case context alongside the pre-viability amniorrhexis outcome.

Read from the paper's body, not the abstract. Not a substitute for reading the paper. No clinical advice. How this works

Abstract

A 34-years-old primigravida conceived following a fourth attempt at in vitro fertilization and embryo transfer for severe bilateral tubal disease and grade IV endometriosis. Pregnancy progressed well until 17 weeks gestation when she spontaneously ruptured her membranes. She elected to continue with the pregnancy despite the significant risks associated with prolonged rupture of membranes (PROM) and anhydramnion at extremes of viability. Pregnancy was carried to 28 weeks gestation, when delivery was necessitated by a major antepartum haemorrhage following abruption placentae. A male infant weighing 1,100 g was delivered by emergency caesarean section in good condition, and with no features oligohydramnion tetrad (Potter's features, skeletal deformities, intrauterine growth restriction, and pulmonary hypoplasia). This case adds to the small number of cases in the literature of successful outcome following prolonged pre-viability PROM. Counselling and psychological support to the parents in this situation is extremely important since the anxiety and uncertainty associated with expectant management of PROM does not end with the "successful" delivery of the baby but persists all through the neonatal period and for several years later.
Full text 4,179 characters · extracted from oa-doi-fallback · 2 sections · click to expand

Abstract

A 34-years-old primigravida conceived following a fourth attempt at in vitro fertilization and embryo transfer for severe bilateral tubal disease and grade IV endometriosis. Pregnancy progressed well until 17 weeks gestation when she spontaneously ruptured her membranes. She elected to continue with the pregnancy despite the significant risks associated with prolonged rupture of membranes (PROM) and anhydramnion at extremes of viability. Pregnancy was carried to 28 weeks gestation, when delivery was necessitated by a major antepartum haemorrhage following abruption placentae. A male infant weighing 1,100 g was delivered by emergency caesarean section in good condition, and with no features oligohydramnion tetrad (Potter’s features, skeletal deformities, intrauterine growth restriction, and pulmonary hypoplasia). This case adds to the small number of cases in the literature of successful outcome following prolonged pre-viability PROM. Counselling and psychological support to the parents in this situation is extremely important since the anxiety and uncertainty associated with expectant management of PROM does not end with the “successful” delivery of the baby but persists all through the neonatal period and for several years later. Similar content being viewed by others

References

Papantoniou NE, Antsaklis AJ, Protopapas AG, Vogiatzi AI, Aravantinos DI (1997) Predictive value of amniotic fluid and fetal blood cultures in pregnancy outcome in preterm prelabour rupture of membranes. J Obstet Gynaecol 17(1):18–22 Hadi HA, Hodson CA, Strickland D (1994) Premature rupture of the membranes between 20 and 25 weeks’ gestation: role of amniotic fluid volume in perinatal outcome. Am J Obstet Gynecol 170(4):1139–1144 Stewart CJ, Tregoning SK, Moller G, Wainwright H (2005) Preterm prelabour rupture of the membranes before 28 weeks: better than feared outcome of expectant management in Africa. Eur J Obstet Gynecol Reprod Biol 126:186–192 Carroll SG, Ville Y, Greenough A, Gamsu H, Patel B, Philpott-Howard J, Nicolaides KH (1995) Preterm prelabour amniorrhexis: intrauterine infection and interval between membrane rupture and delivery. Arch Dis Child Fetal Neonatal Ed 72(1):43–46 Hnat MD, Mercer BM, Thurnau G, Goldenberg R, Thou EA, Meis PJ, Moawad AH, Iams JD, Van Dorsten JP (2005) Perinatal outcomes in women with preterm rupture of membranes between 24 and 32 weeks of gestation and a history of vaginal bleeding. Am J Obstet Gynecol 193(1):164–168 Major CA, de Veciana M, Lewis DF, Morgan MA (1995) Preterm premature rupture of membranes and abruptio placentae: is there an association between these pregnancy complications? Am J Obstet Gynecol 172(21):672–676 Rotschild A, Ling EW, Puterman ML, Farquharson D (1990) Neonatal outcome after prolonged preterm rupture of the membranes. Am J Obstet Gynecol 162(1):46–52 Marret H, Descamps P, Fignon A, Perrotin F, Body G, Lansac J (1998) Management of premature rupture of membranes in a monofetal pregnancy before 28 weeks gestation. J Gynecol Obstet Biol Reprod (Paris) Rev 27(7):665–675 Shumway JB, Al-Malta A, Amon E, Cohlan B, Amini S, Abboud M, Winn HN (1999) Impact of oligohydramnios on maternal and perinatal outcomes of spontaneous premature rupture of the membranes at 18–28 weeks. J Matern Fetal Med 8(1):20–23 Garite TJ (1985) Premature rupture of the membranes: the enigma of the obstetrician. Am J Obstet Gynecol 151(8):1001–1005 Kilbride HW, Yeast J, Thibeault DW (1996) Defining limits of survival: lethal pulmonary hypoplasia after midtrimester premature rupture of membranes. Am J Obstet Gynecol 175(31):675–681 Yang LC, Taylor DR, Kaufman HH, Hume R, Calhoun B (2004) Maternal and fetal outcomes of spontaneous preterm premature rupture of membranes. J Am Osteopath Assoc 104(12):537–542 Author information Authors and Affiliations Corresponding author Rights and permissions About this article Cite this article Engemise, S., Kalu, E. & Haque, K. Successful outcome following pre-viability amniorrhexis. Arch Gynecol Obstet 276, 87–89 (2007). https://doi.org/10.1007/s00404-006-0310-4 Received: Accepted: Published: Issue date: DOI: https://doi.org/10.1007/s00404-006-0310-4

Text is read by the "Ask this paper" AI Q&A widget below. Extraction quality varies by source — PMC NXML preserves structure cleanly, OA-HTML may include some navigation residue, and OA-PDF can have broken hyphenation. The publisher copy (via DOI) is the canonical version.

My notes (saved in your browser only)

Ask this paper AI returns verbatim quotes from the full text · source: oa-doi-fallback

Answers must be backed by verbatim quotes from this paper's full text. Hallucinated quotes are dropped automatically; if no verbatim passage answers the question, we say so. How this works

Condition tags

endometriosis

MeSH descriptors

Fetal Viability Premature Rupture of Fetal Membranes Adult Female Humans Live Birth Pregnancy Pregnancy Trimester, Second

Citation neighborhood (no data yet)

We don't have any in-corpus citations linked to this paper yet. The paper's references may be in our DB but unresolved to ``paper_id`` (resolution happens at ingest when the cited DOI matches a row we already have). Run the cross-source citation reconcile pass to retry.

Source provenance

europepmc
last seen: 2026-09-12T06:55:35.949492+00:00
pubmed
last seen: 2026-05-13T22:15:06.633332+00:00
unpaywall
last seen: 2026-05-14T19:30:52.867331+00:00
License: public-domain-us · commercial use OK · attribution required
Courtesy of the U.S. National Library of Medicine