Adenomyosis and endometrial receptivity: biological myth or clinical reality?

Paul Pirtea, Estelle Hagège, Jean Marc Ayoubi
In: Médecine de la Reproduction · 2026 · vol. 28(1) , pp. 85–88 · doi:10.1684/mte.2026.1085 · W7154737508
article OA: closed CC0
Full text JSON View on OpenAlex View at publisher
⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-06-08 ⓘ

Women with adenomyosis do not demonstrate impaired endometrial receptivity during euploid blastocyst transfer in hormone replacement cycles, despite molecular and inflammatory endometrial changes.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

⚙ AI-generated deep summary by claude@2026-06, 2026-06-10 · read from full text ⓘ

The paper reviews the proposed link between adenomyosis and endometrial receptivity, asking whether biological alterations are reflected as clinically meaningful changes during assisted reproduction. Using clinical evidence from assisted reproduction, it reports that data do not confirm an altered endometrial receptivity in adenomyosis when euploid blastocyst transfers are performed in hormone “substituted” cycles. It frames this as a discrepancy between documented molecular and inflammatory endometrial changes and the absence of clinically relevant receptivity impairment in the reported transfer setting. Relevance to endometriosis: the paper is centrally about adenomyosis and endometrial receptivity during frozen embryo (blastocyst) transfers, directly addressing how adenomyosis may affect receptivity.

Read from the paper's body, not the abstract. Not a substitute for reading the paper. No clinical advice. How this works

Abstract

Despite documented molecular and inflammatory alterations of the endometrium, clinical data from assisted reproductive technology do not support a meaningful impairment of endometrial receptivity in women with adenomyosis undergoing euploid blastocyst transfer in hormone replacement cycles.
Full text 734 characters · extracted from oa-doi-fallback · click to expand
Médecine de la Reproduction MENUAdénomyose et réceptivité endométriale : mythe biologique ou réalité clinique ? Volume 28, numéro 1, Janvier-Février-Mars 2026 Auteurs Hôpital Foch, Suresnes, France * Tirés à part : P. Pirtea, [email protected] - Mots-clés : réceptivité endométriale, adénomyose, transfert d’embryon congelé - DOI : 10.1684/mte.2026.1085 - Page(s) : 85-8 - Année de parution : 2026 Malgré l’existence d’altérations moléculaires et inflammatoires documentées de l’endomètre, les données cliniques issues de l’assistance médicale à la procréation ne confirment pas une altération cliniquement pertinente de la réceptivité endométriale dans l’adénomyose lors de transferts de blastocystes euploïdes en cycle substitué.

Text is read by the "Ask this paper" AI Q&A widget below. Extraction quality varies by source — PMC NXML preserves structure cleanly, OA-HTML may include some navigation residue, and OA-PDF can have broken hyphenation. The publisher copy (via DOI) is the canonical version.

My notes (saved in your browser only)

⚙ Ask this paper AI returns verbatim quotes from the full text · source: oa-doi-fallback ⓘ

Answers must be backed by verbatim quotes from this paper's full text. Hallucinated quotes are dropped automatically; if no verbatim passage answers the question, we say so. How this works

Condition tags

adenomyosis

Citation neighborhood (no data yet)

We don't have any in-corpus citations linked to this paper yet. This is a recent paper (2026) — citers typically take a year or two to land, and the OpenAlex reference graph may still be filling in.

Source provenance

openalex
last seen: 2026-06-10T17:14:06.276822+00:00
License: CC0 · commercial use OK