Research Progress on the Correlation Between Microecological Flora and Endometriosis

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This review article examines the correlation between microecological flora imbalances and the progression of endometriosis, a common estrogen-dependent disease characterized by ectopic endometrial growth. The authors highlight how dysbiosis in the intestinal and reproductive tracts can trigger local and systemic immune-inflammatory responses via cytokines and metabolic pathways, thereby influencing the disease's development. Consequently, the paper suggests that targeting microbial flora through specific interventions represents a promising therapeutic strategy for managing endometriosis. This paper is centrally about endometriosis — specifically focusing on the role of microbial dysbiosis in its pathogenesis and potential treatment avenues.

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Abstract

Microecological flora, an important part of the human microenvironment, changes with the changes in the internal and external environments of the human body, and plays an important role in maintaining human body's normal function. Endometriosis (EMs) is a common estrogen-dependent female disease chara-cterized by the growth of endometrial glands and mesenchyme outside the uterine cavity. Existing studies have shown that imbalance of intestinal and reproductive tract flora can trigger local immune-inflammatory responses and cause systemic immune-inflammatory responses through cytokines and metabolic pathways, which in turn participate in the progression of EMs. Thus, the diagnosis and treatment of EMs through microecological flora interventions is one of the hotspots research in this field. This article aims to review the research progress on the correlation between microbial dysbiosis and EMs, with the hope of providing more references for the treatment of EMs.
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Abstract: Microecological flora, an important part of the human microenvironment, changes with the changes in the internal and external environments of the human body, and plays an important role in maintaining human body's normal function. Endometriosis (EMs) is a common estrogen-dependent female disease chara-cterized by the growth of endometrial glands and mesenchyme outside the uterine cavity. Existing studies have shown that imbalance of intestinal and reproductive tract flora can trigger local immune-inflammatory responses and cause systemic immune-inflammatory responses through cytokines and metabolic pathways, which in turn participate in the progression of EMs. Thus, the diagnosis and treatment of EMs through microecological flora interventions is one of the hotspots research in this field. This article aims to review the research progress on the correlation between microbial dysbiosis and EMs, with the hope of providing more references for the treatment of EMs.

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endometriosis

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last seen: 2026-05-11T08:19:38.329619+00:00
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