Percutaneous Coronary Intervention in Diabetic versus Non-diabetic Patients with Prior Coronary Artery Bypass Grafting: A Propensity Score Matching Study

Percutaneous Coronary Intervention in Diabetic versus Non-diabetic Patients with Prior Coronary Artery Bypass Grafting: A Propensity Score Matching Study | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Help Center Sign In Submit a Preprint Cite Share Download PDF Research article Percutaneous Coronary Intervention in Diabetic versus Non-diabetic Patients with Prior Coronary Artery Bypass Grafting: A Propensity Score Matching Study Xiaolong Ma, Ran Dong, Pengfei Chen, Yichen Zhao, Caiwu Zeng, and 3 more This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.2.15663/v3 This work is licensed under a CC BY 4.0 License Status: Published Journal Publication published 06 Apr, 2020 Read the published version in BMC Cardiovascular Disorders → Version 3 posted 9 You are reading this latest preprint version Show more versions Abstract Background: The target of this study was to explore the outcomes of percutaneous coronary intervention (PCI) in diabetic versus non-diabetic patients with prior coronary artery bypass grafting (CABG) surgery. Methods: Seven hundred and twenty four patients who had previously received CABG and had been treated using PCI combined with drug-eluting stents (DES) between 2009 and 2017 were selected for a retrospective study and allocated into either a diabetes mellitus (DM) or non-diabetes mellitus (No DM) group. A 1:1 propensity score-matched evaluation was conducted and risk adjusted for analysis. The primary outcomes were cardiac death, myocardial infarction, heart failure and revascularization, with a median follow-up duration of 5.13 years. Results: After matching, two-, 5- and 8-year event rate of overall major adverse cardiac events (MACEs) were found to be higher in the DM group (No DM vs DM:15.3%, 30.9%, 38.5% vs 19.8%, 37.8%, 52.2%, respectively), although no significant difference was found in the event rate of overall MACEs (hazard ratio [HR]: 1.35; 95% confidence interval [CI]: 1.00 to 1.83 for DM vs No DM; P=0.052), cardiac death (HR: 0.94; 95% CI: 0.45 to 1.95; P=0.871), MI (HR: 1.49; 95% CI: 0.95 to 2.32; P=0.080), HF (HR: 1.54; 95% CI: 0.90 to 2.63 for; P=0.120) or revascularization (HR: 1.07; 95% CI: 0.72 to 1.59; P=0.747). Subgroup analysis of PCI in only the NCA showed MACEs (adjusted HR: 1.13; 95% CI: 0.85 to 1.49 for DM vs No DM; P=0.325), cardiac death (adjusted HR: 0.85; 95% CI: 0.41 to 1.78 for DM vs No DM; P=0.781), MI (adjusted HR: 1.32; 95% CI: 0.84 to 2.01 for DM vs No DM; P=0.069), HF (adjusted HR: 1.41; 95% CI: 0.87 to 2.27 for DM vs No DM; P=0.211) or repeated revascularization (adjusted HR: 0.93; 95% CI: 0.64 to 1.37 for DM vs No DM; P=0.836). Conclusions : Compared with non-diabetic patients with prior CABG, subsequent implantation of DES in the native coronary artery of diabetic patients resulted in apparently similar outcomes. Trial registration : This study was not registered in an open access database. Key Words: Percutaneous coronary intervention; Diabetic; Non-diabetic; Coronary artery bypass grafting. Cardiac & Cardiovascular Systems Cardiothoracic Surgery Percutaneous coronary intervention Diabetic Non-diabetic Prior Coronary artery bypass grafting Outcomes. Figures Figure 1 Figure 2 Figure 3 Figure 4 Background Diabetic patients have a higher prevalence of coronary artery disease (CAD) than the general population, manifesting as diffuse lesions and severe atherosclerosis in the left main artery and multiple other vessels [1] , severe symptoms often developing earlier in life combined with a substantially poorer prognosis than non-diabetic patients [2,3] . It has been reported that diabetes is considered a predictor of adverse events such as myocardial infarction (MI), repeat revascularization and cardiac death for patients who have undergone coronary artery bypass grafting (CABG) [4–6] . For patients with prior CABG who require repeat revascularization, percutaneous coronary intervention (PCI) is usually the preferred strategy, rather than redo CABG, because of the low procedural mortality and similar long-term outcome [7-8] , combined with placement o f a drug-eluting stent (DES) [9] . Despite a number of studies investigating the impact that diabetes has on the clinical outcome of PCI with DES in patients without prior CABG [10-11] , little is known about the influence of diabetes on outcomes of PCI with DES in patients who have previously undergone CABG. In this study, we retrospectively assessed the clinical data of non-diabetic and diabetic patients with prior CABG who had subsequently received PCI with DES, aiming to establish the impact of DM on the long-term outcomes of PCI for restenosis after CABG. Methods Study design: This study was a retrospective observational study conducted in Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart Lung and Blood Vessel Diseases, Beijing, China. A total of 724 patients with prior CABG were selected from the institution's PCI registry (2009 to 2017) who had undergone PCI with DES in a native coronary artery (NCA), following CABG surgery for coronary atherosclerotic heart disease in the same hospital. Patients were segregated into a diabetes mellitus (DM) or non-diabetes mellitus (No DM) group, according to whether or not they suffered from DM. All data were reviewed by one cardiac surgeon and two cardiologists, the latter contacting patients for follow-up outcomes by telephone, mail or visit. The study was approved by the Institutional Ethics Committee of Beijing Anzhen Hospital. Definitions used in this study Patients’ data before PCI was defined as baseline data. DM was defined as either a previous diagnosis of DM treated with diet, oral agents, peptide analogs or insulin, or a new diagnosis after index hospitalization [12] before PCI. A graft with a stenosis of >70% of its diameter was defined as stenosis. A graft with stenosis or occlusion was classified as a diseased graft in this study. The classification of ischemic territory was based on the results of coronary angiography (CAG) after re-hospitalization and also referred to the results prior to CABG. NCA related to ischemic territory was defined as relevant NCA. Paclitaxel-eluting and sirolimus-eluting stents were defined as first-generation DES. Everolimus-eluting and zotarolimus-eluting stents were defined as second-generation DES. Procedural complications refer to complications post PCI. PCI failure was defined as failure to implant a stent at one lesion site. The primary end-point was a major adverse cardiac event (MACE), defined as the combined incidence of either cardiac death, myocardial infarction (MI), heart failure (HF) or revascularization, as independently adjudicated by an events committee. Cardiac death was defined as any death due to MI, HF, lethal arrhythmia or sudden death in a previously stable patient [13] . MI was defined as: (1) elevation of myocardial enzymes such as cardiac troponin T (cTnT) or creatine kinase-muscle/brain (CK-MB) >2 fold higher than the upper normal value and (2) changes in ST-segment and T-wave (ST-T) on electrocardiography [14] . HF was defined as hospitalization for progressive heart failure with clinical and radiographic signs. Revascularization was defined as undergoing a subsequent revascularization procedure by PCI or Redo CABG after discharge from the Department of Cardiology, Anzhen Hospital. Statistical analysis All results were analyzed using Stata SE for Windows, version 15.0 (Stata Corporation, College Station, TX, USA) statistical package and IBM SPSS Statistics for Windows, version 22.0. Categorical variables are presented as raw numbers (%) and continuous variables as means ± standard deviation. Comparisons of the DM and No DM groups were accomplished using a Fisher’s exact test for each variable and Mann-Whitney-Wilcox nonparametric test for continuous variables. To reduce the impact of potential confounding on MACEs on the results of the observational study, 1:1 propensity score matching was conducted to choose patients with comparable baseline data. After evaluation of covariates associated clinically and / or statistically with the treatment group and removal of repeatedly defined or collinear variables, including baseline characteristics, risk factors, medical history, clinical conditions at admission and treatment during hospitalization, 36 variables listed in Figure 2 were included in the propensity score matching model using greedy nearest neighbor matching without replacement and a caliper of 0.02. The absolute standardized difference in variables included for the calculation of propensity score were compared before and after propensity-score matching. The absolute standardized difference cut-off point for the variables included in the calculation was fixed at 10.0%. After matching, Cox proportional hazards regression analysis was also conducted to assess the association between variables and follow-up outcomes. Univariable Cox proportional hazards regression models were initially conducted, followed by multivariable Cox proportional hazards regression models. The candidate variables were potential confounding variables that were either mostly included in the propensity score matching model or reported more than once with an effect on cardiac death or MACEs. After forward stepwise selection with inclusion criteria both set at P=0.2, the variables were eventually included in multivariable Cox proportional hazards regression models of cardiac death and MACEs, respectively. Outcomes were compared using a log-rank test and presented as Kaplan-Meier curves. For all analyses reported, P values were 2-sided. Statistical differences were considered significant for values of P ＜0.05. Results Baseline characteristics In this study, 724 patients were included of which 351 patients (48.5%) exhibited DM. In the DM group, 43.3% of patients presented between 1 and 5 years after CABG and 33.0% between 5 and 10 years, as shown in Figure 1. The absolute standardized difference values before and after matching are shown in Figure 2. Following the matching, absolute standardized differences < 10.0% for those variables included indicated a relatively small imbalance. The baseline characteristics are shown in Table 1. After matching, there were 256 patients in each group, and the statistical difference in age (years), BMI, duration of period after CABG, numbers of patients that were ＞65 years old, had chronic lung disease, prior cerebrovascular accidents (CVA) or prior PCI were not as significant as they had been before matching the two groups. The characteristics of the CAGs of the diseased grafts and relevant NCAs are also shown in Table 1, with no significant difference between the two groups before matching. The relevant indicators of blood sugar of patients such as glucose concentratrion and glycosylated hemoglobin (HbA1c) are also shown in Table 1. PCI-related baseline characteristics Table 2 displays the procedural baseline characteristics, which are also included in the propensity score matching. After matching, PCI was mostly performed in NCA only (No DM: 87.1% vs DM: 87.9%) with first-generation DES used widely (No DM: 62.1% vs DM: 64.8%) in each group. A small proportion of patients also underwent percutaneous coronary angioplasty (PTCA) in addition to stent implantation (No DM: 7.4% vs DM: 9.0%) and PCI failure in stent implantation in one lesion site (No DM: 4.3% vs DM: 5.1%). EPD, rotational atherectomy, aspiration of thrombus or intravascular ultrasound (IVUS) were not greatly used in either group. Procedural complications Table 3 describes recorded procedural complications. After matching, the DM group exhibited slightly high in-hospital mortality, with a higher incidence of angina after 24h (5.1%), periprocedural MI (1.2%), stroke (0.8%) and bleeding (1.6%), but there was no significant difference between the two groups. Follow-up outcomes Complete follow-up data were obtained in the overall study population, as displayed in Table 4 and Figure 3. The median follow-up duration was 5.13 years. After matching, Kaplan-Meier curves (Figure 4 A) indicated that the cumulative overall rate of MACEs was higher in the DM group at 2 years (No DM: 15.3% vs DM: 19.8%), 5 years (No DM: 30.9% vs DM: 37.8%) and at 8 years (No DM: 38.5% vs DM: 52.2%) (hazard ratio [HR]: 1.35; 95% confidence interval [CI]: 1.00 to 1.83 for DM vs No DM; P=0.052), with an apparent increase in the difference between the two groups over time. The curves indicated that two-, 5- and 8-year incidence of cardiac death in each group (Figure 4 B) were similar (No DM: 1.6%, 5.8%, 10.5% vs DM 1.2%, 5.8%, 9.3%; HR: 0.94; 95% CI: 0.45 to 1.95 for DM vs No DM; P=0.871). There was also no statistical difference in incidence of MI (HR: 1.49; 95% CI: 0.95 to 2.32 for DM vs No DM; P=0.080), HF (HR: 1.54; 95% CI: 0.90 to 2.63 for DM vs No DM; P=0.120) or repeated revascularization (HR: 1.07; 95% CI: 0.72 to 1.59 for DM vs No DM; P=0.747) between the two groups, although there was a trend that the incidence of MI or HF in the DM group increased over time. Multivariable Cox proportional hazards regression (Figure 4) demonstrated that patients with hypertension (adjusted HR: 1.85; 95% CI: 1.32 to 2.59; P＜0.001), aspiration of thrombus during PCI (adjusted HR: 3.37; 95% CI: 1.05 to 10.84; P=0.041), prior HF (adjusted HR: 4.30; 95% CI: 1.82 to 10.14; P=0.001) or LVEF＜50% (adjusted HR: 1.52; 95% CI: 1.07 to 2.17; P=0.020) were more likely to suffer a MACE. Additionally, use of a statin provided protection from MACEs (adjusted HR: 0.57; 95% CI: 0.41 to 0.78; P=0.001). Subgroup analysis of PCI in different target vessels To reduce the influence of PCI in different target vessels, we performed two additional subgroup analyses of patients that had undergone PCI only in the NCA or PCI in both the NCA and graft. The baseline characteristics of the two subgroups are detailed within Additional File 1: Tables S1, S2 and S3. The follow-up outcomes of the two subgroups are provided separately in Tables S4, S5 and Figures S1, S2. The follow-up outcomes of patients that underwent PCI in only the NCA were consistent with all clinical endpoints experienced by the whole population. Compared with the non-diabetic patients who had previously undergone CABG, subsequent PCI in only the NCA in diabetic patients appeared to result in similar outcomes (Table S4, Figure S1), including MACEs (adjusted HR: 1.13; 95% CI: 0.85 to 1.49 for DM vs No DM; P=0.325), cardiac death (adjusted HR: 0.85; 95% CI: 0.41 to 1.78 for DM vs No DM; P=0.781), MI (adjusted HR: 1.32; 95% CI: 0.84 to 2.01 for DM vs No DM; P=0.069), HF (adjusted HR: 1.41; 95% CI: 0.87 to 2.27 for DM vs No DM; P=0.211) or repeated revascularization (adjusted HR: 0.93; 95% CI: 0.64 to 1.37 for DM vs No DM; P=0.836). When it came to the follow-up outcomes of patients with PCI in both the NCA and graft (Table S5, Figure S2), diabetic patients with subsequent PCI in both the NCA and graft were more likely to experience MACEs (adjusted HR: 4.00; 95% CI: 1.67 to 9.58 for DM vs No DM; P=0.003), cardiac death (adjusted HR: 16.04; 95% CI: 1.58 to 162.50 for DM vs No DM; P=0.066), MI (adjusted HR: 3.78; 95% CI: 1.29 to 11.06 for DM vs No DM; P=0.010), HF (adjusted HR: 7.61; 95% CI: 1.06 to 54.57 for DM vs No DM; P=0.091) or repeated revascularization (adjusted HR: 3.36; 95% CI: 1.05 to 10.68 for DM vs No DM; P=0.276). Subgroup analysis of PCI with different generation DESs To reduce the influence of PCI with different generation DESs, we performed two additional subgroup analyses of patients that had undergone PCI with first-generation DESs or second-generation DESs. The baseline characteristics of the two subgroups are detailed within Additional File 1: Tables S6, S7 and S8. The follow-up outcomes of the two subgroups are provided separately in Tables S9, S10 and Figures S3, S4. The follow-up outcomes of patients that underwent PCI with first-generation DESs were consistent with all clinical endpoints experienced by the whole population. Compared with the non-diabetic patients who had previously undergone CABG, subsequent PCI with first-generation DESs in diabetic patients appeared to result in similar outcomes (Table S9, Figure S3). When it came to the follow-up outcomes of patients with PCI with second-generation DESs (Table S10, Figure S4), diabetic patients with subsequent PCI with second-generation DESs were more likely to experience MACEs (adjusted HR: 1.76; 95% CI: 1.00 to 3.08 for DM vs No DM; P=0.016), MI (adjusted HR: 1.90; 95% CI: 0.75 to 4.81 for DM vs No DM; P=0.038) and HF (adjusted HR: 1.87; 95% CI: 0.72 to 4.89 for DM vs No DM; P=0.018). The outcomes of cardiac death (adjusted HR: 1.10; 95% CI: 0.01 to 1.47 for DM vs No DM; P=0.852) and repeated revascularization (adjusted HR: 1.67; 95% CI: 0.79 to 3.53 for DM vs No DM; P=0.305) are similar between two groups. Follow-up outcomes of patients with incomplete revascularization vs complete revascularization We reviewed the coronary angiography files, 37 patients (5.1%) received incomplete revascularization (IR) by PCI and 687 patients (94.9%) received complete revascularization (CR) by PCI after CABG. Follow-up outcomes of patients with IR vs CR are shown in Table S11. Compared with patients with CR, patients with IR are more likely to have MACEs (40.5% vs 33.0%), cardiac death (8.1% vs 4.8%) and MI (21.6% vs 14.1%), though there are no significant differences between two groups. Discussion We performed a retrospective observational study to explore the outcomes of PCI with DES in diabetic vs non-diabetic patients who had previously undergone CABG in our single-center registry. We found that, compared to non-diabetic patients with prior CABG, subsequent PCI within the NCA with DES in diabetic patients appeared to result in a similar overall incidence of MACEs, cardiac death, MI, HF or repeated revascularization, extending our current understanding of the safety and efficacy of DES even in high-risk patients with prior CABG. This suggests that a DES may be considered the default option in these patient populations. In this study we also found that hypertension, prior HF, LVEF＜50% and aspiration of thrombus are predictive of overall MACEs and patients taking statins are less likely to experience MACEs. Our results were based on matching propensity scores, which suggests that our findings are not due to negative confounding. Diabetic patients with CAD are reported to have dysfunctional endothelial cells, increased atherosclerotic burden and fragile lipid-rich plaques [15,16] , microcirculation disorder involving smaller vessels, and prothrombotic and proinflammatory states [17-18] , which are related to progression of NCA disease. It is confirmed that CAD in diabetic patients appears as diffuse atherosclerosis with chronic total occlusion (CTO), opening and bifurcation lesions or multivessel disease and left main disease [19] , leading to fewer amenable options for re-intervention and suboptimal stent expansion [20] . In this study, although the characteristics of the lesions in the NCAs relevant to ischemic territory are similar in both diabetic and non-diabetic patients, those in each group represent a high proportion of the CTO lesions, openings involving lesions, branches involving lesions or diffuse lesions. We consider that this is due to the combined CAD risk factors, such as hypertension, dyslipidemia, diabetes mellitus, fat, smoking and gender. In order to remove the influence of confounding CAD risk factors and to compare between the DM group and No DM group more precisely, we used the propensity score matching method, described in detail in the statistical analysis section. Atherosclerosis is also reported to play an important role in later graft failure (graft age ＞6 months) [20] . Graft atherosclerosis in diabetic patients has a larger necrotic core with unstable plaques [21] , which is friable and more prone to distal coronary embolization [2] . Compared with non-diabetic patients with prior CABG, diabetic patients have a higher rate of graft stenosis and recurrent myocardial ischemic events [22, 23] , due to the progression of NCA disease or graft failure [2] . In this study the majority of patients in each group had diseased grafts (81.2% and 79.2% in the No DM and DM groups, respectively), and a small proportion of the remaining patients in each group had myocardial ischema caused by isolated NCA lesions as a consequence of the progression of NCA disease (18.8% and 20.8% in the No DM and DM groups, respectively). DES are superior to bare metal stents (BMS), in terms of their strut thickness and polymer coating composition, reducing repeat revascularization and in-stent thrombosis in addition to MI in non-diabetic patients [19] . Published literature indicates that PCI with DES in diabetic patients compared with non-diabetic patients results in significantly higher mortality, reinfarction, and repeat revascularization for in-stent restenosis [24-26] . The pathological mechanism of in-stent restenosis in diabetic patients is associated with excessive endothelial hyperplasia, vascular remodeling or increased platelet aggregation [27] . However, in this study we found different results, especially when performing additional subgroup analysis of patients with PCI in only the NCA, in that PCI in the NCA with DES in diabetic patients compared with non-diabetic patients did not result in a high incidence of cardiac death, HF or repeat revascularization, and the incidence of MI between the two groups was not significantly different. However, one key observation should be clearly noted, that patients in that study included those without prior CABG. Conversely, all patients included in this study underwent prior CABG in our cardiac center, which could be considered a pretreatment for diabetic patients and functions as protection. In addition, all were high risk patients, especially in the DM group. They were older with a greater number of comorbidities and had severe NCA or graft lesions. The studies of Ahmed [28] and Ashfaq [ 29] reported the influence of DM on outcomes in saphenous vein graft (SVG) stenting, with similar conclusions, that PCI with DES in diabetics resulted in long-term overall rates of MACEs, death, MI and repeat revascularization that were worse than in non-diabetics, quite different from Pendyala’s conclusion that diabetic patients undergoing SVG PCI had similar long-term outcomes [27] . In the present study, after analysis of the whole study population (after matching, n=512), we found that the overall incidence of MACEs (DM: 37.5% vs No DM: 29.3%), principally driven by MI (DM: 18.4% vs No DM: 12.9%), were not statistically different between the two groups despite an increasing trend over time. Considering the conflicting data of all the patients that received PCI in the NCA and that a minority of patients were treated with PCI in both graft and NCA (No DM: 12.9% vs DM: 12.1), we performed further subgroup analysis of patients with PCI in only the NCA (n=635). We found that, compared to non-diabetic patients with prior CABG, subsequent DES in only the NCA of diabetic patients appeared to result in similar outcomes, such as rates of MACEs, cardiac death, MI, HF and repeat revascularization. Additional subgroup analysis of patients with PCI in both the NCA and graft, despite the small sample size of patients in this subgroup (n=89), demonstrated that, compared to non-diabetic patients with prior CABG, subsequent DES in the NCA and grafts of diabetic patients resulted in worse outcomes, consistent with Ahmed and Ashfaq’s studies. According to the 2018 ESC/EACTS Guidelines for myocardial revascularization [2] , it is recommended that PCI in the NCA should be considered rather than PCI in an SVG graft, because that is associated with a high risk of periprocedural MI [30] and worse long-term outcomes such as all-cause death, MI or revascularization [31] for no-reflow, subsequent in-stent restenosis, distant target lesions and excessive tortuosity [8] , especially for PCI in an SVG of a diabetic patient for graft atherosclerosis with a larger necrotic core and friable plaques [21] . In this study, we also provided follow-up outcomes of patients with IR vs CR by PCI. Achieving CR of all significantly obstructed coronary artery has been an established goal of PCI, and more recent data demonstrate a salutary effect of CR following PCI on long-term outcomes. IR is associated with increased mortality following PCI, as well as with an increased incidence of MI, repeat revascularization, and MACCEs [32] . Though, in our study the sample size of patients with IR was too small (5.1%), which would influence statistical results,, we still believed that it made a little sense, compared with patients with CR, patients with IR were more likely to have MACEs (40.5%), cardiac death (8.1%) and MI (21.6%), though there were no significant difference between two groups. Further randomized controlled trial study with a larger sample size and longer follow-up may be required for patient with prior CABG. Limitations Firstly, this was a retrospective observational single-center study and so is subject to all the limitations of observational single-center studies, such as patient selection and a single therapeutic method, which might affect the results. Secondly, the angiography film results were analyzed by one cardiac surgeon and one cardiologist. Thirdly, the classification of graft lesions was in reference to the evaluation criteria of native vessels. Fourthly, the decision to perform PCI for each patient was taken by 2 operators, mostly based on an evaluation of the CAG results. Fifthly, 6 non-DM patients who had diabetes during the follow-up period were excluded from this study. Sixthly, we didn’t do PS matching for sub-group analysis. Despite these limitations, the results were derived from the largest angiographic study in patients with prior CABG so far published. In addition, the statistical analyses utilized rigorous methodology. Conclusions Compared to non-diabetic patients with prior CABG, subsequent PCI in an NCA with DES in diabetic patients appears to result in a similar incidence of overall MACEs, cardiac death, MI, HF and repeated revascularization, suggesting that DES may be considered the default option for these patient populations. We also found that hypertension, prior HF, LVEF＜50% and aspiration of thrombus are predictive for overall rate of MACE in diabetic patients with prior CABG. Patients that were administered statins were less likely to experience MACEs. List Of Abbreviations AHF: acute heart failure; AMI: acute myocardial infarction; BMI: body mass index; CABG: coronary artery bypass graft; CTO: chronic total occlusion; CVA: cerebrovascular accident; DES: drug-eluting stent ; DM: diabetes mellitus; HbA1c: glycosylated hemoglobin; HF: heart failure; LVEF: left ventricular ejection fraction; NCA: native coronary artery; MACEs: major adverse cardiac events; PCI: percutaneous coronary intervention; PVD: peripheral vascular disease; SA: stable angina; SVG: saphenous vein graft ; UA: unstable angina. Declarations Ethics approval and consent to participate Not applicable. Consent for publication Not applicable. Availability of data and materials The datasets generated and analyzed for this current study are available from the corresponding author upon reasonable request. Competing interests All authors declare that they have no competing interests. Funding This study was supported by grants from the National Natural Science Foundation of China (81370294, 81570291, 81770320). Professor Jiangang Wang owned the funding, a member of designers of this study. Authors' contributions The most important acknowledgment is to the participants in the study at Anzhen Hospital. JG W obtained funding. JG W, XL M, and R D designed the study. PF C, YC Z, CW Z, M X and Q Y collected and analyzed the data. XL M drafted the manuscript. All authors have read and approved the manuscript. Acknowledgements Not applicable References [1] O’Donoghue ML, Vaidya A, Afsal R, et al. An invasive or conservative strategy in patients with diabetes mellitus and non-ST-segment elevation acute coronary syndromes: A collaborative meta-analysis of randomized trials. J Am Coll Cardiol 2012;60:106–111. 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Vascular structural and functional changes in type 2 diabetes mellitus: evidence for the roles of abnormal myogenic responsiveness and dyslipidemia. Circulation 2002;106:3037-43. [18] Haffner SM, Lehto S, Rönnemaa T, et al. Mortality from coronary heart disease in subjects with type 2 diabetes and in nondiabetic subjects with and without prior myocardial infarction. N Engl J Med 1998;339:229-34. [19] Guandalini GS, Bangalore S. The Potential Effects of New Stent Platforms for Coronary Revascularization in Patients with Diabetes. Can J Cardiol 2018;34(5):653-664. [20] Scarsini R, Zivelonghi C, Pesarini G, et al. Repeat revascularization: Percutaneous coronary intervention after coronary artery bypass graft surgery. Cardiovasc Revasc Med 2016 ;17(4):272-8. [21] Baars T, Konorza T, Kahlert P, et al. Coronary aspirate TNF α reflects saphenous vein bypass graft restenosis risk in diabetic patients. Cardiovasc Diabetol 2013;12:12. [22] Detre KM, Lombardero MS, Brooks MM, et al. The effect of previous coronary-artery bypass surgery on the prognosis of patients with diabetes who have acute myocardial infarction. Bypass Angioplasty Revascularization Investigation Investigators. N Engl J Med 2000;342(14):989-97. [23] The BARI Investigators. Influence of diabetes on 5-year mortality and morbidity in a randomized trial comparing CABG and PTCA in patients with multivessel disease: The Bypass Angioplasty Revascularization Investigation (BARI).Circulation 1997;96:1761–1769. [24] Tailakh MA, Friger M, Zahger D, et al. Prospective study of the impact of diabetes mellitus newly diagnosed by glycated hemoglobin on outcomes in patients undergoing percutaneous coronary intervention. Eur J Intern Med 2017;37:69-74. [25] De Luca G, Dirksen MT, Spaulding C, et al. Impact of diabetes on long-term outcome after primary angioplasty: insights from the DESERT cooperation. Diabetes Care 2013;36(4):1020-5.. [26] Wang H, Gao Z, Song Y, et al. Impact of Diabetes Mellitus on Percutaneous Coronary Intervention in Chinese Patients: A Large Single-Center Data. Angiology 2018;69(6):540-547. [27] Pendyala LK, Loh JP, Kitabata H, et al. The impact of diabetes mellitus on long-term clinical outcomes after percutaneous coronary saphenous vein graft interventions in the drug-eluting stent era. J Interv Cardiol 2014;27(4):391-8. [28] Ahmed JM, Hong MK, Mehran R, et al. Influence of diabetes mellitus on early and late clinical outcomes in saphenous vein graft stenting. J Am Coll Cardiol 2000; 36(4):1186-93 [29] Ashfaq S, Ghazzal Z, Douglas JS, et al. Impact of diabetes on five-year outcomes after vein graft interventions performed prior to the drug-eluting stent era. J Invasive Cardiol 2006;18(3):100-5. [30] Coolong A, Baim DS, Kuntz RE, et al. Saphenous vein graft stenting and major adverse cardiac events: A predictive model derived from a pooled analysis of 3958 patients. Circulation 2008;117:790–797. [31] Brilakis E S , O'Donnell C I , Penny W , et al. Percutaneous Coronary Intervention in Native Coronary Arteries Versus Bypass Grafts in Patients With Prior Coronary Artery Bypass Graft Surgery: Insights From the Veterans Affairs Clinical Assessment, Reporting, and Tracking Program. JACC Cardiovasc Interv 2016, 9(9):884-893. [32] Kereiakes DJ.Reassessing the importance of complete versus incomplete coronary revascularization.Rev Cardiovasc Med 2014,15(1):24-30. Tables Table 1 Comparison of baseline characteristics of non-diabetic vs diabetic patients with prior CABG (n=724). Variable Unmatched Matched No DM DM P value No DM DM P value n=373 n=351 n=256 n=256 Demographics Age(year) 61.52 ± 9.23 63.64 ± 8.15 0.001 62.25 ± 8.71 62.86 ± 8.13 0.409 ≥65 years 146(39.1%) 165(47.0%) 0.036 101(39.5%) 108(42.2%) 0.590 Sex(Male) 290(77.7%) 261(74.4%) 0.296 192(75.0%) 197(77.0%) 0.679 Comorbidities Hypertension 263(70.5%) 268(76.4%) 0.078 188(73.4%) 192(75.0%) 0.762 Dyslipidemia 167(44.8%) 182(51.9%) 0.063 131(51.2%) 127(49.6%)) 0.791 Chronic renal disease 12(3.2%) 16(4.6%) 0.441 10(3.9%) 6(2.3%) 0.447 Chronic lung disease 20(5.4%) 8(2.3%) 0.035 10(3.9%) 8(3.1%) 0.811 Prior PVD 43(11.5%) 34(9.7%) 0.470 24(9.4%) 27(10.5%) 0.768 Prior CVA 49(13.1%) 66(18.8%) 0.042 40(15.6%) 37(14.5%) 0.805 Prior MI 52(13.9%) 75(21.4%) 0.011 43(16.8%) 40(15.6%) 0.811 Prior HF 6(1.6%) 2(0.6%) 0.288 3(1.2%) 2(0.8%) 1.000 Prior PCI 14(3.8%) 26(7.4%) 0.035 13(5.1%) 14(5.5%) 1.000 Smoking 238(63.8%) 212(60.4%) 0.358 162(63.3%) 167(65.2%) 0.712 BMI 25.70 ± 3.00 26.19 ± 3.18 0.037 25.97 ± 2.98 25.96 ± 3.23 0.965 HbA1c(%) 6.02 ± 1.08 7.50 ± 1.68 ＜ 0.001 5.97 ± 1.01 7.48 ± 1.37 ＜ 0.001 Blood sugar(mmol/L) 5.59 ± 1.46 7.89 ± 3.04 ＜ 0.001 5.43 ± 0.83 7.86 ± 2.77 ＜ 0.001 Symptoms 0.245 0.811 Chest pain 356(95.4%) 341(97.2%) 0.456 248(96.9%) 246(96.1%) 0.966 SA 142(39.9%) 126(37.0%) 98(39.5%) 96(39.0%) UA 133(37.4%) 124(36.4%) 90(36.3%) 92(37.4%) AMI 81(22.8%) 91(26.7%) 60(24.2%) 58(23.6%) Others 17(4.6%) 10(2.8%) 8(3.1%) 10(3.9%) Mean LVEF% 59.13 ± 9.16 58.46 ± 9.29 0.364 59.06 ± 8.96 58.65 ± 9.03 0.631 Duration after CABG 4.48 ± 3.43 5.03 ± 3.66 0.034 4.68 ± 3.43 4.71 ± 3.52 0.917 CAG characteristics Diseased graft 303(81.2%) 278(79.2%) 0.514 207(80.9%) 207(80.9%) 1.000 Relevant NCAs CTO 194(52.0%) 176(50.1%) 0.655 128(50.0%) 127(49.6%) 1.000 Diffuse lesions 56(15.0%) 53(15.1%) 1.000 38(14.8%) 37(14.5%) 1.000 Branches involved 104(27.9%) 114(32.5%) 0.195 70(27.3%) 73(28.5%) 0.844 Opening involved 117(31.4%) 106(30.2%) 81(31.6%) 81(31.6%) 1.000 Ischemic territory 0.885 0.649 One territory 142(38.1%) 137(39.0%) 102(39.8%) 99(38.7%) Two territories 172(46.1%) 163(46.4%) 125(48.8%) 121 (47.3%) Three territories 59(15.8%) 51(14.5%) 29(11.3%) 36(14.1%) SYNTAX Score I 42.0 ± 13.0 43.4 ± 12.7 0.145 42.1 ± 13.1 42.8 ± 12.9 0.575 AMI=acute myocardial infarction; BMI=body mass index; CABG=coronary artery bypass graft ; CTO=chroni c total occlusion; CVA=cerebrovascular accident; DM= diabetes mellitus; HbA1c= glycosylated hemoglobin; HF=heart failure; LVEF= left ventricular ejection fraction; NCA=native coronary artery PCI= percutaneous coronary intervention ; PVD=peripheral vascular disease; SA=stable angina; SVG= saphenous vein graft ; UA=unstable angina . Table 2 Procedural baseline characteristics of patients with prior CABG (n=724). Variable Unmatched Matched No DM DM P value No DM DM P value n=373 n=351 n=256 n=256 Femoral access 201(53.9%) 185(52.7%) 0.766 138(53.9%) 132(51.6%) 0.658 Target vessel 1.000 0.894 NCA only 327(87.7%) 308(87.7%) 223(87.1%) 225(87.9%) NCA and Graft 46(12.3%) 43(12.3%) 35(12.9%) 32(12.1%) Multi-vessel PCI 122(32.7%) 90(25.6%) 0.041 73(28.5%) 70(27.3%) 0.844 Stent Mean number of stents 1.88 ± 1.13 1.87 ± 1.09 0.874 1.83 ± 1.11 1.89 ± 1.12 0.558 First-generation DES 236(63.3%) 220(62.7%) 0.878 159(62.1%) 166(64.8%) 0.582 Second-generation DES 159(42.6%) 147(41.9%) 0.880 107(41.8%) 106(41.4%) 1.000 PTCA 40(10.7%) 30(8.5%) 0.379 19(7.4%) 23(9.0%) 0.629 PCI failure 18(4.8%) 19(5.4%) 0.739 11(4.3%) 12(5.1%) 0.835 EPD 12(3.2%) 5(1.4%) 0.142 5(2.0%) 4(1.6%) 1.000 Rotational atherectomy 4(1.1%) 6(1.7%) 0.535 4(1.6%) 4(1.6%) 1.000 Aspiration of thrombus 2(0.5%) 3(0.9%) 0.678 1(0.4%) 1(0.4%) 1.000 IVUS 4(1.1%) 6(1.7%) 0.535 3(1.2%) 1(0.4%) 0.624 Medication Aspirin 368(98.7%) 345(98.3%)) 0.767 253(98.8%) 252(98.4%) 0.725 Statin 325(87.1%) 300(85.5%) 0.519 200(78.1%) 203(79.3%) 0.829 Beta blockers 289(77.5%) 277(78.9%) 0.654 220(85.9%) 221(86.3%) 1.000 CABG=coronary artery bypass graft ; DES=drug-eluting stent; DM= diabetes mellitus; EPD=embolic protection devices; IVUS= intravascular ultrasound; NCA= native coronary artery; PCI=percutaneous coronary intervention; PTCA= percutaneous coronary angioplasty. Table 3 Procedure-related complications of patients with prior CABG (n=724). Outcomes Unmatched Matched No DM DM P value No DM DM P value n=373 n=351 n=256 n=256 In-hospital mortality 0(0.0%) 2(0.6%) 0.235 0(0.0%) 1(0.4%) 1.000 Procedural complications Dysrhythmia 1(0.3%) 2(0.6%) 0.613 1(0.4%) 1(0.4%) 1.000 Angina in 24h 13(3.5%) 22(6.3%) 0.086 6(2.3%) 13(5.1%) 0.159 Periprocedural MI 4(1.1%) 5(1.4%) 0.746 2(0.8%) 3(1.2%) 1.000 AHF 1(0.3%) 3(0.9%) 0.359 1(0.4%) 1(0.4%) 1.000 Stroke 1(0.3%) 2(0.6%) 0.613 0(0.0%) 2(0.8%) 0.499 Dissection 1(0.3%) 2(0.6%) 0.613 1(0.4%) 1(0.4%) 1.000 Acute closure 0(0.0%) 2(0.6%) 0.235 0(0.0%) 1(0.4%) 1.000 Bleeding 2(0.5%) 5(1.4%) 0.273 2(0.8%) 4(1.6%) 0.686 AHF=acute heart failure; CABG=coronary artery bypass graft ; DM= diabetes mellitus; MI= myocardial infarction; PCI=percutaneous coronary intervention. Table 4 Follow-up outcomes of patients with prior CABG (n=724) Outcomes Unmatched Matched No DM DM P value No DM DM P value n=373 n=351 n=256 n=256 MACEs 114(30.6%) 128(36.5%) 0.055 75(29.3%) 96(37.5%) 0.051 Cardiac death 18(4.8%) 18(5.1%) 0.695 15(5.9%) 14(5.5%) 0.871 MI 43(11.5%) 62(17.7%) 0.010 33(12.9%) 47(18.4%) 0.078 HF 39(10.5%) 48(13.7%) 0.095 22(8.6%) 33(12.9%) 0.117 Revascularization 66(17.7%) 66(18.8%) 0.593 47(18.4%) 50(19.5%) 0.747 CABG=coronary artery bypass graft; DM= diabetes mellitus; HF=acute heart failure; MACEs= major adverse cardiac events; MI= myocardial infarction. Supporting Information Figure Legends Figure S1 Incidence of MACEs ( A), cardiac death (B), MI(C), HF(D) or revascularization (E) of patients with PCI in only NCA ( No DM vs DM) using the Kaplan-Meier method. P value was calculated by log-rank test. DM= diabetes mellitus, HF=acute heart failure, NCA= native coronary artery, MACEs= major adverse cardiac events, MI= myocardial infarction. Figure S2 Incidence of MACEs ( A), cardiac death (B), MI(C), HF(D) or revascularization (E) of patients with PCI in NCA and graft ( No DM vs DM) using the Kaplan-Meier method. P value was calculated by log-rank test. DM= diabetes mellitus, HF=acute heart failure, NCA= native coronary artery, MACEs= major adverse cardiac events, MI= myocardial infarction. Figure S3 Incidence of MACEs ( A), cardiac death (B), MI(C), HF(D) or revascularization (E) of patients with first-generation DES PCI ( No DM vs DM) using the Kaplan-Meier method. P value was calculated by log-rank test. DM= diabetes mellitus, HF=acute heart failure, NCA= native coronary artery, MACEs= major adverse cardiac events, MI= myocardial infarction. Figure S4 Incidence of MACEs ( A), cardiac death (B), MI(C), HF(D) or revascularization (E) of patients with second-generation DES PCI ( No DM vs DM) using the Kaplan-Meier method. P value was calculated by log-rank test. DM= diabetes mellitus, HF=acute heart failure, NCA= native coronary artery, MACEs= major adverse cardiac events, MI= myocardial infarction. Supplementary Files SupplementalFigureS4.tif SupplementalFigureS3.tif SupplementalFigureS2.tif SupplementalFigureS1.tif FigS1.png FigS2.png SupplementalFigureS2.tif SupplementalFigureS4.tif SupplementalFigureS3.tif SupplementalFigureS1.tif SupplementalTablesubgroup.docx Cite Share Download PDF Status: Published Journal Publication published 06 Apr, 2020 Read the published version in BMC Cardiovascular Disorders → Version 3 posted Editorial decision: Accept 25 Mar, 2020 Review # 2 received at journal 11 Mar, 2020 Review # 1 received at journal 11 Mar, 2020 Reviewers invited by journal 01 Mar, 2020 Reviewer # 1 agreed at journal 01 Mar, 2020 Reviewer # 2 agreed at journal 01 Mar, 2020 Editor assigned by journal 16 Feb, 2020 Submission checks completed at journal 15 Feb, 2020 Editor invited by journal 15 Feb, 2020 You are reading this latest preprint version Show more versions Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. 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PCI= percutaneous coronary intervention, DESs= drug-eluting stents.","description":"","filename":"Figure11.png","url":"https://assets-eu.researchsquare.com/files/d64c0e86-72e0-4334-8a7b-38d93ee3558c/v3/Figure_1[1].png"},{"id":506753,"identity":"9710c7ae-cde6-4eb7-b0e5-03d4cd0f9154","added_by":"auto","created_at":"2020-02-18 14:03:11","extension":"png","order_by":2,"title":"Figure 2","display":"","copyAsset":false,"role":"figure","size":571336,"visible":true,"origin":"","legend":"Dotplot of absolute standardized differences before and after matching.","description":"","filename":"Figure21.png","url":"https://assets-eu.researchsquare.com/files/d64c0e86-72e0-4334-8a7b-38d93ee3558c/v3/Figure_2[1].png"},{"id":506755,"identity":"cb65d042-ff29-46dc-a69b-14af2802d0c2","added_by":"auto","created_at":"2020-02-18 14:03:12","extension":"png","order_by":3,"title":"Figure 3","display":"","copyAsset":false,"role":"figure","size":2784486,"visible":true,"origin":"","legend":"Incidence of MACEs ( A), cardiac death (B), MI(C), HF(D) or revascularization (E) in the No DM group (blue line) compared with the DM group (red line) using the Kaplan-Meier method. P value was calculated by log-rank test. DM= diabetes mellitus, HF=acute heart failure, MACEs= major adverse cardiac events, MI= myocardial infarction.","description":"","filename":"Figure31.png","url":"https://assets-eu.researchsquare.com/files/d64c0e86-72e0-4334-8a7b-38d93ee3558c/v3/Figure_3[1].png"},{"id":506757,"identity":"99460f29-3ea1-46f4-9a7f-c496120d3ea1","added_by":"auto","created_at":"2020-02-18 14:03:13","extension":"png","order_by":4,"title":"Figure 4","display":"","copyAsset":false,"role":"figure","size":534495,"visible":true,"origin":"","legend":"Univariable and multivariable analyses of factors associated with major adverse cardiac events (MACEs) are performed with Cox proportional hazards regression, HRs with 95% CIs are shown. 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14:03:10","extension":"docx","order_by":0,"title":"","display":"","copyAsset":false,"role":"supplement","size":70355,"visible":true,"origin":"","legend":"","description":"","filename":"SupplementalTablesubgroup.docx","url":"https://assets-eu.researchsquare.com/files/d64c0e86-72e0-4334-8a7b-38d93ee3558c/v3/Supplemental Table - subgroup .docx"}],"financialInterests":"","formattedTitle":"Percutaneous Coronary Intervention in Diabetic versus Non-diabetic Patients with Prior Coronary Artery Bypass Grafting: A Propensity Score Matching Study","fulltext":[{"header":"Background","content":"\u003cp\u003eDiabetic patients have a higher prevalence of coronary artery disease (CAD) than the general population, manifesting as diffuse lesions and severe atherosclerosis in the left main artery and multiple other vessels \u003csup\u003e[1]\u003c/sup\u003e, severe symptoms often developing earlier in life combined with a substantially poorer prognosis than non-diabetic patients \u003csup\u003e[2,3]\u003c/sup\u003e. It has been reported that diabetes is considered a predictor of adverse events such as myocardial infarction (MI), repeat revascularization and cardiac death for patients who have undergone coronary artery bypass grafting (CABG) \u003csup\u003e[4\u0026ndash;6]\u003c/sup\u003e.\u003c/p\u003e\n\u003cp\u003eFor patients with prior CABG who require repeat revascularization, percutaneous coronary intervention (PCI) is usually the preferred strategy, rather than redo CABG, because of the low procedural mortality and similar long-term outcome \u003csup\u003e[7-8]\u003c/sup\u003e, combined with placement o f a drug-eluting stent (DES)\u003csup\u003e[9]\u003c/sup\u003e. Despite a number of studies investigating the impact that diabetes has on the clinical outcome of PCI with DES in patients without prior CABG \u003csup\u003e[10-11]\u003c/sup\u003e, little is known about the influence of diabetes on outcomes of PCI with DES in patients who have previously undergone CABG.\u003c/p\u003e\n\u003cp\u003eIn this study, we retrospectively assessed the clinical data of non-diabetic and diabetic patients with prior CABG who had subsequently received PCI with DES, aiming to establish the impact of DM on the long-term outcomes of PCI for restenosis after CABG.\u003c/p\u003e"},{"header":"Methods","content":"\u003cp\u003e\u003cstrong\u003eStudy design: \u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eThis study was a retrospective observational study conducted in Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart Lung and Blood Vessel Diseases, Beijing, China. A total of 724 patients with prior CABG were selected from the institution's PCI registry (2009 to 2017) who had undergone PCI with DES in a native coronary artery (NCA), following CABG surgery for coronary atherosclerotic heart disease in the same hospital. Patients were segregated into a diabetes mellitus (DM) or non-diabetes mellitus (No DM) group, according to whether or not they suffered from DM. All data were reviewed by one cardiac surgeon and two cardiologists, the latter contacting patients for follow-up outcomes by telephone, mail or visit. The study was approved by the Institutional Ethics Committee of Beijing Anzhen Hospital.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u0026nbsp;\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eDefinitions used in this study\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003ePatients\u0026rsquo; data before PCI was defined as baseline data. DM was defined as either a previous diagnosis of DM treated with diet, oral agents, peptide analogs or insulin, or a new diagnosis after index hospitalization \u003csup\u003e[12]\u003c/sup\u003e before PCI. A graft with a stenosis of \u0026gt;70% of its diameter was defined as stenosis. A graft with stenosis or occlusion was classified as a diseased graft in this study. The classification of ischemic territory was based on the results of coronary angiography (CAG) after re-hospitalization and also referred to the results prior to CABG. NCA related to ischemic territory was defined as relevant NCA. Paclitaxel-eluting and sirolimus-eluting stents were defined as first-generation DES. Everolimus-eluting and zotarolimus-eluting stents were defined as second-generation DES. Procedural complications refer to complications post PCI. PCI failure was defined as failure to implant a stent at one lesion site.\u003c/p\u003e\n\u003cp\u003eThe primary end-point was a major adverse cardiac event (MACE), defined as the combined incidence of either cardiac death, myocardial infarction (MI), heart failure (HF) or revascularization, as independently adjudicated by an events committee. Cardiac death was defined as any death due to MI, HF, lethal arrhythmia or sudden death in a previously stable patient \u003csup\u003e[13]\u003c/sup\u003e. MI was defined as: (1) elevation of\u0026nbsp;myocardial enzymes such as cardiac troponin T (cTnT) or creatine kinase-muscle/brain (CK-MB) \u0026gt;2 fold higher than the upper normal value and (2) changes in ST-segment and T-wave (ST-T) on electrocardiography \u003csup\u003e[14]\u003c/sup\u003e. HF was defined as hospitalization for progressive heart failure with clinical and radiographic signs. Revascularization was defined as undergoing a subsequent revascularization procedure by PCI or Redo CABG after discharge from the Department of Cardiology, Anzhen Hospital.\u003c/p\u003e\n\u003cp\u003e\u0026nbsp;\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eStatistical analysis\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eAll results were analyzed using Stata SE for Windows, version 15.0 (Stata\u0026nbsp;Corporation, College Station, TX, USA) statistical package and IBM SPSS Statistics for Windows, version 22.0. Categorical variables are presented as raw numbers (%) and continuous variables as means \u0026plusmn; standard deviation. Comparisons of the DM and No DM groups were accomplished using a Fisher\u0026rsquo;s exact test for each variable and Mann-Whitney-Wilcox nonparametric test for continuous variables. To reduce the impact of potential confounding on MACEs on the results of the observational study, 1:1 propensity score matching was conducted to choose patients with comparable baseline data. After evaluation of covariates associated clinically and / or statistically with the treatment group and removal of repeatedly defined or collinear variables, including baseline characteristics, risk factors, medical history, clinical conditions at admission and treatment during hospitalization, 36 variables listed in Figure 2 were included in the propensity score matching model using greedy nearest neighbor matching without replacement and a caliper of 0.02. The absolute standardized difference in variables included for the calculation of propensity score were compared before and after propensity-score matching. The absolute standardized difference cut-off point for the variables included in the calculation was fixed at 10.0%. After matching, Cox proportional hazards regression analysis was also conducted to assess the association between variables and follow-up outcomes. Univariable Cox proportional hazards regression models were initially conducted, followed by multivariable Cox proportional hazards regression models.\u0026nbsp; The candidate variables were potential confounding variables that were either mostly included in the propensity score matching model or reported more than once with an effect on cardiac death or MACEs. After forward stepwise selection with inclusion criteria both set at P=0.2, the variables were eventually included in multivariable Cox proportional hazards regression models of cardiac death and MACEs, respectively. Outcomes were compared using a log-rank test and presented as Kaplan-Meier curves. For all analyses reported, P values were 2-sided. Statistical differences were considered significant for values of P ＜0.05.\u003c/p\u003e"},{"header":"Results","content":"\u003cp\u003e\u003cstrong\u003eBaseline characteristics\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eIn this study, 724 patients were included of which 351 patients (48.5%) exhibited DM. In the DM group, 43.3% of patients presented between 1 and 5 years after CABG and 33.0% between 5 and 10 years, as shown in Figure 1. The absolute standardized difference values before and after matching are shown in Figure 2. Following the matching, absolute standardized differences \u0026lt; 10.0% for those variables included indicated a relatively small imbalance.\u003c/p\u003e\n\u003cp\u003eThe baseline characteristics are shown in Table 1. After matching, there were 256 patients in each group, and the statistical difference in age (years), BMI, duration of period after CABG, numbers of patients that were ＞65 years old, had chronic lung disease, prior cerebrovascular accidents (CVA) or prior PCI were not as significant as they had been before matching the two groups. The characteristics of the CAGs of the diseased grafts and relevant NCAs are also shown in Table 1, with no significant difference between the two groups before matching. The relevant indicators of blood sugar of patients such as glucose concentratrion and glycosylated hemoglobin (HbA1c) are also shown in Table 1.\u003c/p\u003e\n\u003cp\u003e\u0026nbsp;\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003ePCI-related baseline characteristics\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eTable 2 displays the procedural baseline characteristics, which are also included in the propensity score matching. After matching, PCI was mostly performed in NCA only (No DM: 87.1% vs DM: 87.9%) with first-generation DES used widely (No DM: 62.1% vs DM: 64.8%) in each group. A small proportion of patients also underwent percutaneous coronary angioplasty (PTCA) in addition to stent implantation (No DM: 7.4% vs DM: 9.0%) and PCI failure in stent implantation in one lesion site (No DM: 4.3% vs DM: 5.1%). EPD, rotational atherectomy, aspiration of thrombus or intravascular ultrasound (IVUS) were not greatly used in either group.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u0026nbsp;\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eProcedural complications\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eTable 3 describes recorded procedural complications. After matching, the DM group exhibited slightly high in-hospital mortality, with a higher incidence of angina after 24h (5.1%), periprocedural MI (1.2%), stroke (0.8%) and bleeding (1.6%), but there was no significant difference between the two groups.\u003c/p\u003e\n\u003cp\u003e\u0026nbsp;\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eFollow-up outcomes\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eComplete follow-up data were obtained in the overall study population, as displayed in Table 4 and Figure 3. The median follow-up duration was 5.13 years. After matching, Kaplan-Meier curves (Figure 4 A) indicated that the cumulative overall rate of MACEs was higher in the DM group at 2 years (No DM: 15.3% vs DM: 19.8%), 5 years (No DM: 30.9% vs DM: 37.8%) and at 8 years (No DM: 38.5% vs DM: 52.2%) (hazard ratio [HR]: 1.35; 95% confidence interval [CI]: 1.00 to 1.83 for DM vs No DM; P=0.052), with an apparent increase in the difference between the two groups over time. The curves indicated that two-, 5- and 8-year incidence of cardiac death in each group (Figure 4 B) were similar (No DM: 1.6%, 5.8%, 10.5% vs DM 1.2%, 5.8%, 9.3%; HR: 0.94; 95% CI: 0.45 to 1.95 for DM vs No DM; P=0.871). There was also no statistical difference in incidence of MI (HR: 1.49; 95% CI: 0.95 to 2.32 for DM vs No DM; P=0.080), HF (HR: 1.54; 95% CI: 0.90 to 2.63 for DM vs No DM; P=0.120) or repeated revascularization (HR: 1.07; 95% CI: 0.72 to 1.59 for DM vs No DM; P=0.747) between the two groups, although there was a trend that the incidence of MI or HF in the DM group increased over time.\u003c/p\u003e\n\u003cp\u003eMultivariable Cox proportional hazards regression (Figure 4) demonstrated that patients with hypertension (adjusted HR: 1.85; 95% CI: 1.32 to 2.59; P＜0.001), aspiration of thrombus during PCI (adjusted HR: 3.37; 95% CI: 1.05 to 10.84; P=0.041), prior HF (adjusted HR: 4.30; 95% CI: 1.82 to 10.14; P=0.001) or LVEF＜50% (adjusted HR: 1.52; 95% CI: 1.07 to 2.17; P=0.020) were more likely to suffer a MACE. Additionally, use of a statin provided protection from MACEs (adjusted HR: 0.57; 95% CI: 0.41 to 0.78; P=0.001).\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u0026nbsp;\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eSubgroup analysis of PCI \u003c/strong\u003e\u003cstrong\u003ein different target vessels\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eTo reduce the influence of PCI in different target vessels, we performed two additional subgroup analyses of patients that had undergone PCI only in the NCA or PCI in both the NCA and graft. The baseline characteristics of the two subgroups are detailed within Additional File 1: Tables S1, S2 and S3. The follow-up outcomes of the two subgroups are provided separately in Tables S4, S5 and Figures S1, S2.\u003c/p\u003e\n\u003cp\u003eThe follow-up outcomes of patients that underwent PCI in only the NCA were consistent with all clinical endpoints experienced by the whole population. Compared with the non-diabetic patients who had previously undergone CABG, subsequent PCI in only the NCA in diabetic patients appeared to result in similar outcomes (Table S4, Figure S1), including MACEs (adjusted HR: 1.13; 95% CI: 0.85 to 1.49 for DM vs No DM; P=0.325), cardiac death (adjusted HR: 0.85; 95% CI: 0.41 to 1.78 for DM vs No DM; P=0.781), MI (adjusted HR: 1.32; 95% CI: 0.84 to 2.01 for DM vs No DM; P=0.069), HF (adjusted HR: 1.41; 95% CI: 0.87 to 2.27 for DM vs No DM; P=0.211) or repeated revascularization (adjusted HR: 0.93; 95% CI: 0.64 to 1.37 for DM vs No DM; P=0.836).\u003c/p\u003e\n\u003cp\u003eWhen it came to the follow-up outcomes of patients with PCI in both the NCA and graft (Table S5, Figure S2), diabetic patients with subsequent PCI in both the NCA and graft were more likely to experience MACEs (adjusted HR: 4.00; 95% CI: 1.67 to 9.58 for DM vs No DM; P=0.003), cardiac death (adjusted HR: 16.04; 95% CI: 1.58 to 162.50 for DM vs No DM; P=0.066), MI (adjusted HR: 3.78; 95% CI: 1.29 to 11.06 for DM vs No DM; P=0.010), HF (adjusted HR: 7.61; 95% CI: 1.06 to 54.57 for DM vs No DM; P=0.091) or repeated revascularization (adjusted HR: 3.36; 95% CI: 1.05 to 10.68 for DM vs No DM; P=0.276).\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u0026nbsp;\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eSubgroup analysis of PCI with different generation DESs \u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eTo reduce the influence of PCI with different generation DESs, we performed two additional subgroup analyses of patients that had undergone PCI with first-generation DESs or second-generation DESs. The baseline characteristics of the two subgroups are detailed within Additional File 1: Tables S6, S7 and S8. The follow-up outcomes of the two subgroups are provided separately in Tables S9, S10 and Figures S3, S4.\u003c/p\u003e\n\u003cp\u003eThe follow-up outcomes of patients that underwent PCI with first-generation DESs were consistent with all clinical endpoints experienced by the whole population. Compared with the non-diabetic patients who had previously undergone CABG, subsequent PCI with first-generation DESs in diabetic patients appeared to result in similar outcomes (Table S9, Figure S3).\u003c/p\u003e\n\u003cp\u003eWhen it came to the follow-up outcomes of patients with PCI with second-generation DESs (Table S10, Figure S4), diabetic patients with subsequent PCI with second-generation DESs were more likely to experience MACEs (adjusted HR: 1.76; 95% CI: 1.00 to 3.08 for DM vs No DM; P=0.016), MI (adjusted HR: 1.90; 95% CI: 0.75 to 4.81 for DM vs No DM; P=0.038) and HF (adjusted HR: 1.87; 95% CI: 0.72 to 4.89 for DM vs No DM; P=0.018). The outcomes of cardiac death (adjusted HR: 1.10; 95% CI: 0.01 to 1.47 for DM vs No DM; P=0.852) and repeated revascularization (adjusted HR: 1.67; 95% CI: 0.79 to 3.53 for DM vs No DM; P=0.305) are similar between two groups.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u0026nbsp;\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eFollow-up outcomes of patients with incomplete revascularization vs complete revascularization\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eWe reviewed the coronary angiography files, 37 patients (5.1%) received incomplete revascularization (IR) by PCI and 687 patients (94.9%) received complete revascularization (CR) by PCI after CABG. Follow-up outcomes of patients with IR vs CR are shown in Table S11. Compared with patients with CR, patients with IR are more likely to have MACEs (40.5% vs 33.0%), cardiac death (8.1% vs 4.8%) and MI (21.6% vs 14.1%), though there are no significant differences between two groups.\u003c/p\u003e"},{"header":"Discussion","content":"\u003cp\u003eWe performed a retrospective observational study to explore the outcomes of PCI with DES in diabetic vs non-diabetic patients who had previously undergone CABG in our single-center registry. We found that, compared to non-diabetic patients with prior CABG, subsequent PCI within the NCA with DES in diabetic patients appeared to result in a similar overall incidence of MACEs, cardiac death, MI, HF or repeated revascularization, extending our current understanding of the safety and efficacy of DES even in high-risk patients with prior CABG. This suggests that a DES may be considered the default option in these patient\u0026nbsp;populations. In this study we also found that hypertension, prior HF, LVEF＜50% and aspiration of thrombus are predictive of overall MACEs and patients taking statins are less likely to experience MACEs. Our results were based on matching propensity scores, which suggests that our findings are not due to negative confounding.\u003c/p\u003e\n\u003cp\u003eDiabetic patients with CAD are reported to have dysfunctional endothelial cells, increased atherosclerotic burden and fragile lipid-rich plaques \u003csup\u003e[15,16]\u003c/sup\u003e, microcirculation disorder involving smaller vessels, and prothrombotic and proinflammatory states \u003csup\u003e[17-18]\u003c/sup\u003e, which are related to progression of NCA disease. It is confirmed that CAD in diabetic patients appears as diffuse atherosclerosis with chronic total occlusion (CTO), opening and bifurcation lesions or multivessel disease and left main disease\u003csup\u003e[19]\u003c/sup\u003e, leading to fewer amenable options for re-intervention and suboptimal stent expansion \u003csup\u003e[20]\u003c/sup\u003e. In this study, although the characteristics of the lesions in the NCAs relevant to ischemic territory are similar in both diabetic and non-diabetic patients, those in each group represent a high proportion of the CTO lesions, openings involving lesions, branches involving lesions or diffuse lesions. We consider that this is due to the combined CAD risk factors, such as hypertension, dyslipidemia, diabetes mellitus, fat, smoking and gender. In order to remove the influence of confounding CAD risk factors and to compare between the DM group and No DM group more precisely, we used the propensity score matching method, described in detail in the statistical analysis section.\u003c/p\u003e\n\u003cp\u003eAtherosclerosis is also reported to play an important role in later graft failure (graft age ＞6 months) \u003csup\u003e[20]\u003c/sup\u003e. Graft atherosclerosis in diabetic patients has a larger necrotic core with unstable plaques \u003csup\u003e[21]\u003c/sup\u003e, which is friable and more prone to distal coronary embolization \u003csup\u003e[2]\u003c/sup\u003e. Compared with non-diabetic patients with prior CABG, diabetic patients have a higher rate of graft stenosis and recurrent myocardial ischemic events \u003csup\u003e[22, 23]\u003c/sup\u003e, due to the progression of NCA disease or graft failure \u003csup\u003e[2]\u003c/sup\u003e. In this study the majority of patients in each group had diseased grafts (81.2% and 79.2% in the No DM and DM groups, respectively), and a small proportion of the remaining patients in each group had myocardial ischema caused by isolated NCA lesions as a consequence of the progression of NCA disease (18.8% and 20.8% in the No DM and DM groups, respectively).\u003c/p\u003e\n\u003cp\u003eDES are superior to bare metal stents (BMS), in terms of their strut thickness and polymer coating composition, reducing repeat revascularization and in-stent thrombosis in addition to MI in non-diabetic patients \u003csup\u003e[19]\u003c/sup\u003e. Published literature indicates that PCI with DES in diabetic patients compared with non-diabetic patients results in significantly higher mortality, reinfarction, and repeat revascularization for in-stent restenosis \u003csup\u003e[24-26]\u003c/sup\u003e. The pathological mechanism of in-stent restenosis in diabetic patients is associated with excessive endothelial hyperplasia, vascular remodeling or increased platelet aggregation \u003csup\u003e[27]\u003c/sup\u003e. However, in this study we found different results, especially when performing additional subgroup analysis of patients with PCI in only the NCA, in that PCI in the NCA with DES in diabetic patients compared with non-diabetic patients did not result in a high incidence of cardiac death, HF or repeat revascularization, and the incidence of MI between the two groups was not significantly different. However, one key observation should be clearly noted, that patients in that study included those without prior CABG. Conversely, all patients included in this study underwent prior CABG in our cardiac center, which could be considered a pretreatment for diabetic patients and functions as protection. In addition, all were high risk patients, especially in the DM group. They were older with a greater number of comorbidities and had severe NCA or graft lesions.\u003c/p\u003e\n\u003cp\u003eThe studies of Ahmed \u003csup\u003e[28]\u003c/sup\u003e and Ashfaq \u003csup\u003e[\u003c/sup\u003e\u003csup\u003e29]\u003c/sup\u003e reported the influence of DM on outcomes in saphenous vein graft (SVG) stenting, with similar conclusions, that PCI with DES in diabetics resulted in long-term overall rates of MACEs, death, MI and repeat revascularization that were worse than in non-diabetics, quite different from Pendyala\u0026rsquo;s conclusion that diabetic patients undergoing SVG PCI had similar long-term outcomes \u003csup\u003e[27]\u003c/sup\u003e. In the present study, after analysis of the whole study population (after matching, n=512), we found that the overall incidence of MACEs (DM: 37.5% vs No DM: 29.3%), principally driven by MI (DM: 18.4% vs No DM: 12.9%), were not statistically different between the two groups despite an increasing trend over time. Considering the conflicting data of all the patients that received PCI in the NCA and that a minority of patients were treated with PCI in both graft and NCA (No DM: 12.9% vs DM: 12.1), we performed further subgroup analysis of patients with PCI in only the NCA (n=635). We found that, compared to non-diabetic patients with prior CABG, subsequent DES in only the NCA of diabetic patients appeared to result in similar outcomes, such as rates of MACEs, cardiac death, MI, HF and repeat revascularization. Additional subgroup analysis of patients with PCI in both the NCA and graft, despite the small sample size of patients in this subgroup (n=89), demonstrated that, compared to non-diabetic patients with prior CABG, subsequent DES in the NCA and grafts of diabetic patients resulted in worse outcomes, consistent with Ahmed and Ashfaq\u0026rsquo;s studies. According to the 2018 ESC/EACTS Guidelines for myocardial revascularization \u003csup\u003e[2]\u003c/sup\u003e, it is recommended that PCI in the NCA should be considered rather than PCI in an SVG graft, because that is associated with a high risk of periprocedural MI \u003csup\u003e[30]\u003c/sup\u003e and worse long-term outcomes such as all-cause death, MI or revascularization \u003csup\u003e[31]\u003c/sup\u003e for no-reflow, subsequent in-stent restenosis, distant target lesions and excessive tortuosity \u003csup\u003e[8]\u003c/sup\u003e, especially for PCI in an SVG of a diabetic patient for graft atherosclerosis with a larger necrotic core and friable plaques \u003csup\u003e[21]\u003c/sup\u003e.\u0026nbsp;\u003c/p\u003e\n\u003cp\u003eIn this study, we also provided follow-up outcomes of patients with IR vs CR by PCI. Achieving\u0026nbsp;CR\u0026nbsp;of all significantly obstructed coronary artery has been an established goal of PCI, and more recent data demonstrate a salutary effect of\u0026nbsp;CR\u0026nbsp;following PCI on long-term outcomes. IR\u0026nbsp;is associated with increased mortality following PCI, as well as with an increased incidence of MI, repeat\u0026nbsp;revascularization, and MACCEs \u003csup\u003e[32]\u003c/sup\u003e. Though, in our study the sample size of patients with IR was too small (5.1%), which would influence statistical results,, we still believed that it made a little sense, compared with patients with CR, patients with IR were more likely to have MACEs (40.5%), cardiac death (8.1%) and MI (21.6%), though there were no significant difference between two groups. Further randomized controlled trial study with a larger sample size and longer follow-up may be required for patient with prior CABG.\u003c/p\u003e\n\u003cp\u003e\u0026nbsp;\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eLimitations\u003c/strong\u003e\u0026nbsp;\u003c/p\u003e\n\u003cp\u003eFirstly, this was a retrospective observational single-center study and so is subject to all the limitations of observational single-center studies, such as patient selection and a single therapeutic method, which might affect the results. Secondly, the angiography film results were analyzed by one cardiac surgeon and one cardiologist. Thirdly, the classification of graft lesions was in reference to the evaluation criteria of native vessels. Fourthly, the decision to perform PCI for each patient was taken by 2 operators, mostly based on an evaluation of the CAG results. Fifthly, 6 non-DM patients who had diabetes during the follow-up period were excluded from this study. Sixthly, we didn\u0026rsquo;t do PS matching for sub-group analysis. Despite these limitations, the results were derived from the largest angiographic study in patients with prior CABG so far published. In addition, the statistical analyses utilized rigorous methodology.\u003c/p\u003e"},{"header":"Conclusions","content":"\u003cp\u003eCompared to non-diabetic patients with prior CABG, subsequent PCI in an NCA with DES in diabetic patients appears to result in a similar incidence of overall MACEs, cardiac death, MI, HF and repeated revascularization, suggesting that DES may be considered the default option for these patient\u0026nbsp;populations. We also found that hypertension, prior HF, LVEF＜50% and aspiration of thrombus are predictive for overall rate of MACE in diabetic patients with prior CABG. Patients that were administered statins were less likely to experience MACEs.\u003c/p\u003e"},{"header":"List Of Abbreviations","content":"\u003cp\u003eAHF: acute heart failure; AMI: acute myocardial infarction; BMI: body mass index; CABG: coronary artery bypass graft; CTO: chronic total occlusion; CVA: cerebrovascular accident; DES: drug-eluting stent ; DM: diabetes mellitus; HbA1c: glycosylated hemoglobin; HF: heart failure; LVEF: left ventricular ejection fraction; NCA: native coronary artery; MACEs: major adverse cardiac events; PCI: percutaneous coronary intervention; PVD: peripheral vascular disease; SA: stable angina; SVG: saphenous vein graft ; UA: unstable angina.\u003c/p\u003e"},{"header":"Declarations","content":"\u003cp\u003e\u003cstrong\u003eEthics approval and consent to participate\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eNot applicable.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eConsent for publication \u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eNot applicable.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eAvailability of data and materials\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eThe datasets generated and analyzed for this current study are available from the corresponding author upon reasonable request.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eCompeting interests\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eAll authors declare that they have no competing interests.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eFunding \u003c/strong\u003eThis study was supported by grants from the National Natural Science Foundation of China (81370294, 81570291, 81770320). Professor Jiangang Wang owned the funding, a member of designers of this study.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eAuthors' contributions\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eThe most important acknowledgment is to the participants in the study at Anzhen Hospital. JG W obtained funding. JG W, XL M, and R D designed the study. PF C, YC Z, CW Z, M X and Q Y collected and analyzed the data. XL M drafted the manuscript. All authors have read and approved the manuscript.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eAcknowledgements\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eNot applicable\u003c/p\u003e"},{"header":"References","content":"\u003cp\u003e[1] O\u0026rsquo;Donoghue ML, Vaidya A, Afsal R, et al. An invasive or conservative strategy in patients with diabetes mellitus and non-ST-segment elevation acute coronary syndromes: A collaborative meta-analysis of randomized trials. 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Predictors of revascularization method and long-term outcome of percutaneous coronary intervention or repeat coronary bypass surgery in patients with multivessel coronary disease and previous coronary bypass surgery. Eur Heart J 2006;27:413\u0026ndash;418.\u003c/p\u003e\n\u003cp\u003e[8] Scarsini R, Zivelonghi C, Pesarini G, et al. Repeat revascularization: Percutaneous coronary intervention after coronary artery bypass graft surgery. Cardiovasc Revasc Med 2016;17(4):272-278.\u003c/p\u003e\n\u003cp\u003e[9] Boyden TF, Nallamothu BK, Moscucci M, et al. Meta-analysis of randomized trials of drug-eluting stents versus bare metal stents in patients with diabetes mellitus. Am J Cardiol. 2007;99:1399\u0026ndash;402.\u003c/p\u003e\n\u003cp\u003e[10] Mulukutla SR, Vlachos HA, Marroquin OC, et al. Impact of drug‐eluting stents among insulin-treated diabetic patients: A report from the National Heart, Lung, and Blood Institute Dynamic Registry. 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Circulation 2002;106:3037-43.\u0026nbsp;\u003c/p\u003e\n\u003cp\u003e[18] Haffner SM, Lehto S, R\u0026ouml;nnemaa T, et al. Mortality from coronary heart disease in subjects with type 2 diabetes and in nondiabetic subjects with and without prior myocardial infarction. N Engl J Med 1998;339:229-34.\u0026nbsp;\u003c/p\u003e\n\u003cp\u003e[19] Guandalini GS, Bangalore S. The Potential Effects of New Stent Platforms for Coronary Revascularization in Patients with Diabetes. Can J Cardiol 2018;34(5):653-664.\u003c/p\u003e\n\u003cp\u003e[20] Scarsini R, Zivelonghi C, Pesarini G, et al. Repeat revascularization: Percutaneous coronary intervention after coronary artery bypass graft surgery. Cardiovasc Revasc Med 2016 ;17(4):272-8.\u003c/p\u003e\n\u003cp\u003e[21] Baars T, Konorza T, Kahlert P, et al. Coronary aspirate TNF \u0026alpha; reflects saphenous vein bypass graft restenosis risk in diabetic patients. Cardiovasc Diabetol 2013;12:12.\u003c/p\u003e\n\u003cp\u003e[22] Detre KM, Lombardero MS, Brooks MM, et al. The effect of previous coronary-artery bypass surgery on the prognosis of patients with diabetes who have acute myocardial infarction. Bypass Angioplasty Revascularization Investigation Investigators. N Engl J Med 2000;342(14):989-97.\u003c/p\u003e\n\u003cp\u003e[23] The BARI Investigators. Influence of diabetes on 5-year mortality and morbidity in a randomized trial comparing CABG and PTCA in patients with multivessel disease: The Bypass Angioplasty Revascularization Investigation (BARI).Circulation 1997;96:1761\u0026ndash;1769.\u003c/p\u003e\n\u003cp\u003e[24] Tailakh MA, Friger M, Zahger D, et al. Prospective study of the impact of diabetes mellitus newly diagnosed by glycated hemoglobin on outcomes in patients undergoing percutaneous coronary intervention. Eur J Intern Med 2017;37:69-74.\u003c/p\u003e\n\u003cp\u003e[25] De Luca G, Dirksen MT, Spaulding C, et al. Impact of diabetes on long-term outcome after primary angioplasty: insights from the DESERT cooperation. Diabetes Care 2013;36(4):1020-5..\u003c/p\u003e\n\u003cp\u003e[26] Wang H, Gao Z, Song Y, et al. Impact of Diabetes Mellitus on Percutaneous Coronary Intervention in Chinese Patients: A Large Single-Center Data. Angiology 2018;69(6):540-547.\u003c/p\u003e\n\u003cp\u003e[27] Pendyala LK, Loh JP, Kitabata H, et al. The impact of diabetes mellitus on long-term clinical outcomes after percutaneous coronary saphenous vein graft interventions in the drug-eluting stent era. J Interv Cardiol 2014;27(4):391-8.\u0026nbsp;\u003c/p\u003e\n\u003cp\u003e[28] Ahmed JM, Hong MK, Mehran R, et al. Influence of diabetes mellitus on early and late clinical outcomes in saphenous vein graft stenting. J Am Coll Cardiol 2000; 36(4):1186-93\u003c/p\u003e\n\u003cp\u003e[29] Ashfaq S, Ghazzal Z, Douglas JS, et al. Impact of diabetes on five-year outcomes after vein graft interventions performed prior to the drug-eluting stent era. J Invasive Cardiol 2006;18(3):100-5.\u003c/p\u003e\n\u003cp\u003e[30] Coolong A, Baim DS, Kuntz RE, et al. Saphenous vein graft stenting and major adverse cardiac events: A predictive model derived from a pooled analysis of 3958 patients. Circulation 2008;117:790\u0026ndash;797.\u003c/p\u003e\n\u003cp\u003e[31] Brilakis E S , O'Donnell C I , Penny W , et al. Percutaneous Coronary Intervention in\u0026nbsp;Native Coronary Arteries Versus Bypass\u0026nbsp;Grafts in Patients With Prior Coronary Artery Bypass Graft Surgery: Insights From the Veterans Affairs Clinical Assessment, Reporting, and Tracking Program. JACC Cardiovasc Interv 2016, 9(9):884-893.\u003c/p\u003e\n\u003cp\u003e[32] Kereiakes DJ.Reassessing the importance of complete versus incomplete coronary revascularization.Rev Cardiovasc Med 2014,15(1):24-30.\u003c/p\u003e"},{"header":"Tables","content":"\u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cstrong\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eTable 1\u0026nbsp;\u003c/span\u003e\u003c/strong\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eComparison of baseline characteristics of\u0026nbsp;\u003c/span\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003enon-diabetic vs diabetic patients\u003c/span\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;with prior CABG (n=724).\u003c/span\u003e\u003c/p\u003e\n\u003ctable border=\"1\" cellpadding=\"0\" cellspacing=\"0\" style=\"margin-left:-30.05pt;border-collapse:collapse;border:none;\" width=\"699\"\u003e\n \u003ctbody\u003e\n \u003ctr\u003e\n \u003ctd rowspan=\"3\" style=\"width: 120.5pt;border-top: 1pt solid black;border-left: none;border-bottom: 1pt solid black;border-right: none;padding: 0in 5.4pt;height: 21.9pt;vertical-align: top;\" valign=\"top\" width=\"23%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:center;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;margin-top:12.0pt;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eVariable\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"3\" style=\"width: 196.65pt;border-top: 1pt solid black;border-left: none;border-bottom: 1pt solid black;border-right: none;padding: 0in 5.4pt;height: 21.9pt;vertical-align: top;\" valign=\"top\" width=\"37.42857142857143%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;text-indent:48.0pt;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eUnmatched\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd rowspan=\"3\" style=\"width: 11.8pt;border-top: 1pt solid black;border-left: none;border-bottom: 1pt solid black;border-right: none;padding: 0in 5.4pt;height: 21.9pt;vertical-align: top;\" valign=\"top\" width=\"2.2857142857142856%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;text-indent:1.0in;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"3\" style=\"width: 195.55pt;border-top: 1pt solid black;border-left: none;border-bottom: 1pt solid black;border-right: none;padding: 0in 5.4pt;height: 21.9pt;vertical-align: top;\" valign=\"top\" width=\"37.285714285714285%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;text-indent:1.0in;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eMatched\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 78pt;border: none;padding: 0in 5.4pt;height: 20pt;vertical-align: top;\" valign=\"top\" width=\"19.88527724665392%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eNo DM\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 71.05pt;border: none;padding: 0in 5.4pt;height: 20pt;vertical-align: top;\" valign=\"top\" width=\"18.164435946462714%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;text-indent:12.0pt;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eDM\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd rowspan=\"2\" style=\"width: 47.6pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid black;padding: 0in 5.4pt;height: 20pt;vertical-align: top;\" valign=\"top\" width=\"12.045889101338432%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;margin-top:12.0pt;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eP value\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75.05pt;border: none;padding: 0in 5.4pt;height: 20pt;vertical-align: top;\" valign=\"top\" width=\"19.120458891013385%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eNo DM\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border: none;padding: 0in 5.4pt;height: 20pt;vertical-align: top;\" valign=\"top\" width=\"18.164435946462714%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;text-indent:12.0pt;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eDM\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd rowspan=\"2\" style=\"width: 49.6pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid black;padding: 0in 5.4pt;height: 20pt;vertical-align: top;\" valign=\"top\" width=\"12.619502868068833%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;margin-top:12.0pt;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eP value\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 78pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid black;padding: 0in 5.4pt;height: 17.4pt;vertical-align: top;\" valign=\"top\" width=\"26.395939086294415%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;text-indent:12.0pt;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003en=373\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 71.05pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid black;padding: 0in 5.4pt;height: 17.4pt;vertical-align: top;\" valign=\"top\" width=\"24.111675126903553%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;text-indent:6.0pt;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003en=351\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75.05pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid black;padding: 0in 5.4pt;height: 17.4pt;vertical-align: top;\" valign=\"top\" width=\"25.380710659898476%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;text-indent:6.0pt;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003en=256\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid black;padding: 0in 5.4pt;height: 17.4pt;vertical-align: top;\" valign=\"top\" width=\"24.111675126903553%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;text-indent:6.0pt;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003en=256\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 120.5pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"23%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eDemographics\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 78pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"14.857142857142858%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 71.05pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"13.571428571428571%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 47.6pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"9%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11.8pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"2.2857142857142856%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75.05pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"13.571428571428571%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 49.6pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"9.428571428571429%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 120.5pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"23%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;text-indent:6.0pt;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eAge(year)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 78pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"14.857142857142858%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e61.52\u003c/span\u003e\u003cspan style=\"font-size:16px;font-family:SimSun;\"\u003e±\u003c/span\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e9.23\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 71.05pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"13.571428571428571%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e63.64\u003c/span\u003e\u003cspan style=\"font-size:16px;font-family:SimSun;\"\u003e±\u003c/span\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e8.15\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 47.6pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"9%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0.001\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11.8pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"2.2857142857142856%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75.05pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e62.25\u003c/span\u003e\u003cspan style=\"font-size:16px;font-family:SimSun;\"\u003e±\u003c/span\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e8.71\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"13.571428571428571%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e62.86\u003c/span\u003e\u003cspan style=\"font-size:16px;font-family:SimSun;\"\u003e±\u003c/span\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e8.13\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 49.6pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"9.428571428571429%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0.409\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 120.5pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"23%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;text-indent:12.0pt;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e≥65 years\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 78pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"14.857142857142858%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e146(39.1%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 71.05pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"13.571428571428571%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e165(47.0%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 47.6pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"9%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0.036\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11.8pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"2.2857142857142856%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75.05pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e101(39.5%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"13.571428571428571%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e108(42.2%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 49.6pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"9.428571428571429%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0.590\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 120.5pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"23%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;text-indent:6.0pt;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eSex(Male)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 78pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"14.857142857142858%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e290(77.7%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 71.05pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"13.571428571428571%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e261(74.4%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 47.6pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"9%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0.296\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11.8pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"2.2857142857142856%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75.05pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e192(75.0%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"13.571428571428571%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e197(77.0%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 49.6pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"9.428571428571429%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0.679\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 120.5pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"23%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eComorbidities\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 78pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"14.857142857142858%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 71.05pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"13.571428571428571%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 47.6pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"9%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11.8pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"2.2857142857142856%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75.05pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"13.571428571428571%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 49.6pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"9.428571428571429%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 120.5pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"23%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;text-indent:6.0pt;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eHypertension\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 78pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"14.857142857142858%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e263(70.5%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 71.05pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"13.571428571428571%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e268(76.4%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 47.6pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"9%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0.078\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11.8pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"2.2857142857142856%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75.05pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e188(73.4%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"13.571428571428571%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e192(75.0%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 49.6pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"9.428571428571429%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0.762\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 120.5pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"23%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;text-indent:6.0pt;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eDyslipidemia\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 78pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"14.857142857142858%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e167(44.8%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 71.05pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"13.571428571428571%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e182(51.9%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 47.6pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"9%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0.063\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11.8pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"2.2857142857142856%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75.05pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e131(51.2%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"13.571428571428571%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e127(49.6%))\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 49.6pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"9.428571428571429%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0.791\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 120.5pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"23%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;text-indent:6.0pt;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eChronic renal disease\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 78pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"14.857142857142858%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e12(3.2%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 71.05pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"13.571428571428571%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e16(4.6%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 47.6pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"9%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0.441\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11.8pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"2.2857142857142856%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75.05pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e10(3.9%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"13.571428571428571%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e6(2.3%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 49.6pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"9.428571428571429%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0.447\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 120.5pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"23%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;text-indent:6.0pt;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eChronic lung disease\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 78pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"14.857142857142858%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e20(5.4%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 71.05pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"13.571428571428571%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e8(2.3%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 47.6pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"9%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0.035\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11.8pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"2.2857142857142856%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75.05pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e10(3.9%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"13.571428571428571%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e8(3.1%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 49.6pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"9.428571428571429%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0.811\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 120.5pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"23%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;text-indent:6.0pt;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003ePrior PVD\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 78pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"14.857142857142858%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e43(11.5%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 71.05pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"13.571428571428571%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e34(9.7%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 47.6pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"9%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0.470\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11.8pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"2.2857142857142856%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75.05pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e24(9.4%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"13.571428571428571%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e27(10.5%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 49.6pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"9.428571428571429%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0.768\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 120.5pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"23%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;text-indent:6.0pt;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003ePrior CVA\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 78pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"14.857142857142858%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e49(13.1%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 71.05pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"13.571428571428571%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e66(18.8%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 47.6pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"9%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0.042\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11.8pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"2.2857142857142856%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75.05pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e40(15.6%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"13.571428571428571%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e37(14.5%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 49.6pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"9.428571428571429%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0.805\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 120.5pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"23%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;text-indent:6.0pt;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003ePrior MI\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 78pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"14.857142857142858%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e52(13.9%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 71.05pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"13.571428571428571%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e75(21.4%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 47.6pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"9%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0.011\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11.8pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"2.2857142857142856%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75.05pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e43(16.8%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"13.571428571428571%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e40(15.6%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 49.6pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"9.428571428571429%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0.811\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 120.5pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"23%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;text-indent:6.0pt;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003ePrior HF\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 78pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"14.857142857142858%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e6(1.6%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 71.05pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"13.571428571428571%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e2(0.6%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 47.6pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"9%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0.288\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11.8pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"2.2857142857142856%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75.05pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e3(1.2%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"13.571428571428571%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e2(0.8%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 49.6pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"9.428571428571429%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e1.000\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 120.5pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"23%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;text-indent:6.0pt;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003ePrior PCI\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 78pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"14.857142857142858%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e14(3.8%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 71.05pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"13.571428571428571%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e26(7.4%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 47.6pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"9%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0.035\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11.8pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"2.2857142857142856%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75.05pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e13(5.1%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"13.571428571428571%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e14(5.5%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 49.6pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"9.428571428571429%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e1.000\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 120.5pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"23%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eSmoking\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 78pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"14.857142857142858%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e238(63.8%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 71.05pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"13.571428571428571%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e212(60.4%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 47.6pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"9%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0.358\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11.8pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"2.2857142857142856%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75.05pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e162(63.3%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"13.571428571428571%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e167(65.2%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 49.6pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"9.428571428571429%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0.712\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 120.5pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"23%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eBMI\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 78pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"14.857142857142858%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e25.70\u003c/span\u003e\u003cspan style=\"font-size:16px;font-family:SimSun;\"\u003e±\u003c/span\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e3.00\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 71.05pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"13.571428571428571%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e26.19\u003c/span\u003e\u003cspan style=\"font-size:16px;font-family:SimSun;\"\u003e±\u003c/span\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e3.18\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 47.6pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"9%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0.037\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11.8pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"2.2857142857142856%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New 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style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e25.96\u003c/span\u003e\u003cspan style=\"font-size:16px;font-family:SimSun;\"\u003e±\u003c/span\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e3.23\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 49.6pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"9.428571428571429%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0.965\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 120.5pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"23%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eHbA1c(%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 78pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"14.857142857142858%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e6.02\u003c/span\u003e\u003cspan style=\"font-size:16px;font-family:SimSun;\"\u003e±\u003c/span\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New 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style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-family:SimSun;\"\u003e＜\u003c/span\u003e\u003cspan style=\"font-family: \u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0.001\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11.8pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"2.2857142857142856%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75.05pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e5.97\u003c/span\u003e\u003cspan style=\"font-size:16px;font-family:SimSun;\"\u003e±\u003c/span\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e1.01\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"13.571428571428571%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e7.48\u003c/span\u003e\u003cspan style=\"font-size:16px;font-family:SimSun;\"\u003e±\u003c/span\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e1.37\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 49.6pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"9.428571428571429%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-family:SimSun;\"\u003e＜\u003c/span\u003e\u003cspan style=\"font-family: \u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0.001\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 120.5pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"23%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eBlood sugar(mmol/L)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 78pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"14.857142857142858%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e5.59\u003c/span\u003e\u003cspan style=\"font-size:16px;font-family:SimSun;\"\u003e±\u003c/span\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e1.46\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 71.05pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"13.571428571428571%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e7.89\u003c/span\u003e\u003cspan style=\"font-size:16px;font-family:SimSun;\"\u003e±\u003c/span\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e3.04\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 47.6pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"9%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-family:SimSun;\"\u003e＜\u003c/span\u003e\u003cspan style=\"font-family: \u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0.001\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11.8pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"2.2857142857142856%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75.05pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e5.43\u003c/span\u003e\u003cspan style=\"font-size:16px;font-family:SimSun;\"\u003e±\u003c/span\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0.83\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"13.571428571428571%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e7.86\u003c/span\u003e\u003cspan style=\"font-size:16px;font-family:SimSun;\"\u003e±\u003c/span\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e2.77\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 49.6pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"9.428571428571429%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-family:SimSun;\"\u003e＜\u003c/span\u003e\u003cspan style=\"font-family: \u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0.001\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 120.5pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"23%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eSymptoms\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 78pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"14.857142857142858%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 71.05pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"13.571428571428571%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 47.6pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"9%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0.245\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11.8pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"2.2857142857142856%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75.05pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"13.571428571428571%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 49.6pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"9.428571428571429%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0.811\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 120.5pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"23%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;text-indent:6.0pt;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eChest pain\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 78pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"14.857142857142858%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e356(95.4%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 71.05pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"13.571428571428571%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e341(97.2%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 47.6pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"9%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0.456\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11.8pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"2.2857142857142856%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75.05pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e248(96.9%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"13.571428571428571%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e246(96.1%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 49.6pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"9.428571428571429%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0.966\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 120.5pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"23%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;text-indent:12.0pt;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eSA\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 78pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"14.857142857142858%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e142(39.9%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 71.05pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"13.571428571428571%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e126(37.0%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 47.6pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"9%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11.8pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"2.2857142857142856%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75.05pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e98(39.5%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"13.571428571428571%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e96(39.0%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 49.6pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"9.428571428571429%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 120.5pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"23%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;text-indent:12.0pt;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eUA\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 78pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"14.857142857142858%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e133(37.4%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 71.05pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"13.571428571428571%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e124(36.4%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 47.6pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"9%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11.8pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"2.2857142857142856%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75.05pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e90(36.3%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"13.571428571428571%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e92(37.4%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 49.6pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"9.428571428571429%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 120.5pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"23%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;text-indent:12.0pt;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eAMI\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 78pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"14.857142857142858%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e81(22.8%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 71.05pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"13.571428571428571%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e91(26.7%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 47.6pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"9%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11.8pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"2.2857142857142856%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75.05pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e60(24.2%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"13.571428571428571%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e58(23.6%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 49.6pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"9.428571428571429%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 120.5pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"23%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;Others\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 78pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"14.857142857142858%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e17(4.6%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 71.05pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"13.571428571428571%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e10(2.8%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 47.6pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"9%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11.8pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"2.2857142857142856%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75.05pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e8(3.1%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"13.571428571428571%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e10(3.9%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 49.6pt;border: none;padding: 0in 5.4pt;height: 24.4pt;vertical-align: top;\" valign=\"top\" width=\"9.428571428571429%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 120.5pt;border: none;padding: 0in 5.4pt;height: 15.85pt;vertical-align: top;\" valign=\"top\" width=\"23%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eMean LVEF%\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 78pt;border: none;padding: 0in 5.4pt;height: 15.85pt;vertical-align: top;\" valign=\"top\" width=\"14.857142857142858%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e59.13\u003c/span\u003e\u003cspan style=\"font-size:16px;font-family:SimSun;\"\u003e±\u003c/span\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e9.16\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 71.05pt;border: none;padding: 0in 5.4pt;height: 15.85pt;vertical-align: top;\" valign=\"top\" width=\"13.571428571428571%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e58.46\u003c/span\u003e\u003cspan style=\"font-size:16px;font-family:SimSun;\"\u003e±\u003c/span\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e9.29\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 47.6pt;border: none;padding: 0in 5.4pt;height: 15.85pt;vertical-align: top;\" valign=\"top\" width=\"9%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0.364\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11.8pt;border: none;padding: 0in 5.4pt;height: 15.85pt;vertical-align: top;\" valign=\"top\" width=\"2.2857142857142856%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75.05pt;border: none;padding: 0in 5.4pt;height: 15.85pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e59.06\u003c/span\u003e\u003cspan style=\"font-size:16px;font-family:SimSun;\"\u003e±\u003c/span\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e8.96\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border: none;padding: 0in 5.4pt;height: 15.85pt;vertical-align: top;\" valign=\"top\" width=\"13.571428571428571%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e58.65\u003c/span\u003e\u003cspan style=\"font-size:16px;font-family:SimSun;\"\u003e±\u003c/span\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e9.03\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 49.6pt;border: none;padding: 0in 5.4pt;height: 15.85pt;vertical-align: top;\" valign=\"top\" width=\"9.428571428571429%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0.631\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 120.5pt;border: none;padding: 0in 5.4pt;height: 19.75pt;vertical-align: top;\" valign=\"top\" width=\"23%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eDuration after CABG\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 78pt;border: none;padding: 0in 5.4pt;height: 19.75pt;vertical-align: top;\" valign=\"top\" width=\"14.857142857142858%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e4.48\u003c/span\u003e\u003cspan style=\"font-size:16px;font-family:SimSun;\"\u003e±\u003c/span\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e3.43\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 71.05pt;border: none;padding: 0in 5.4pt;height: 19.75pt;vertical-align: top;\" valign=\"top\" width=\"13.571428571428571%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e5.03\u003c/span\u003e\u003cspan style=\"font-size:16px;font-family:SimSun;\"\u003e±\u003c/span\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e3.66\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 47.6pt;border: none;padding: 0in 5.4pt;height: 19.75pt;vertical-align: top;\" valign=\"top\" width=\"9%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0.034\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11.8pt;border: none;padding: 0in 5.4pt;height: 19.75pt;vertical-align: top;\" valign=\"top\" width=\"2.2857142857142856%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75.05pt;border: none;padding: 0in 5.4pt;height: 19.75pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e4.68\u003c/span\u003e\u003cspan style=\"font-size:16px;font-family:SimSun;\"\u003e±\u003c/span\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e3.43\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border: none;padding: 0in 5.4pt;height: 19.75pt;vertical-align: top;\" valign=\"top\" width=\"13.571428571428571%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e4.71\u003c/span\u003e\u003cspan style=\"font-size:16px;font-family:SimSun;\"\u003e±\u003c/span\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e3.52\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 49.6pt;border: none;padding: 0in 5.4pt;height: 19.75pt;vertical-align: top;\" valign=\"top\" width=\"9.428571428571429%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0.917\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 120.5pt;border: none;padding: 0in 5.4pt;height: 19.75pt;vertical-align: top;\" valign=\"top\" width=\"23%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New 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19.75pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border: none;padding: 0in 5.4pt;height: 19.75pt;vertical-align: top;\" valign=\"top\" width=\"13.571428571428571%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 49.6pt;border: none;padding: 0in 5.4pt;height: 19.75pt;vertical-align: top;\" valign=\"top\" width=\"9.428571428571429%\"\u003e\n 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style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e303(81.2%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 71.05pt;border: none;padding: 0in 5.4pt;height: 20.9pt;vertical-align: top;\" valign=\"top\" width=\"13.571428571428571%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e278(79.2%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 47.6pt;border: none;padding: 0in 5.4pt;height: 20.9pt;vertical-align: top;\" valign=\"top\" width=\"9%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0.514\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11.8pt;border: none;padding: 0in 5.4pt;height: 20.9pt;vertical-align: top;\" valign=\"top\" width=\"2.2857142857142856%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75.05pt;border: none;padding: 0in 5.4pt;height: 20.9pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e207(80.9%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border: none;padding: 0in 5.4pt;height: 20.9pt;vertical-align: top;\" valign=\"top\" width=\"13.571428571428571%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e207(80.9%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 49.6pt;border: none;padding: 0in 5.4pt;height: 20.9pt;vertical-align: top;\" valign=\"top\" width=\"9.428571428571429%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e1.000\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 120.5pt;border: none;padding: 0in 5.4pt;height: 19.25pt;vertical-align: top;\" valign=\"top\" width=\"23%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eRelevant NCAs\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 78pt;border: none;padding: 0in 5.4pt;height: 19.25pt;vertical-align: top;\" valign=\"top\" width=\"14.857142857142858%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 71.05pt;border: none;padding: 0in 5.4pt;height: 19.25pt;vertical-align: top;\" valign=\"top\" width=\"13.571428571428571%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 47.6pt;border: none;padding: 0in 5.4pt;height: 19.25pt;vertical-align: top;\" valign=\"top\" width=\"9%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11.8pt;border: none;padding: 0in 5.4pt;height: 19.25pt;vertical-align: top;\" valign=\"top\" width=\"2.2857142857142856%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75.05pt;border: none;padding: 0in 5.4pt;height: 19.25pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border: none;padding: 0in 5.4pt;height: 19.25pt;vertical-align: top;\" valign=\"top\" width=\"13.571428571428571%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 49.6pt;border: none;padding: 0in 5.4pt;height: 19.25pt;vertical-align: top;\" valign=\"top\" width=\"9.428571428571429%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 120.5pt;border: none;padding: 0in 5.4pt;height: 19.75pt;vertical-align: top;\" valign=\"top\" width=\"23%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;text-indent:12.0pt;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eCTO\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 78pt;border: none;padding: 0in 5.4pt;height: 19.75pt;vertical-align: top;\" valign=\"top\" width=\"14.857142857142858%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e194(52.0%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 71.05pt;border: none;padding: 0in 5.4pt;height: 19.75pt;vertical-align: top;\" valign=\"top\" width=\"13.571428571428571%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e176(50.1%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 47.6pt;border: none;padding: 0in 5.4pt;height: 19.75pt;vertical-align: top;\" valign=\"top\" width=\"9%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0.655\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11.8pt;border: none;padding: 0in 5.4pt;height: 19.75pt;vertical-align: top;\" valign=\"top\" width=\"2.2857142857142856%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75.05pt;border: none;padding: 0in 5.4pt;height: 19.75pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e128(50.0%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border: none;padding: 0in 5.4pt;height: 19.75pt;vertical-align: top;\" valign=\"top\" width=\"13.571428571428571%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e127(49.6%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 49.6pt;border: none;padding: 0in 5.4pt;height: 19.75pt;vertical-align: top;\" valign=\"top\" width=\"9.428571428571429%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e1.000\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 120.5pt;border: none;padding: 0in 5.4pt;height: 19.75pt;vertical-align: top;\" valign=\"top\" width=\"23%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;text-indent:12.0pt;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eDiffuse lesions\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 78pt;border: none;padding: 0in 5.4pt;height: 19.75pt;vertical-align: top;\" valign=\"top\" width=\"14.857142857142858%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e56(15.0%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 71.05pt;border: none;padding: 0in 5.4pt;height: 19.75pt;vertical-align: top;\" valign=\"top\" width=\"13.571428571428571%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e53(15.1%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 47.6pt;border: none;padding: 0in 5.4pt;height: 19.75pt;vertical-align: top;\" valign=\"top\" width=\"9%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e1.000\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11.8pt;border: none;padding: 0in 5.4pt;height: 19.75pt;vertical-align: top;\" valign=\"top\" width=\"2.2857142857142856%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75.05pt;border: none;padding: 0in 5.4pt;height: 19.75pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e38(14.8%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border: none;padding: 0in 5.4pt;height: 19.75pt;vertical-align: top;\" valign=\"top\" width=\"13.571428571428571%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e37(14.5%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 49.6pt;border: none;padding: 0in 5.4pt;height: 19.75pt;vertical-align: top;\" valign=\"top\" width=\"9.428571428571429%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e1.000\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 120.5pt;border: none;padding: 0in 5.4pt;height: 19.75pt;vertical-align: top;\" valign=\"top\" width=\"23%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;text-indent:12.0pt;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eBranches\u0026nbsp;involved\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 78pt;border: none;padding: 0in 5.4pt;height: 19.75pt;vertical-align: top;\" valign=\"top\" width=\"14.857142857142858%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e104(27.9%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 71.05pt;border: none;padding: 0in 5.4pt;height: 19.75pt;vertical-align: top;\" valign=\"top\" width=\"13.571428571428571%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e114(32.5%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 47.6pt;border: none;padding: 0in 5.4pt;height: 19.75pt;vertical-align: top;\" valign=\"top\" width=\"9%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0.195\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11.8pt;border: none;padding: 0in 5.4pt;height: 19.75pt;vertical-align: top;\" valign=\"top\" width=\"2.2857142857142856%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75.05pt;border: none;padding: 0in 5.4pt;height: 19.75pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e70(27.3%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border: none;padding: 0in 5.4pt;height: 19.75pt;vertical-align: top;\" valign=\"top\" width=\"13.571428571428571%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e73(28.5%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 49.6pt;border: none;padding: 0in 5.4pt;height: 19.75pt;vertical-align: top;\" valign=\"top\" width=\"9.428571428571429%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0.844\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 120.5pt;border: none;padding: 0in 5.4pt;height: 19.75pt;vertical-align: top;\" valign=\"top\" width=\"23%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;text-indent:12.0pt;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eOpening involved\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 78pt;border: none;padding: 0in 5.4pt;height: 19.75pt;vertical-align: top;\" valign=\"top\" width=\"14.857142857142858%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e117(31.4%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 71.05pt;border: none;padding: 0in 5.4pt;height: 19.75pt;vertical-align: top;\" valign=\"top\" width=\"13.571428571428571%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e106(30.2%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 47.6pt;border: none;padding: 0in 5.4pt;height: 19.75pt;vertical-align: top;\" valign=\"top\" width=\"9%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11.8pt;border: none;padding: 0in 5.4pt;height: 19.75pt;vertical-align: top;\" valign=\"top\" width=\"2.2857142857142856%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75.05pt;border: none;padding: 0in 5.4pt;height: 19.75pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e81(31.6%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border: none;padding: 0in 5.4pt;height: 19.75pt;vertical-align: top;\" valign=\"top\" width=\"13.571428571428571%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e81(31.6%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 49.6pt;border: none;padding: 0in 5.4pt;height: 19.75pt;vertical-align: top;\" valign=\"top\" width=\"9.428571428571429%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e1.000\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 120.5pt;border: none;padding: 0in 5.4pt;height: 19.75pt;vertical-align: top;\" valign=\"top\" width=\"23%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eIschemic territory\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 78pt;border: none;padding: 0in 5.4pt;height: 19.75pt;vertical-align: top;\" valign=\"top\" width=\"14.857142857142858%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 71.05pt;border: none;padding: 0in 5.4pt;height: 19.75pt;vertical-align: top;\" valign=\"top\" width=\"13.571428571428571%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 47.6pt;border: none;padding: 0in 5.4pt;height: 19.75pt;vertical-align: top;\" valign=\"top\" width=\"9%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0.885\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11.8pt;border: none;padding: 0in 5.4pt;height: 19.75pt;vertical-align: top;\" valign=\"top\" width=\"2.2857142857142856%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75.05pt;border: none;padding: 0in 5.4pt;height: 19.75pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border: none;padding: 0in 5.4pt;height: 19.75pt;vertical-align: top;\" valign=\"top\" width=\"13.571428571428571%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 49.6pt;border: none;padding: 0in 5.4pt;height: 19.75pt;vertical-align: top;\" valign=\"top\" width=\"9.428571428571429%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0.649\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 120.5pt;border: none;padding: 0in 5.4pt;height: 19.75pt;vertical-align: top;\" valign=\"top\" width=\"23%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;text-indent:12.0pt;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eOne territory\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 78pt;border: none;padding: 0in 5.4pt;height: 19.75pt;vertical-align: top;\" valign=\"top\" width=\"14.857142857142858%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e142(38.1%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 71.05pt;border: none;padding: 0in 5.4pt;height: 19.75pt;vertical-align: top;\" valign=\"top\" width=\"13.571428571428571%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e137(39.0%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 47.6pt;border: none;padding: 0in 5.4pt;height: 19.75pt;vertical-align: top;\" valign=\"top\" width=\"9%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11.8pt;border: none;padding: 0in 5.4pt;height: 19.75pt;vertical-align: top;\" valign=\"top\" width=\"2.2857142857142856%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75.05pt;border: none;padding: 0in 5.4pt;height: 19.75pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e102(39.8%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border: none;padding: 0in 5.4pt;height: 19.75pt;vertical-align: top;\" valign=\"top\" width=\"13.571428571428571%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e99(38.7%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 49.6pt;border: none;padding: 0in 5.4pt;height: 19.75pt;vertical-align: top;\" valign=\"top\" width=\"9.428571428571429%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 120.5pt;border: none;padding: 0in 5.4pt;height: 17.05pt;vertical-align: top;\" valign=\"top\" width=\"23%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;text-indent:12.0pt;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eTwo territories\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 78pt;border: none;padding: 0in 5.4pt;height: 17.05pt;vertical-align: top;\" valign=\"top\" width=\"14.857142857142858%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e172(46.1%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 71.05pt;border: none;padding: 0in 5.4pt;height: 17.05pt;vertical-align: top;\" valign=\"top\" width=\"13.571428571428571%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e163(46.4%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 47.6pt;border: none;padding: 0in 5.4pt;height: 17.05pt;vertical-align: top;\" valign=\"top\" width=\"9%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11.8pt;border: none;padding: 0in 5.4pt;height: 17.05pt;vertical-align: top;\" valign=\"top\" width=\"2.2857142857142856%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75.05pt;border: none;padding: 0in 5.4pt;height: 17.05pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e125(48.8%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border: none;padding: 0in 5.4pt;height: 17.05pt;vertical-align: top;\" valign=\"top\" width=\"13.571428571428571%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e121 (47.3%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 49.6pt;border: none;padding: 0in 5.4pt;height: 17.05pt;vertical-align: top;\" valign=\"top\" width=\"9.428571428571429%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 120.5pt;border: none;padding: 0in 5.4pt;height: 19.75pt;vertical-align: top;\" valign=\"top\" width=\"23%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;text-indent:12.0pt;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eThree territories\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 78pt;border: none;padding: 0in 5.4pt;height: 19.75pt;vertical-align: top;\" valign=\"top\" width=\"14.857142857142858%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e59(15.8%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 71.05pt;border: none;padding: 0in 5.4pt;height: 19.75pt;vertical-align: top;\" valign=\"top\" width=\"13.571428571428571%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e51(14.5%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 47.6pt;border: none;padding: 0in 5.4pt;height: 19.75pt;vertical-align: top;\" valign=\"top\" width=\"9%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11.8pt;border: none;padding: 0in 5.4pt;height: 19.75pt;vertical-align: top;\" valign=\"top\" width=\"2.2857142857142856%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75.05pt;border: none;padding: 0in 5.4pt;height: 19.75pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e29(11.3%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border: none;padding: 0in 5.4pt;height: 19.75pt;vertical-align: top;\" valign=\"top\" width=\"13.571428571428571%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e36(14.1%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 49.6pt;border: none;padding: 0in 5.4pt;height: 19.75pt;vertical-align: top;\" valign=\"top\" width=\"9.428571428571429%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 120.5pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid black;padding: 0in 5.4pt;height: 19.75pt;vertical-align: top;\" valign=\"top\" width=\"23%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;text-indent:12.0pt;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;color:black;\"\u003eSYNTAX Score I\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 78pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid black;padding: 0in 5.4pt;height: 19.75pt;vertical-align: top;\" valign=\"top\" width=\"14.857142857142858%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;color:black;\"\u003e42.0\u003c/span\u003e\u003cspan style=\"font-size:16px;font-family:SimSun;color:black;\"\u003e±\u003c/span\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;color:black;\"\u003e13.0\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 71.05pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid black;padding: 0in 5.4pt;height: 19.75pt;vertical-align: top;\" valign=\"top\" width=\"13.571428571428571%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;color:black;\"\u003e43.4\u003c/span\u003e\u003cspan style=\"font-size:16px;font-family:SimSun;color:black;\"\u003e±\u003c/span\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;color:black;\"\u003e12.7\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 47.6pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid black;padding: 0in 5.4pt;height: 19.75pt;vertical-align: top;\" valign=\"top\" width=\"9%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;color:black;\"\u003e0.145\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 11.8pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid black;padding: 0in 5.4pt;height: 19.75pt;vertical-align: top;\" valign=\"top\" width=\"2.2857142857142856%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;color:black;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75.05pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid black;padding: 0in 5.4pt;height: 19.75pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;color:black;\"\u003e42.1\u003c/span\u003e\u003cspan style=\"font-size:16px;font-family:SimSun;color:black;\"\u003e±\u003c/span\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;color:black;\"\u003e13.1\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid black;padding: 0in 5.4pt;height: 19.75pt;vertical-align: top;\" valign=\"top\" width=\"13.571428571428571%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;color:black;\"\u003e42.8\u003c/span\u003e\u003cspan style=\"font-size:16px;font-family:SimSun;color:black;\"\u003e±\u003c/span\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;color:black;\"\u003e12.9\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 49.6pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid black;padding: 0in 5.4pt;height: 19.75pt;vertical-align: top;\" valign=\"top\" width=\"9.428571428571429%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;color:black;\"\u003e0.575\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003c/tbody\u003e\n\u003c/table\u003e\n\u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;color:black;background:white;\"\u003eAMI=acute myocardial infarction; BMI=body mass index; CABG=coronary artery bypass graft\u003c/span\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e;\u003c/span\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;color:black;background:white;\"\u003e\u0026nbsp;CTO=chroni\u003c/span\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;color:black;background:white;\"\u003ec total occlusion;\u003c/span\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;color:black;background:white;\"\u003e\u0026nbsp;CVA=cerebrovascular accident;\u0026nbsp;\u003c/span\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eDM= diabetes mellitus;\u003c/span\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;color:black;background:white;\"\u003e\u0026nbsp;HbA1c=\u003c/span\u003e \u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;color:black;background:white;\"\u003eglycosylated hemoglobin; HF=heart failure; LVEF= left ventricular ejection fraction; NCA=native coronary artery\u0026nbsp;\u003c/span\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003ePCI= percutaneous coronary intervention\u003c/span\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;color:black;background:white;\"\u003e; PVD=peripheral vascular disease; SA=stable angina; SVG= saphenous vein graft ; UA=unstable angina\u003c/span\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;color:black;background:white;\"\u003e.\u003c/span\u003e\u003c/p\u003e\u003c/br\u003e\u003c/br\u003e\n\u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cstrong\u003e\u003cspan style=\"font-size: 16px; font-family: \u0026quot;Times New Roman\u0026quot;, serif; color: rgb(0, 0, 0);\"\u003eTable 2\u003c/span\u003e\u003c/strong\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;Procedural baseline characteristics of\u0026nbsp;patients\u0026nbsp;with prior CABG (n=724).\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n\u003ctable border=\"1\" cellpadding=\"0\" cellspacing=\"0\" style=\"margin-left:-30.05pt;border-collapse:collapse;border:none;\" width=\"690\"\u003e\n \u003ctbody\u003e\n \u003ctr\u003e\n \u003ctd rowspan=\"3\" style=\"width: 141.8pt;border-top: 1pt solid black;border-left: none;border-bottom: 1pt solid black;border-right: none;padding: 0in 5.4pt;height: 22.1pt;vertical-align: top;\" valign=\"top\" width=\"27.391304347826086%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:center;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;margin-top:12.0pt;line-height:300%;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;line-height:300%;font-family: \u0026quot;Times New Roman\u0026quot;,serif;\"\u003eVariable\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"3\" style=\"width: 177.15pt;border-top: 1pt solid black;border-left: none;border-bottom: 1pt solid black;border-right: none;padding: 0in 5.4pt;height: 22.1pt;vertical-align: top;\" valign=\"top\" width=\"34.20289855072464%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;text-indent:42.0pt;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eUnmatched\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd rowspan=\"3\" style=\"width: 14.2pt;border-top: 1pt solid black;border-left: none;border-bottom: 1pt solid black;border-right: none;padding: 0in 5.4pt;height: 22.1pt;vertical-align: top;\" valign=\"top\" width=\"2.753623188405797%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;text-indent:1.0in;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n 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style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eNo DM\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.8pt;border: none;padding: 0in 5.4pt;height: 20.2pt;vertical-align: top;\" valign=\"top\" width=\"17.634854771784234%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;text-indent:12.0pt;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eDM\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd rowspan=\"2\" style=\"width: 42.5pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid black;padding: 0in 5.4pt;height: 20.2pt;vertical-align: top;\" valign=\"top\" width=\"11.825726141078839%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;margin-top:12.0pt;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eP value\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border: none;padding: 0in 5.4pt;height: 20.2pt;vertical-align: top;\" valign=\"top\" width=\"19.70954356846473%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eNo DM\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.85pt;border: none;padding: 0in 5.4pt;height: 20.2pt;vertical-align: top;\" valign=\"top\" width=\"19.502074688796682%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;text-indent:12.0pt;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eDM\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd rowspan=\"2\" style=\"width: 42.5pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid black;padding: 0in 5.4pt;height: 20.2pt;vertical-align: top;\" valign=\"top\" width=\"11.825726141078839%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;margin-top:12.0pt;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eP value\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 70.85pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid black;padding: 0in 5.4pt;height: 20.7pt;vertical-align: top;\" valign=\"top\" width=\"25.543478260869566%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;text-indent:12.0pt;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003en=373\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.8pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid black;padding: 0in 5.4pt;height: 20.7pt;vertical-align: top;\" valign=\"top\" width=\"23.097826086956523%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003en=351\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid black;padding: 0in 5.4pt;height: 20.7pt;vertical-align: top;\" valign=\"top\" width=\"25.815217391304348%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;text-indent:12.0pt;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003en=256\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.85pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid black;padding: 0in 5.4pt;height: 20.7pt;vertical-align: top;\" valign=\"top\" width=\"25.543478260869566%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;text-indent:6.0pt;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003en=256\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 141.8pt;border: none;padding: 0in 5.4pt;height: 24.65pt;vertical-align: top;\" valign=\"top\" width=\"27.391304347826086%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eFemoral access\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.85pt;border: none;padding: 0in 5.4pt;height: 24.65pt;vertical-align: top;\" valign=\"top\" width=\"13.623188405797102%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e201(53.9%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.8pt;border: none;padding: 0in 5.4pt;height: 24.65pt;vertical-align: top;\" valign=\"top\" width=\"12.318840579710145%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e185(52.7%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42.5pt;border: none;padding: 0in 5.4pt;height: 24.65pt;vertical-align: top;\" valign=\"top\" width=\"8.26086956521739%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0.766\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 14.2pt;border: none;padding: 0in 5.4pt;height: 24.65pt;vertical-align: top;\" valign=\"top\" width=\"2.753623188405797%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border: none;padding: 0in 5.4pt;height: 24.65pt;vertical-align: top;\" valign=\"top\" width=\"13.768115942028986%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e138(53.9%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.85pt;border: none;padding: 0in 5.4pt;height: 24.65pt;vertical-align: top;\" valign=\"top\" width=\"13.623188405797102%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e132(51.6%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42.5pt;border: none;padding: 0in 5.4pt;height: 24.65pt;vertical-align: top;\" valign=\"top\" width=\"8.26086956521739%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0.658\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 141.8pt;border: none;padding: 0in 5.4pt;height: 24.65pt;vertical-align: top;\" valign=\"top\" width=\"27.391304347826086%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eTarget vessel\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.85pt;border: none;padding: 0in 5.4pt;height: 24.65pt;vertical-align: top;\" valign=\"top\" width=\"13.623188405797102%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.8pt;border: none;padding: 0in 5.4pt;height: 24.65pt;vertical-align: top;\" valign=\"top\" width=\"12.318840579710145%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42.5pt;border: none;padding: 0in 5.4pt;height: 24.65pt;vertical-align: top;\" valign=\"top\" width=\"8.26086956521739%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e1.000\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 14.2pt;border: none;padding: 0in 5.4pt;height: 24.65pt;vertical-align: top;\" valign=\"top\" width=\"2.753623188405797%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border: none;padding: 0in 5.4pt;height: 24.65pt;vertical-align: top;\" valign=\"top\" width=\"13.768115942028986%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.85pt;border: none;padding: 0in 5.4pt;height: 24.65pt;vertical-align: top;\" valign=\"top\" width=\"13.623188405797102%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42.5pt;border: none;padding: 0in 5.4pt;height: 24.65pt;vertical-align: top;\" valign=\"top\" width=\"8.26086956521739%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0.894\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 141.8pt;border: none;padding: 0in 5.4pt;height: 24.65pt;vertical-align: top;\" valign=\"top\" width=\"27.391304347826086%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;text-indent:6.0pt;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eNCA only\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.85pt;border: none;padding: 0in 5.4pt;height: 24.65pt;vertical-align: top;\" valign=\"top\" width=\"13.623188405797102%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e327(87.7%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.8pt;border: none;padding: 0in 5.4pt;height: 24.65pt;vertical-align: top;\" valign=\"top\" width=\"12.318840579710145%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e308(87.7%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42.5pt;border: none;padding: 0in 5.4pt;height: 24.65pt;vertical-align: top;\" valign=\"top\" width=\"8.26086956521739%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 14.2pt;border: none;padding: 0in 5.4pt;height: 24.65pt;vertical-align: top;\" valign=\"top\" width=\"2.753623188405797%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border: none;padding: 0in 5.4pt;height: 24.65pt;vertical-align: top;\" valign=\"top\" width=\"13.768115942028986%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e223(87.1%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.85pt;border: none;padding: 0in 5.4pt;height: 24.65pt;vertical-align: top;\" valign=\"top\" width=\"13.623188405797102%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e225(87.9%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42.5pt;border: none;padding: 0in 5.4pt;height: 24.65pt;vertical-align: top;\" valign=\"top\" width=\"8.26086956521739%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 141.8pt;border: none;padding: 0in 5.4pt;height: 19.85pt;vertical-align: top;\" valign=\"top\" width=\"27.391304347826086%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;text-indent:6.0pt;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eNCA and Graft\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.85pt;border: none;padding: 0in 5.4pt;height: 19.85pt;vertical-align: top;\" valign=\"top\" width=\"13.623188405797102%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e46(12.3%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.8pt;border: none;padding: 0in 5.4pt;height: 19.85pt;vertical-align: top;\" valign=\"top\" width=\"12.318840579710145%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e43(12.3%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42.5pt;border: none;padding: 0in 5.4pt;height: 19.85pt;vertical-align: top;\" valign=\"top\" width=\"8.26086956521739%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 14.2pt;border: none;padding: 0in 5.4pt;height: 19.85pt;vertical-align: top;\" valign=\"top\" width=\"2.753623188405797%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border: none;padding: 0in 5.4pt;height: 19.85pt;vertical-align: top;\" valign=\"top\" width=\"13.768115942028986%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e35(12.9%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.85pt;border: none;padding: 0in 5.4pt;height: 19.85pt;vertical-align: top;\" valign=\"top\" width=\"13.623188405797102%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e32(12.1%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42.5pt;border: none;padding: 0in 5.4pt;height: 19.85pt;vertical-align: top;\" valign=\"top\" width=\"8.26086956521739%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 141.8pt;border: none;padding: 0in 5.4pt;height: 24.65pt;vertical-align: top;\" valign=\"top\" width=\"27.391304347826086%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eMulti-vessel PCI\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.85pt;border: none;padding: 0in 5.4pt;height: 24.65pt;vertical-align: top;\" valign=\"top\" width=\"13.623188405797102%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e122(32.7%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.8pt;border: none;padding: 0in 5.4pt;height: 24.65pt;vertical-align: top;\" valign=\"top\" width=\"12.318840579710145%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e90(25.6%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42.5pt;border: none;padding: 0in 5.4pt;height: 24.65pt;vertical-align: top;\" valign=\"top\" width=\"8.26086956521739%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0.041\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 14.2pt;border: none;padding: 0in 5.4pt;height: 24.65pt;vertical-align: top;\" valign=\"top\" width=\"2.753623188405797%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border: none;padding: 0in 5.4pt;height: 24.65pt;vertical-align: top;\" valign=\"top\" width=\"13.768115942028986%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e73(28.5%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.85pt;border: none;padding: 0in 5.4pt;height: 24.65pt;vertical-align: top;\" valign=\"top\" width=\"13.623188405797102%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e70(27.3%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42.5pt;border: none;padding: 0in 5.4pt;height: 24.65pt;vertical-align: top;\" valign=\"top\" width=\"8.26086956521739%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0.844\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 141.8pt;border: none;padding: 0in 5.4pt;height: 16.95pt;vertical-align: top;\" valign=\"top\" width=\"27.391304347826086%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eStent\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.85pt;border: none;padding: 0in 5.4pt;height: 16.95pt;vertical-align: top;\" valign=\"top\" width=\"13.623188405797102%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.8pt;border: none;padding: 0in 5.4pt;height: 16.95pt;vertical-align: top;\" valign=\"top\" width=\"12.318840579710145%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;text-indent:6.0pt;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42.5pt;border: none;padding: 0in 5.4pt;height: 16.95pt;vertical-align: top;\" valign=\"top\" width=\"8.26086956521739%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 14.2pt;border: none;padding: 0in 5.4pt;height: 16.95pt;vertical-align: top;\" valign=\"top\" width=\"2.753623188405797%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border: none;padding: 0in 5.4pt;height: 16.95pt;vertical-align: top;\" valign=\"top\" width=\"13.768115942028986%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.85pt;border: none;padding: 0in 5.4pt;height: 16.95pt;vertical-align: top;\" valign=\"top\" width=\"13.623188405797102%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;text-indent:6.0pt;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42.5pt;border: none;padding: 0in 5.4pt;height: 16.95pt;vertical-align: top;\" valign=\"top\" width=\"8.26086956521739%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 141.8pt;border: none;padding: 0in 5.4pt;height: 21.05pt;vertical-align: top;\" valign=\"top\" width=\"27.391304347826086%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;text-indent:6.0pt;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eMean number of stents\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.85pt;border: none;padding: 0in 5.4pt;height: 21.05pt;vertical-align: top;\" valign=\"top\" width=\"13.623188405797102%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e1.88\u003c/span\u003e\u003cspan style=\"font-size:16px;font-family:SimSun;\"\u003e±\u003c/span\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e1.13\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.8pt;border: none;padding: 0in 5.4pt;height: 21.05pt;vertical-align: top;\" valign=\"top\" width=\"12.318840579710145%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e1.87\u003c/span\u003e\u003cspan style=\"font-size:16px;font-family:SimSun;\"\u003e±\u003c/span\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e1.09\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42.5pt;border: none;padding: 0in 5.4pt;height: 21.05pt;vertical-align: top;\" valign=\"top\" width=\"8.26086956521739%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0.874\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 14.2pt;border: none;padding: 0in 5.4pt;height: 21.05pt;vertical-align: top;\" valign=\"top\" width=\"2.753623188405797%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border: none;padding: 0in 5.4pt;height: 21.05pt;vertical-align: top;\" valign=\"top\" width=\"13.768115942028986%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e1.83\u003c/span\u003e\u003cspan style=\"font-size:16px;font-family:SimSun;\"\u003e±\u003c/span\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e1.11\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.85pt;border: none;padding: 0in 5.4pt;height: 21.05pt;vertical-align: top;\" valign=\"top\" width=\"13.623188405797102%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e1.89\u003c/span\u003e\u003cspan style=\"font-size:16px;font-family:SimSun;\"\u003e±\u003c/span\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e1.12\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42.5pt;border: none;padding: 0in 5.4pt;height: 21.05pt;vertical-align: top;\" valign=\"top\" width=\"8.26086956521739%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0.558\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 141.8pt;border: none;padding: 0in 5.4pt;height: 21.35pt;vertical-align: top;\" valign=\"top\" width=\"27.391304347826086%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;text-indent:12.0pt;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eFirst-generation DES\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.85pt;border: none;padding: 0in 5.4pt;height: 21.35pt;vertical-align: top;\" valign=\"top\" width=\"13.623188405797102%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e236(63.3%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.8pt;border: none;padding: 0in 5.4pt;height: 21.35pt;vertical-align: top;\" valign=\"top\" width=\"12.318840579710145%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e220(62.7%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42.5pt;border: none;padding: 0in 5.4pt;height: 21.35pt;vertical-align: top;\" valign=\"top\" width=\"8.26086956521739%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0.878\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 14.2pt;border: none;padding: 0in 5.4pt;height: 21.35pt;vertical-align: top;\" valign=\"top\" width=\"2.753623188405797%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border: none;padding: 0in 5.4pt;height: 21.35pt;vertical-align: top;\" valign=\"top\" width=\"13.768115942028986%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e159(62.1%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.85pt;border: none;padding: 0in 5.4pt;height: 21.35pt;vertical-align: top;\" valign=\"top\" width=\"13.623188405797102%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e166(64.8%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42.5pt;border: none;padding: 0in 5.4pt;height: 21.35pt;vertical-align: top;\" valign=\"top\" width=\"8.26086956521739%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0.582\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 141.8pt;border: none;padding: 0in 5.4pt;height: 21.3pt;vertical-align: top;\" valign=\"top\" width=\"27.391304347826086%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;text-indent:12.0pt;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eSecond-generation DES\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.85pt;border: none;padding: 0in 5.4pt;height: 21.3pt;vertical-align: top;\" valign=\"top\" width=\"13.623188405797102%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e159(42.6%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.8pt;border: none;padding: 0in 5.4pt;height: 21.3pt;vertical-align: top;\" valign=\"top\" width=\"12.318840579710145%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e147(41.9%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42.5pt;border: none;padding: 0in 5.4pt;height: 21.3pt;vertical-align: top;\" valign=\"top\" width=\"8.26086956521739%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0.880\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 14.2pt;border: none;padding: 0in 5.4pt;height: 21.3pt;vertical-align: top;\" valign=\"top\" width=\"2.753623188405797%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border: none;padding: 0in 5.4pt;height: 21.3pt;vertical-align: top;\" valign=\"top\" width=\"13.768115942028986%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e107(41.8%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.85pt;border: none;padding: 0in 5.4pt;height: 21.3pt;vertical-align: top;\" valign=\"top\" width=\"13.623188405797102%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e106(41.4%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42.5pt;border: none;padding: 0in 5.4pt;height: 21.3pt;vertical-align: top;\" valign=\"top\" width=\"8.26086956521739%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e1.000\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 141.8pt;border: none;padding: 0in 5.4pt;height: 21.3pt;vertical-align: top;\" valign=\"top\" width=\"27.391304347826086%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003ePTCA\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.85pt;border: none;padding: 0in 5.4pt;height: 21.3pt;vertical-align: top;\" valign=\"top\" width=\"13.623188405797102%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e40(10.7%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.8pt;border: none;padding: 0in 5.4pt;height: 21.3pt;vertical-align: top;\" valign=\"top\" width=\"12.318840579710145%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e30(8.5%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42.5pt;border: none;padding: 0in 5.4pt;height: 21.3pt;vertical-align: top;\" valign=\"top\" width=\"8.26086956521739%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0.379\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n 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Roman\u0026quot;,serif;\"\u003e19(7.4%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.85pt;border: none;padding: 0in 5.4pt;height: 21.3pt;vertical-align: top;\" valign=\"top\" width=\"13.623188405797102%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e23(9.0%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42.5pt;border: none;padding: 0in 5.4pt;height: 21.3pt;vertical-align: top;\" valign=\"top\" width=\"8.26086956521739%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan 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42.5pt;border: none;padding: 0in 5.4pt;height: 21.3pt;vertical-align: top;\" valign=\"top\" width=\"8.26086956521739%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0.835\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 141.8pt;border: none;padding: 0in 5.4pt;height: 21.55pt;vertical-align: top;\" valign=\"top\" width=\"27.391304347826086%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New 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style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e1.000\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 141.8pt;border: none;padding: 0in 5.4pt;height: 21.4pt;vertical-align: top;\" valign=\"top\" width=\"27.391304347826086%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eAspiration of thrombus\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.85pt;border: none;padding: 0in 5.4pt;height: 21.4pt;vertical-align: top;\" valign=\"top\" width=\"13.623188405797102%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e2(0.5%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.8pt;border: none;padding: 0in 5.4pt;height: 21.4pt;vertical-align: top;\" valign=\"top\" width=\"12.318840579710145%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e3(0.9%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42.5pt;border: none;padding: 0in 5.4pt;height: 21.4pt;vertical-align: top;\" valign=\"top\" 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style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e368(98.7%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.8pt;border: none;padding: 0in 5.4pt;height: 17.65pt;vertical-align: top;\" valign=\"top\" width=\"12.318840579710145%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e345(98.3%))\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42.5pt;border: none;padding: 0in 5.4pt;height: 17.65pt;vertical-align: top;\" valign=\"top\" 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style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e300(85.5%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42.5pt;border: none;padding: 0in 5.4pt;height: 17.65pt;vertical-align: top;\" valign=\"top\" width=\"8.26086956521739%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0.519\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 14.2pt;border: none;padding: 0in 5.4pt;height: 17.65pt;vertical-align: top;\" valign=\"top\" width=\"2.753623188405797%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border: none;padding: 0in 5.4pt;height: 17.65pt;vertical-align: top;\" valign=\"top\" width=\"13.768115942028986%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e200(78.1%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.85pt;border: none;padding: 0in 5.4pt;height: 17.65pt;vertical-align: top;\" valign=\"top\" width=\"13.623188405797102%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e203(79.3%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42.5pt;border: none;padding: 0in 5.4pt;height: 17.65pt;vertical-align: top;\" valign=\"top\" width=\"8.26086956521739%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0.829\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 141.8pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid black;padding: 0in 5.4pt;height: 17.65pt;vertical-align: top;\" valign=\"top\" width=\"27.391304347826086%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;text-indent:6.0pt;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eBeta blockers\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.85pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid black;padding: 0in 5.4pt;height: 17.65pt;vertical-align: top;\" valign=\"top\" width=\"13.623188405797102%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e289(77.5%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.8pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid black;padding: 0in 5.4pt;height: 17.65pt;vertical-align: top;\" valign=\"top\" width=\"12.318840579710145%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e277(78.9%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42.5pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid black;padding: 0in 5.4pt;height: 17.65pt;vertical-align: top;\" valign=\"top\" width=\"8.26086956521739%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0.654\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 14.2pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid black;padding: 0in 5.4pt;height: 17.65pt;vertical-align: top;\" valign=\"top\" width=\"2.753623188405797%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid black;padding: 0in 5.4pt;height: 17.65pt;vertical-align: top;\" valign=\"top\" width=\"13.768115942028986%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e220(85.9%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.85pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid black;padding: 0in 5.4pt;height: 17.65pt;vertical-align: top;\" valign=\"top\" width=\"13.623188405797102%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e221(86.3%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42.5pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid black;padding: 0in 5.4pt;height: 17.65pt;vertical-align: top;\" valign=\"top\" width=\"8.26086956521739%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e1.000\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003c/tbody\u003e\n\u003c/table\u003e\n\u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size: 16px; font-family: \u0026quot;Times New Roman\u0026quot;, serif;\"\u003eCABG=coronary artery bypass graft\u003c/span\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e; DES=drug-eluting stent; DM= diabetes mellitus; EPD=embolic protection devices; IVUS= intravascular ultrasound; NCA= native coronary artery; PCI=percutaneous coronary intervention;\u0026nbsp;\u003c/span\u003e\u003cspan style=\"font-size: 16px; font-family: \u0026quot;Times New Roman\u0026quot;, serif; background: white;\"\u003ePTCA=\u003c/span\u003e\u003cspan style=\"font-size:16px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003cspan style=\"font-size: 16px; font-family: \u0026quot;Times New Roman\u0026quot;, serif; color: rgb(0, 0, 0); background: white;\"\u003epercutaneous coronary angioplasty.\u003c/span\u003e\u003c/p\u003e\u003c/br\u003e\u003c/br\u003e\n\u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cstrong\u003e\u003cspan style=\"font-size: 16px; font-family: \u0026quot;Times New Roman\u0026quot;, serif; color: rgb(0, 0, 0);\"\u003eTable 3\u0026nbsp;\u003c/span\u003e\u003c/strong\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eProcedure-related complications of\u0026nbsp;patients\u0026nbsp;with prior CABG (n=724).\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n\u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n\u003ctable border=\"1\" cellpadding=\"0\" cellspacing=\"0\" style=\"margin-left:-30.05pt;border-collapse:collapse;border:none;\" width=\"662\"\u003e\n \u003ctbody\u003e\n \u003ctr\u003e\n \u003ctd rowspan=\"3\" style=\"width: 113.45pt;border-top: 1pt solid black;border-left: none;border-bottom: 1pt solid black;border-right: none;padding: 0in 5.4pt;height: 20.95pt;vertical-align: top;\" valign=\"top\" width=\"22.844175491679273%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:center;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;margin-top:12.0pt;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eOutcomes\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"3\" style=\"width: 170.1pt;border-top: 1pt solid black;border-left: none;border-bottom: 1pt solid black;border-right: none;padding: 0in 5.4pt;height: 20.95pt;vertical-align: top;\" valign=\"top\" width=\"34.341906202723145%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;text-indent:.5in;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eUnmatched\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd rowspan=\"3\" style=\"width: 21.25pt;border-top: 1pt solid black;border-left: none;border-bottom: 1pt solid black;border-right: none;padding: 0in 5.4pt;height: 20.95pt;vertical-align: top;\" valign=\"top\" width=\"4.236006051437216%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;text-indent:1.0in;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"3\" style=\"width: 191.35pt;border-top: 1pt solid black;border-left: none;border-bottom: 1pt solid black;border-right: none;padding: 0in 5.4pt;height: 20.95pt;vertical-align: top;\" valign=\"top\" width=\"38.57791225416036%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;text-indent:1.0in;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eMatched\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 70.85pt;border: none;padding: 0in 5.4pt;height: 19.15pt;vertical-align: top;\" valign=\"top\" width=\"19.502074688796682%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eNo DM\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: none;padding: 0in 5.4pt;height: 19.15pt;vertical-align: top;\" valign=\"top\" width=\"15.767634854771785%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;text-indent:12.0pt;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eDM\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd rowspan=\"2\" style=\"width: 42.55pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid black;padding: 0in 5.4pt;height: 19.15pt;vertical-align: top;\" valign=\"top\" width=\"11.825726141078839%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eP value\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.85pt;border: none;padding: 0in 5.4pt;height: 19.15pt;vertical-align: top;\" valign=\"top\" width=\"19.502074688796682%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eNo DM\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.8pt;border: none;padding: 0in 5.4pt;height: 19.15pt;vertical-align: top;\" valign=\"top\" width=\"17.634854771784234%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;text-indent:12.0pt;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eDM\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd rowspan=\"2\" style=\"width: 56.7pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid black;padding: 0in 5.4pt;height: 19.15pt;vertical-align: top;\" valign=\"top\" width=\"15.767634854771785%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;margin-top:12.0pt;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eP value\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 70.85pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid black;padding: 0in 5.4pt;height: 16.65pt;vertical-align: top;\" valign=\"top\" width=\"26.93409742120344%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;text-indent:12.0pt;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003en=373\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid black;padding: 0in 5.4pt;height: 16.65pt;vertical-align: top;\" valign=\"top\" width=\"21.77650429799427%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003en=351\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.85pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid black;padding: 0in 5.4pt;height: 16.65pt;vertical-align: top;\" valign=\"top\" width=\"26.93409742120344%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003en=256\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.8pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid black;padding: 0in 5.4pt;height: 16.65pt;vertical-align: top;\" valign=\"top\" width=\"24.355300859598852%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003en=256\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n 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Roman\u0026quot;,serif;\"\u003e0(0.0%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: none;padding: 0in 5.4pt;height: 23.35pt;vertical-align: top;\" valign=\"top\" width=\"11.497730711043873%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e2(0.6%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42.55pt;border: none;padding: 0in 5.4pt;height: 23.35pt;vertical-align: top;\" valign=\"top\" width=\"8.623298033282905%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0.235\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 21.25pt;border: none;padding: 0in 5.4pt;height: 23.35pt;vertical-align: top;\" valign=\"top\" width=\"4.236006051437216%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.85pt;border: none;padding: 0in 5.4pt;height: 23.35pt;vertical-align: top;\" valign=\"top\" width=\"14.22087745839637%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0(0.0%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.8pt;border: none;padding: 0in 5.4pt;height: 23.35pt;vertical-align: top;\" valign=\"top\" width=\"12.85930408472012%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e1(0.4%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: none;padding: 0in 5.4pt;height: 23.35pt;vertical-align: top;\" valign=\"top\" width=\"11.497730711043873%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e1.000\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 113.45pt;border: none;padding: 0in 5.4pt;height: 31.65pt;vertical-align: top;\" valign=\"top\" width=\"22.844175491679273%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eProcedural complications\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.85pt;border: none;padding: 0in 5.4pt;height: 31.65pt;vertical-align: top;\" valign=\"top\" width=\"14.22087745839637%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: none;padding: 0in 5.4pt;height: 31.65pt;vertical-align: top;\" valign=\"top\" width=\"11.497730711043873%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42.55pt;border: none;padding: 0in 5.4pt;height: 31.65pt;vertical-align: top;\" valign=\"top\" width=\"8.623298033282905%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 21.25pt;border: none;padding: 0in 5.4pt;height: 31.65pt;vertical-align: top;\" valign=\"top\" width=\"4.236006051437216%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.85pt;border: none;padding: 0in 5.4pt;height: 31.65pt;vertical-align: top;\" valign=\"top\" width=\"14.22087745839637%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.8pt;border: none;padding: 0in 5.4pt;height: 31.65pt;vertical-align: top;\" valign=\"top\" width=\"12.85930408472012%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: none;padding: 0in 5.4pt;height: 31.65pt;vertical-align: top;\" valign=\"top\" width=\"11.497730711043873%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 113.45pt;border: none;padding: 0in 5.4pt;height: 23.35pt;vertical-align: top;\" valign=\"top\" width=\"22.844175491679273%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;text-indent:6.0pt;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eDysrhythmia\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.85pt;border: none;padding: 0in 5.4pt;height: 23.35pt;vertical-align: top;\" valign=\"top\" width=\"14.22087745839637%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e1(0.3%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: none;padding: 0in 5.4pt;height: 23.35pt;vertical-align: top;\" valign=\"top\" width=\"11.497730711043873%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e2(0.6%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42.55pt;border: none;padding: 0in 5.4pt;height: 23.35pt;vertical-align: top;\" valign=\"top\" width=\"8.623298033282905%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0.613\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 21.25pt;border: none;padding: 0in 5.4pt;height: 23.35pt;vertical-align: top;\" valign=\"top\" width=\"4.236006051437216%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.85pt;border: none;padding: 0in 5.4pt;height: 23.35pt;vertical-align: top;\" valign=\"top\" width=\"14.22087745839637%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e1(0.4%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.8pt;border: none;padding: 0in 5.4pt;height: 23.35pt;vertical-align: top;\" valign=\"top\" width=\"12.85930408472012%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e1(0.4%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: none;padding: 0in 5.4pt;height: 23.35pt;vertical-align: top;\" valign=\"top\" width=\"11.497730711043873%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e1.000\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 113.45pt;border: none;padding: 0in 5.4pt;height: 23.35pt;vertical-align: top;\" valign=\"top\" width=\"22.844175491679273%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;text-indent:6.0pt;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eAngina in 24h\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.85pt;border: none;padding: 0in 5.4pt;height: 23.35pt;vertical-align: top;\" valign=\"top\" width=\"14.22087745839637%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e13(3.5%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: none;padding: 0in 5.4pt;height: 23.35pt;vertical-align: top;\" valign=\"top\" width=\"11.497730711043873%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e22(6.3%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42.55pt;border: none;padding: 0in 5.4pt;height: 23.35pt;vertical-align: top;\" valign=\"top\" width=\"8.623298033282905%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0.086\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 21.25pt;border: none;padding: 0in 5.4pt;height: 23.35pt;vertical-align: top;\" valign=\"top\" width=\"4.236006051437216%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.85pt;border: none;padding: 0in 5.4pt;height: 23.35pt;vertical-align: top;\" valign=\"top\" width=\"14.22087745839637%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e6(2.3%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.8pt;border: none;padding: 0in 5.4pt;height: 23.35pt;vertical-align: top;\" valign=\"top\" width=\"12.85930408472012%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e13(5.1%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: none;padding: 0in 5.4pt;height: 23.35pt;vertical-align: top;\" valign=\"top\" width=\"11.497730711043873%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0.159\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 113.45pt;border: none;padding: 0in 5.4pt;height: 23.35pt;vertical-align: top;\" valign=\"top\" width=\"22.844175491679273%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;text-indent:6.0pt;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003ePeriprocedural MI\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.85pt;border: none;padding: 0in 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42.55pt;border: none;padding: 0in 5.4pt;height: 23.35pt;vertical-align: top;\" valign=\"top\" width=\"8.623298033282905%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0.746\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 21.25pt;border: none;padding: 0in 5.4pt;height: 23.35pt;vertical-align: top;\" valign=\"top\" width=\"4.236006051437216%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n 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style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e3(0.9%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42.55pt;border: none;padding: 0in 5.4pt;height: 23.35pt;vertical-align: top;\" valign=\"top\" width=\"8.623298033282905%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0.359\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 21.25pt;border: none;padding: 0in 5.4pt;height: 23.35pt;vertical-align: top;\" valign=\"top\" width=\"4.236006051437216%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.85pt;border: none;padding: 0in 5.4pt;height: 23.35pt;vertical-align: top;\" valign=\"top\" width=\"14.22087745839637%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e1(0.4%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.8pt;border: none;padding: 0in 5.4pt;height: 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style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0(0.0%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.8pt;border: none;padding: 0in 5.4pt;height: 23.35pt;vertical-align: top;\" valign=\"top\" width=\"12.85930408472012%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e2(0.8%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: none;padding: 0in 5.4pt;height: 23.35pt;vertical-align: top;\" valign=\"top\" width=\"11.497730711043873%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0.499\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 113.45pt;border: none;padding: 0in 5.4pt;height: 23.35pt;vertical-align: top;\" valign=\"top\" width=\"22.844175491679273%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;text-indent:6.0pt;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eDissection\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.85pt;border: none;padding: 0in 5.4pt;height: 23.35pt;vertical-align: top;\" valign=\"top\" width=\"14.22087745839637%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e1(0.3%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: none;padding: 0in 5.4pt;height: 23.35pt;vertical-align: top;\" valign=\"top\" width=\"11.497730711043873%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e2(0.6%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42.55pt;border: none;padding: 0in 5.4pt;height: 23.35pt;vertical-align: top;\" valign=\"top\" width=\"8.623298033282905%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0.613\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 21.25pt;border: none;padding: 0in 5.4pt;height: 23.35pt;vertical-align: top;\" valign=\"top\" width=\"4.236006051437216%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n 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Roman\u0026quot;,serif;\"\u003e1(0.4%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: none;padding: 0in 5.4pt;height: 23.35pt;vertical-align: top;\" valign=\"top\" width=\"11.497730711043873%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e1.000\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 113.45pt;border: none;padding: 0in 5.4pt;height: 23.35pt;vertical-align: top;\" valign=\"top\" width=\"22.844175491679273%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;text-indent:6.0pt;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eAcute closure\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.85pt;border: none;padding: 0in 5.4pt;height: 23.35pt;vertical-align: top;\" valign=\"top\" width=\"14.22087745839637%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0(0.0%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: none;padding: 0in 5.4pt;height: 23.35pt;vertical-align: top;\" valign=\"top\" width=\"11.497730711043873%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e2(0.6%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42.55pt;border: none;padding: 0in 5.4pt;height: 23.35pt;vertical-align: top;\" valign=\"top\" width=\"8.623298033282905%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0.235\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 21.25pt;border: none;padding: 0in 5.4pt;height: 23.35pt;vertical-align: top;\" valign=\"top\" width=\"4.236006051437216%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.85pt;border: none;padding: 0in 5.4pt;height: 23.35pt;vertical-align: top;\" valign=\"top\" width=\"14.22087745839637%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0(0.0%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.8pt;border: none;padding: 0in 5.4pt;height: 23.35pt;vertical-align: top;\" valign=\"top\" width=\"12.85930408472012%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e1(0.4%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: none;padding: 0in 5.4pt;height: 23.35pt;vertical-align: top;\" valign=\"top\" width=\"11.497730711043873%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e1.000\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 113.45pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid black;padding: 0in 5.4pt;height: 23.35pt;vertical-align: top;\" valign=\"top\" width=\"22.844175491679273%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;text-indent:6.0pt;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eBleeding\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.85pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid black;padding: 0in 5.4pt;height: 23.35pt;vertical-align: top;\" valign=\"top\" width=\"14.22087745839637%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e2(0.5%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid black;padding: 0in 5.4pt;height: 23.35pt;vertical-align: top;\" valign=\"top\" width=\"11.497730711043873%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e5(1.4%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42.55pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid black;padding: 0in 5.4pt;height: 23.35pt;vertical-align: top;\" valign=\"top\" width=\"8.623298033282905%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0.273\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 21.25pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid black;padding: 0in 5.4pt;height: 23.35pt;vertical-align: top;\" valign=\"top\" width=\"4.236006051437216%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.85pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid black;padding: 0in 5.4pt;height: 23.35pt;vertical-align: top;\" valign=\"top\" width=\"14.22087745839637%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e2(0.8%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.8pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid black;padding: 0in 5.4pt;height: 23.35pt;vertical-align: top;\" valign=\"top\" width=\"12.85930408472012%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e4(1.6%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid black;padding: 0in 5.4pt;height: 23.35pt;vertical-align: top;\" valign=\"top\" width=\"11.497730711043873%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0.686\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003c/tbody\u003e\n\u003c/table\u003e\n\u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-size: 16px; font-family: \u0026quot;Times New Roman\u0026quot;, serif; background: white;\"\u003eAHF=acute heart failure; CABG=coronary artery bypass graft\u003c/span\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e; DM= diabetes mellitus; \u003cspan style=\"background: white;\"\u003eMI=\u003c/span\u003e\u003c/span\u003e\u003cspan style=\"font-size: 16px; font-family: \u0026quot;Times New Roman\u0026quot;, serif; background: white;\"\u003e\u0026nbsp;myocardial infarction;\u003c/span\u003e\u003c/span\u003e\u003cspan style=\"font-size: 16px; font-family: \u0026quot;Times New Roman\u0026quot;, serif; color: rgb(0, 0, 0); background: white;\"\u003e\u0026nbsp;PCI=percutaneous coronary intervention.\u003c/span\u003e\u003c/p\u003e\u003c/br\u003e\u003c/br\u003e\n\u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cstrong\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eTable 4\u003c/span\u003e\u003c/strong\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;Follow-up outcomes of\u0026nbsp;\u003c/span\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003epatients\u003c/span\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;with prior CABG (n=724)\u003c/span\u003e\u003c/p\u003e\n\u003ctable border=\"1\" cellpadding=\"0\" cellspacing=\"0\" style=\"margin-left:-44.25pt;border-collapse:collapse;border:none;\" width=\"699\"\u003e\n \u003ctbody\u003e\n \u003ctr\u003e\n \u003ctd rowspan=\"3\" style=\"width: 113.45pt;border-top: 1pt solid black;border-left: none;border-bottom: 1pt solid black;border-right: none;padding: 0in 5.4pt;height: 22.1pt;vertical-align: top;\" valign=\"top\" width=\"21.602288984263232%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:center;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;margin-top:12.0pt;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eOutcomes\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"3\" style=\"width: 198.45pt;border-top: 1pt solid black;border-left: none;border-bottom: 1pt solid black;border-right: none;padding: 0in 5.4pt;height: 22.1pt;vertical-align: top;\" valign=\"top\" width=\"37.911301859799714%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;text-indent:42.0pt;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eUnmatched\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd rowspan=\"2\" style=\"width: 21.25pt;border-right: none;border-bottom: none;border-left: none;border-image: initial;border-top: 1pt solid black;padding: 0in 5.4pt;height: 22.1pt;vertical-align: top;\" valign=\"top\" width=\"4.005722460658083%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;text-indent:1.0in;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"3\" style=\"width: 191.4pt;border-top: 1pt solid black;border-left: none;border-bottom: 1pt solid black;border-right: none;padding: 0in 5.4pt;height: 22.1pt;vertical-align: top;\" valign=\"top\" width=\"36.48068669527897%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;text-indent:1.0in;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eMatched\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 77.95pt;border: none;padding: 0in 5.4pt;height: 24.45pt;vertical-align: top;\" valign=\"top\" width=\"19.961612284069098%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eNo DM\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border: none;padding: 0in 5.4pt;height: 24.45pt;vertical-align: top;\" valign=\"top\" width=\"18.234165067178502%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;text-indent:12.0pt;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eDM\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd rowspan=\"2\" style=\"width: 49.6pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid black;padding: 0in 5.4pt;height: 24.45pt;vertical-align: top;\" valign=\"top\" width=\"12.667946257197697%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eP value\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border: none;padding: 0in 5.4pt;height: 24.45pt;vertical-align: top;\" valign=\"top\" width=\"18.234165067178502%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eNo DM\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.8pt;border: none;padding: 0in 5.4pt;height: 24.45pt;vertical-align: top;\" valign=\"top\" width=\"16.314779270633398%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;text-indent:12.0pt;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eDM\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd rowspan=\"2\" style=\"width: 56.7pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid black;padding: 0in 5.4pt;height: 24.45pt;vertical-align: top;\" valign=\"top\" width=\"14.587332053742802%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;margin-top:12.0pt;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eP value\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 77.95pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid black;padding: 0in 5.4pt;height: 17.55pt;vertical-align: top;\" valign=\"top\" width=\"25.552825552825553%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;text-indent:12.0pt;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003en=373\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid black;padding: 0in 5.4pt;height: 17.55pt;vertical-align: top;\" valign=\"top\" width=\"23.34152334152334%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003en=351\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 21.25pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid black;padding: 0in 5.4pt;height: 17.55pt;vertical-align: top;\" valign=\"top\" width=\"6.87960687960688%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;text-indent:12.0pt;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid black;padding: 0in 5.4pt;height: 17.55pt;vertical-align: top;\" valign=\"top\" width=\"23.34152334152334%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;text-indent:12.0pt;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003en=256\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.8pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid black;padding: 0in 5.4pt;height: 17.55pt;vertical-align: top;\" valign=\"top\" width=\"20.884520884520885%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003en=256\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 113.45pt;border: none;padding: 0in 5.4pt;height: 24.6pt;vertical-align: top;\" valign=\"top\" width=\"21.571428571428573%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eMACEs\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 77.95pt;border: none;padding: 0in 5.4pt;height: 24.6pt;vertical-align: top;\" valign=\"top\" width=\"14.857142857142858%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e114(30.6%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border: none;padding: 0in 5.4pt;height: 24.6pt;vertical-align: top;\" valign=\"top\" width=\"13.571428571428571%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e128(36.5%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 49.6pt;border: none;padding: 0in 5.4pt;height: 24.6pt;vertical-align: top;\" valign=\"top\" width=\"9.428571428571429%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0.055\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 21.25pt;border: none;padding: 0in 5.4pt;height: 24.6pt;vertical-align: top;\" valign=\"top\" width=\"4%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border: none;padding: 0in 5.4pt;height: 24.6pt;vertical-align: top;\" valign=\"top\" width=\"13.571428571428571%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e75(29.3%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.8pt;border: none;padding: 0in 5.4pt;height: 24.6pt;vertical-align: top;\" valign=\"top\" width=\"12.142857142857142%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e96(37.5%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: none;padding: 0in 5.4pt;height: 24.6pt;vertical-align: top;\" valign=\"top\" width=\"10.857142857142858%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0.051\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 113.45pt;border: none;padding: 0in 5.4pt;height: 24.6pt;vertical-align: top;\" valign=\"top\" width=\"21.571428571428573%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eCardiac death\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 77.95pt;border: none;padding: 0in 5.4pt;height: 24.6pt;vertical-align: top;\" valign=\"top\" width=\"14.857142857142858%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e18(4.8%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border: none;padding: 0in 5.4pt;height: 24.6pt;vertical-align: top;\" valign=\"top\" width=\"13.571428571428571%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e18(5.1%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 49.6pt;border: none;padding: 0in 5.4pt;height: 24.6pt;vertical-align: top;\" valign=\"top\" width=\"9.428571428571429%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0.695\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 21.25pt;border: none;padding: 0in 5.4pt;height: 24.6pt;vertical-align: top;\" valign=\"top\" width=\"4%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border: none;padding: 0in 5.4pt;height: 24.6pt;vertical-align: top;\" valign=\"top\" width=\"13.571428571428571%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e15(5.9%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.8pt;border: none;padding: 0in 5.4pt;height: 24.6pt;vertical-align: top;\" valign=\"top\" width=\"12.142857142857142%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e14(5.5%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: none;padding: 0in 5.4pt;height: 24.6pt;vertical-align: top;\" valign=\"top\" width=\"10.857142857142858%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0.871\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 113.45pt;border: none;padding: 0in 5.4pt;height: 24.6pt;vertical-align: top;\" valign=\"top\" width=\"21.571428571428573%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eMI\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 77.95pt;border: none;padding: 0in 5.4pt;height: 24.6pt;vertical-align: top;\" valign=\"top\" width=\"14.857142857142858%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e43(11.5%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border: none;padding: 0in 5.4pt;height: 24.6pt;vertical-align: top;\" valign=\"top\" width=\"13.571428571428571%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e62(17.7%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 49.6pt;border: none;padding: 0in 5.4pt;height: 24.6pt;vertical-align: top;\" valign=\"top\" width=\"9.428571428571429%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0.010\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 21.25pt;border: none;padding: 0in 5.4pt;height: 24.6pt;vertical-align: top;\" valign=\"top\" width=\"4%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border: none;padding: 0in 5.4pt;height: 24.6pt;vertical-align: top;\" valign=\"top\" width=\"13.571428571428571%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e33(12.9%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.8pt;border: none;padding: 0in 5.4pt;height: 24.6pt;vertical-align: top;\" valign=\"top\" width=\"12.142857142857142%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e47(18.4%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: none;padding: 0in 5.4pt;height: 24.6pt;vertical-align: top;\" valign=\"top\" width=\"10.857142857142858%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0.078\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 113.45pt;border: none;padding: 0in 5.4pt;height: 24.6pt;vertical-align: top;\" valign=\"top\" width=\"21.571428571428573%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eHF\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 77.95pt;border: none;padding: 0in 5.4pt;height: 24.6pt;vertical-align: top;\" valign=\"top\" width=\"14.857142857142858%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e39(10.5%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border: none;padding: 0in 5.4pt;height: 24.6pt;vertical-align: top;\" valign=\"top\" width=\"13.571428571428571%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e48(13.7%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 49.6pt;border: none;padding: 0in 5.4pt;height: 24.6pt;vertical-align: top;\" valign=\"top\" width=\"9.428571428571429%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0.095\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 21.25pt;border: none;padding: 0in 5.4pt;height: 24.6pt;vertical-align: top;\" valign=\"top\" width=\"4%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border: none;padding: 0in 5.4pt;height: 24.6pt;vertical-align: top;\" valign=\"top\" width=\"13.571428571428571%\"\u003e\n \u003cp 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\u003ctd style=\"width: 49.6pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid black;padding: 0in 5.4pt;height: 24.6pt;vertical-align: top;\" valign=\"top\" width=\"9.428571428571429%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0.593\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 21.25pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid black;padding: 0in 5.4pt;height: 24.6pt;vertical-align: top;\" valign=\"top\" width=\"4%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid black;padding: 0in 5.4pt;height: 24.6pt;vertical-align: top;\" valign=\"top\" width=\"13.571428571428571%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e47(18.4%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.8pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid black;padding: 0in 5.4pt;height: 24.6pt;vertical-align: top;\" valign=\"top\" width=\"12.142857142857142%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e50(19.5%)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid black;padding: 0in 5.4pt;height: 24.6pt;vertical-align: top;\" valign=\"top\" width=\"10.857142857142858%\"\u003e\n \u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:left;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003e0.747\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003c/tbody\u003e\n\u003c/table\u003e\n\u003cp style=\"margin:0in;margin-bottom:.0001pt;text-align:justify;font-size:14px;font-family:\u0026quot;Calibri\u0026quot;,sans-serif;\"\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;color:black;background:white;\"\u003eCABG=coronary artery bypass graft;\u0026nbsp;\u003c/span\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;\"\u003eDM= diabetes mellitus;\u0026nbsp;\u003c/span\u003e\u003cspan style=\"font-size:16px;font-family:\u0026quot;Times New Roman\u0026quot;,serif;color:black;background:white;\"\u003eHF=acute heart failure; MACEs= major adverse cardiac events; MI= myocardial infarction.\u003c/span\u003e\u003c/p\u003e"},{"header":"Supporting Information Figure Legends","content":"\u003cp\u003eFigure S1 Incidence of MACEs ( A), cardiac death (B), MI(C), HF(D) or revascularization (E) of patients with PCI in only NCA ( No DM vs DM) using the Kaplan-Meier method. P value was calculated by log-rank test. DM= diabetes mellitus, HF=acute heart failure, NCA= native coronary artery, MACEs= major adverse cardiac events, MI= myocardial infarction.\u003c/p\u003e\n\u003cp\u003e\u0026nbsp;\u003c/p\u003e\n\u003cp\u003eFigure S2 Incidence of MACEs ( A), cardiac death (B), MI(C), HF(D) or revascularization (E) of patients with PCI in NCA and graft ( No DM vs DM) using the Kaplan-Meier method. P value was calculated by log-rank test. DM= diabetes mellitus, HF=acute heart failure, NCA= native coronary artery, MACEs= major adverse cardiac events, MI= myocardial infarction.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u0026nbsp;\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eFigure S3 Incidence of MACEs ( A), cardiac death (B), MI(C), HF(D) or revascularization (E) of patients with first-generation DES PCI ( No DM vs DM) using the Kaplan-Meier method. P value was calculated by log-rank test. DM= diabetes mellitus, HF=acute heart failure, NCA= native coronary artery, MACEs= major adverse cardiac events, MI= myocardial infarction.\u003c/p\u003e\n\u003cp\u003e\u0026nbsp;\u003c/p\u003e\n\u003cp\u003eFigure S4 Incidence of MACEs ( A), cardiac death (B), MI(C), HF(D) or revascularization (E) of patients with second-generation DES PCI ( No DM vs DM) using the Kaplan-Meier method. P value was calculated by log-rank test. DM= diabetes mellitus, HF=acute heart failure, NCA= native coronary artery, MACEs= major adverse cardiac events, MI= myocardial infarction.\u003c/p\u003e"}],"fulltextSource":"","fullText":"","funders":[],"hasAdminPriorityOnWorkflow":false,"hasManuscriptDocX":true,"hasOptedInToPreprint":true,"hasPassedJournalQc":"","hasAnyPriority":false,"hideJournal":false,"highlight":"","institution":"","isAcceptedByJournal":true,"isAuthorSuppliedPdf":false,"isDeskRejected":"","isHiddenFromSearch":false,"isInQc":false,"isInWorkflow":false,"isPdf":false,"isPdfUpToDate":true,"isWithdrawnOrRetracted":false,"journal":{"display":true,"email":"[email protected]","identity":"bmc-cardiovascular-disorders","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":false,"externalIdentity":"bcar","sideBox":"Learn more about [BMC Cardiovascular Disorders](http://bmccardiovascdisord.biomedcentral.com/)","snPcode":"","submissionUrl":"https://www.editorialmanager.com/bcar/default.aspx","title":"BMC Cardiovascular Disorders","twitterHandle":"BMC_series","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"em","reportingPortfolio":"BMC Series","inReviewEnabled":true,"inReviewRevisionsEnabled":true},"keywords":"Percutaneous coronary intervention; Diabetic; Non-diabetic; Prior Coronary artery bypass grafting; Outcomes.","lastPublishedDoi":"10.21203/rs.2.15663/v3","lastPublishedDoiUrl":"https://doi.org/10.21203/rs.2.15663/v3","license":{"name":"CC BY 4.0","url":"https://creativecommons.org/licenses/by/4.0/"},"manuscriptAbstract":"Background: The target of this study was to explore the outcomes of percutaneous coronary intervention (PCI) in diabetic versus non-diabetic patients with prior coronary artery bypass grafting (CABG) surgery.\nMethods: Seven hundred and twenty four patients who had previously received CABG and had been treated using PCI combined with drug-eluting stents (DES) between 2009 and 2017 were selected for a retrospective study and allocated into either a diabetes mellitus (DM) or non-diabetes mellitus (No DM) group. A 1:1 propensity score-matched evaluation was conducted and risk adjusted for analysis. The primary outcomes were cardiac death, myocardial infarction, heart failure and revascularization, with a median follow-up duration of 5.13 years.\nResults: After matching, two-, 5- and 8-year event rate of overall major adverse cardiac events (MACEs) were found to be higher in the DM group (No DM vs DM:15.3%, 30.9%, 38.5% vs 19.8%, 37.8%, 52.2%, respectively), although no significant difference was found in the event rate of overall MACEs (hazard ratio [HR]: 1.35; 95% confidence interval [CI]: 1.00 to 1.83 for DM vs No DM; P=0.052), cardiac death (HR: 0.94; 95% CI: 0.45 to 1.95; P=0.871), MI (HR: 1.49; 95% CI: 0.95 to 2.32; P=0.080), HF (HR: 1.54; 95% CI: 0.90 to 2.63 for; P=0.120) or revascularization (HR: 1.07; 95% CI: 0.72 to 1.59; P=0.747). Subgroup analysis of PCI in only the NCA showed MACEs (adjusted HR: 1.13; 95% CI: 0.85 to 1.49 for DM vs No DM; P=0.325), cardiac death (adjusted HR: 0.85; 95% CI: 0.41 to 1.78 for DM vs No DM; P=0.781), MI (adjusted HR: 1.32; 95% CI: 0.84 to 2.01 for DM vs No DM; P=0.069), HF (adjusted HR: 1.41; 95% CI: 0.87 to 2.27 for DM vs No DM; P=0.211) or repeated revascularization (adjusted HR: 0.93; 95% CI: 0.64 to 1.37 for DM vs No DM; P=0.836).\nConclusions : Compared with non-diabetic patients with prior CABG, subsequent implantation of DES in the native coronary artery of diabetic patients resulted in apparently similar outcomes.\nTrial registration : This study was not registered in an open access database.\nKey Words: Percutaneous coronary intervention; Diabetic; Non-diabetic; Coronary artery bypass grafting.","manuscriptTitle":"Percutaneous Coronary Intervention in Diabetic versus Non-diabetic Patients with Prior Coronary Artery Bypass Grafting: A Propensity Score Matching Study","msid":"","msnumber":"","nonDraftVersions":[{"code":3,"date":"2020-02-18 14:03:09","doi":"10.21203/rs.2.15663/v3","editorialEvents":[{"type":"communityComments","content":0},{"type":"decision","content":"Accept","date":"2020-03-25T12:00:00+00:00","index":"","fulltext":""},{"type":"editorInvitedReview","content":"","date":"2020-03-11T12:00:00+00:00","index":2,"fulltext":"Recommendation: Accept without revision\nForm responses:\n---\n\nComments to Author:\n---\nThe authors have responded to all my feedback satisfactorily* Are the methods appropriate and well described?: **Yes**\n* Does the work include the necessary controls?: **Yes**\n* Are the conclusions drawn adequately supported by the data shown?: **Yes**\n* Are you able to assess any statistics in the manuscript or would you recommend an additional statistical review?: **I am able to assess the statistics**\n* Quality of written English: **Acceptable**\n* Declaration of competing interests: **I declare that I have no competing interests**\n* I agree to the open peer review policy of the journal. I understand that my name will be included on my report to the authors and, if the manuscript is accepted for publication, my named report including any attachments I upload will be posted on the website along with the authors' responses. I agree for my report to be made available under an Open Access Creative Commons CC-BY license (http://creativecommons.org/licenses/by/4.0/). I understand that any comments which I do not wish to be included in my named report can be included as confidential comments to the editors, which will not be published.: ** I agree to the open peer review policy of the journal**\n"},{"type":"editorInvitedReview","content":"","date":"2020-03-11T12:00:00+00:00","index":1,"fulltext":"Recommendation: Accept without revision\nForm responses:\n---\n\nComments to Author:\n---\nI am satisfied with the information provided by the authors in response to the comments and I believe that the article can be published* Are the methods appropriate and well described?: **Yes**\n* Does the work include the necessary controls?: **Yes**\n* Are the conclusions drawn adequately supported by the data shown?: **Yes**\n* Are you able to assess any statistics in the manuscript or would you recommend an additional statistical review?: **I am able to assess the statistics**\n* Quality of written English: **Acceptable**\n* Declaration of competing interests: **I declare that I have no competing interests**\n* I agree to the open peer review policy of the journal. I understand that my name will be included on my report to the authors and, if the manuscript is accepted for publication, my named report including any attachments I upload will be posted on the website along with the authors' responses. I agree for my report to be made available under an Open Access Creative Commons CC-BY license (http://creativecommons.org/licenses/by/4.0/). I understand that any comments which I do not wish to be included in my named report can be included as confidential comments to the editors, which will not be published.: ** I agree to the open peer review policy of the journal**\n"},{"type":"reviewersInvited","content":"","date":"2020-03-01T12:00:00+00:00","index":"","fulltext":""},{"type":"reviewerAgreed","content":"","date":"2020-03-01T12:00:00+00:00","index":1,"fulltext":""},{"type":"reviewerAgreed","content":"","date":"2020-03-01T12:00:00+00:00","index":2,"fulltext":""},{"type":"editorAssigned","content":"","date":"2020-02-16T12:00:00+00:00","index":"","fulltext":""},{"type":"checksComplete","content":"","date":"2020-02-15T12:00:00+00:00","index":"","fulltext":""},{"type":"editorInvited","content":"","date":"2020-02-15T12:00:00+00:00","index":"","fulltext":""}],"status":"published","journal":{"display":true,"email":"[email protected]","identity":"bmc-cardiovascular-disorders","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":false,"externalIdentity":"bcar","sideBox":"Learn more about [BMC Cardiovascular Disorders](http://bmccardiovascdisord.biomedcentral.com/)","snPcode":"","submissionUrl":"https://www.editorialmanager.com/bcar/default.aspx","title":"BMC Cardiovascular Disorders","twitterHandle":"BMC_series","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"em","reportingPortfolio":"BMC Series","inReviewEnabled":true,"inReviewRevisionsEnabled":true}},{"code":2,"date":"2019-12-19 17:58:26","doi":"10.21203/rs.2.15663/v2","editorialEvents":[{"type":"communityComments","content":0},{"type":"decision","content":"Major revision","date":"2020-02-11T12:00:00+00:00","index":"","fulltext":""},{"type":"editorInvitedReview","content":"","date":"2020-02-02T12:00:00+00:00","index":3,"fulltext":"Recommendation: Accept after discretionary revisions\nForm responses:\n---\n* Are the methods appropriate and well described?: **Yes**\n* Does the work include the necessary controls?: **Yes**\n* Are the conclusions drawn adequately supported by the data shown?: **Yes**\n* Are you able to assess any statistics in the manuscript or would you recommend an additional statistical review?: **I recommend additional statistical review**\n* Quality of written English: **Acceptable**\n* Declaration of competing interests: **'I declare that I have no competing interests'**\n\nComments to Author:\n---\nThe positive aspects of the study can be noted: a large sample size, a long observation period, and an assessment of a large number of factors in comparable samples.\nComments:\nThere is a clear tendency for the curves to differ in groups according to the MACE indicator, at the same time, the differences are statistically insignificant, but close to those (p = 0.052). The question arises - was there an analysis regarding the minimum group size to obtain meaniningful results?\nThe authors conduct subgroup analyzes to assess the impact of additional factors. This does not look like a good solution; it seems more justified to include these factors in the multivariate analysis model\n"},{"type":"editorInvitedReview","content":"","date":"2020-01-31T12:00:00+00:00","index":2,"fulltext":"Recommendation: Accept after minor essential revisions\nForm responses:\n---\n* Are the methods appropriate and well described?: **Yes**\n* Does the work include the necessary controls?: **Yes**\n* Are the conclusions drawn adequately supported by the data shown?: **Yes**\n* Are you able to assess any statistics in the manuscript or would you recommend an additional statistical review?: **I am able to assess the statistics**\n* Quality of written English: **Needs some language corrections before being published**\n* Declaration of competing interests: **I declare that I have no competing interests**\n\nComments to Author:\n---\n1) Please add this citation at the end of first paragraph of background section: Shah R, Yang Y, Bentley JP, Banahan III BF. Comparative effectiveness of coronary artery bypass grafting (CABG) surgery and percutaneous coronary intervention (PCI) in elderly patients with diabetes. Current medical research and opinion. 2016 Nov 1;32(11):1891-8.\n2) Define what stands as baseline, is this before CABG or before PCI?\n3) Also, when was presence of DM calculated (before or after PCI)?\n4) What if a non-DM patient was diagnosed as DM during study follow-up?\n5) Was death accounted for as a competing risk in any of the non-death related models?\n6) The section on procedural complications refers to complications post CABG or PCI?\n7) did you do PS matching for your sub-group analysis? if not then state in limitations\n8) did you include the date of PCI as a matching variable? what was the caliper width for PS matching?"},{"type":"editorInvitedReview","content":"","date":"2020-01-21T12:00:00+00:00","index":1,"fulltext":"Recommendation: Accept without revision\nForm responses:\n---\n* Are the methods appropriate and well described?: **Yes**\n* Does the work include the necessary controls?: **Yes**\n* Are the conclusions drawn adequately supported by the data shown?: **Yes**\n* Are you able to assess any statistics in the manuscript or would you recommend an additional statistical review?: **I am able to assess the statistics**\n* Quality of written English: **Acceptable**\n* Declaration of competing interests: **I declare that I have no competing interests.**\n\nComments to Author:\n---\nIn this manuscript, the authors investigated the efficacy of drug-eluting stents in patients with prior CABG on long-term clinical outcomes through propensity score matching analysis. The data analysis methods used in this study are appropriate and the results support their conclusion.\nThe author explained the questions asked by the reviewers and modified and supplemented the article. I think the manuscript can be accepted by the journal."},{"type":"reviewerAgreed","content":"","date":"2020-01-20T12:00:00+00:00","index":3,"fulltext":""},{"type":"reviewerAgreed","content":"","date":"2020-01-16T12:00:00+00:00","index":2,"fulltext":""},{"type":"reviewersInvited","content":"","date":"2020-01-15T12:00:00+00:00","index":"","fulltext":""},{"type":"reviewerAgreed","content":"","date":"2020-01-15T12:00:00+00:00","index":1,"fulltext":""},{"type":"editorAssigned","content":"","date":"2019-12-16T12:00:00+00:00","index":"","fulltext":""},{"type":"checksComplete","content":"","date":"2019-12-15T12:00:00+00:00","index":"","fulltext":""},{"type":"editorInvited","content":"","date":"2019-12-15T12:00:00+00:00","index":"","fulltext":""}],"status":"published","journal":{"display":true,"email":"[email protected]","identity":"bmc-cardiovascular-disorders","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":false,"externalIdentity":"bcar","sideBox":"Learn more about [BMC Cardiovascular Disorders](http://bmccardiovascdisord.biomedcentral.com/)","snPcode":"","submissionUrl":"https://www.editorialmanager.com/bcar/default.aspx","title":"BMC Cardiovascular Disorders","twitterHandle":"BMC_series","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"em","reportingPortfolio":"BMC Series","inReviewEnabled":true,"inReviewRevisionsEnabled":true}},{"code":1,"date":"2019-10-07 21:27:29","doi":"10.21203/rs.2.15663/v1","editorialEvents":[{"type":"communityComments","content":0},{"type":"decision","content":"Major revision","date":"2019-11-26T12:00:00+00:00","index":"","fulltext":""},{"type":"editorInvitedReview","content":"","date":"2019-10-25T12:00:00+00:00","index":2,"fulltext":"Recommendation: Major revisions required\nForm responses:\n---\n* Are the methods appropriate and well described?: **No**\n* Does the work include the necessary controls?: **Yes**\n* Are the conclusions drawn adequately supported by the data shown?: **No**\n* Are you able to assess any statistics in the manuscript or would you recommend an additional statistical review?: **I am able to assess the statistics**\n* Quality of written English: **Acceptable**\n* Declaration of competing interests: **I declare that I have no competing interests**\n\nComments to Author:\n---\nWe have read with interest the article by Ma X, et al entitled \"Percutaneous coronary intervention in diabetic versus non-diabetic patients with prior coronary artery bypass grafting: a propensity score matching study\". In this article, the authors conducted the propensity score matching analysis to evaluate the efficacy of drug-eluting stents (DES) in patients with prior CABG on long-term clinical outcomes. This is a very important issue in the real world clinical setting because DES use for patients with prior CABG has been dramatically increased. However, I have several comments as follows:\n\nMajor Comments\n1. The authors concluded that DES use in native coronary artery（NCA) in diabetic patients with prior CABG compared with non-diabetes. However, the results showed the significant difference between two groups (Kaplan Meier curve after matching; Figure 4A) and tend to be higher risk in diabetic patients (HR 1.35, 95% CI 1.00-183, p=0.052). We think it is difficult to draw the conclusion from this study.\n2. In this study, both 1st and 2nd generation DES were used. First generation DES had higher risk of late catch-up events including stent thrombosis than 2nd generation DES. We think the effect of the result was different between 1st and 2nd generationi DES, it may be better to perform stratified analysis.\n3. The authors mentioned 12% of patients treated with DES not only in NCA but also graft disease. PCI for graft disease, especially in SVG graft, is still challenging in clinical practice and pathophysiologically different issue from native coronary artery disease. The author should exclude this population if the authors would like to use the phrase \"subsequent implantation of DES in the native coronary artery\" in conclusion.\n4. Achievement of the complete revascularization with combination of CABG and PCI may reduce the risk of subsequent events. We would like to know the rate of complete revascularization and the impact on clinical outcomes. The authors should discuss this important issue.\n\nMinor comments\n1. Please be prepared to move figures to files with a high resolution.\n"},{"type":"reviewerAgreed","content":"","date":"2019-10-23T12:00:00+00:00","index":2,"fulltext":""},{"type":"checksComplete","content":"","date":"2019-09-30T12:00:00+00:00","index":"","fulltext":""},{"type":"editorInvitedReview","content":"","date":"2019-08-30T12:00:00+00:00","index":1,"fulltext":"Recommendation: Major revisions required\nForm responses:\n---\n* Are the methods appropriate and well described?: **Yes**\n* Does the work include the necessary controls?: **Yes**\n* Are the conclusions drawn adequately supported by the data shown?: **Unable to assess**\n* Are you able to assess any statistics in the manuscript or would you recommend an additional statistical review?: **I recommend additional statistical review**\n* Quality of written English: **Acceptable**\n* Declaration of competing interests: **I declare that I have no competing interest's below**\n\nComments to Author:\n---\nThe authors presented their data comparing the revascularization outcomes in DM vs non DM in adequate sample size.They concluded that in CABG, subsequent implantation of DES in the native coronary artery\nof diabetic patients resulted in apparently similar outcomes. This paper is well written.\nFew comments:\nCan the author provide syntax score for the sample size?\n"},{"type":"reviewerAgreed","content":"","date":"2019-08-25T12:00:00+00:00","index":1,"fulltext":""},{"type":"reviewersInvited","content":"","date":"2019-08-24T12:00:00+00:00","index":"","fulltext":""},{"type":"editorAssigned","content":"","date":"2019-08-23T12:00:00+00:00","index":"","fulltext":""},{"type":"submitted","content":"","date":"2019-08-22T12:00:00+00:00","index":"","fulltext":""},{"type":"editorInvited","content":"","date":"2019-08-22T12:00:00+00:00","index":"","fulltext":""}],"status":"published","journal":{"display":true,"email":"[email protected]","identity":"bmc-cardiovascular-disorders","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":false,"externalIdentity":"bcar","sideBox":"Learn more about [BMC Cardiovascular Disorders](http://bmccardiovascdisord.biomedcentral.com/)","snPcode":"","submissionUrl":"https://www.editorialmanager.com/bcar/default.aspx","title":"BMC Cardiovascular Disorders","twitterHandle":"BMC_series","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"em","reportingPortfolio":"BMC Series","inReviewEnabled":true,"inReviewRevisionsEnabled":true}}],"origin":"","ownerIdentity":"cc15e4ce-a3d7-417a-bfcb-c852a5585b5f","owner":[],"postedDate":"February 18th, 2020","published":true,"recentEditorialEvents":[],"rejectedJournal":[],"revision":"","amendment":"","status":"published-in-journal","subjectAreas":[{"id":44192,"name":"Cardiac \u0026 Cardiovascular Systems"},{"id":44193,"name":"Cardiothoracic Surgery"}],"tags":[],"updatedAt":"2021-09-27T18:27:16+00:00","versionOfRecord":{"articleIdentity":"rs-6325","link":"https://doi.org/10.1186/s12872-020-01447-8","journal":{"identity":"bmc-cardiovascular-disorders","isVorOnly":false,"title":"BMC Cardiovascular Disorders"},"publishedOn":"2020-04-06 18:17:44","publishedOnDateReadable":"April 6th, 2020"},"versionCreatedAt":"2020-02-18 14:03:09","video":"","vorDoi":"10.1186/s12872-020-01447-8","vorDoiUrl":"https://doi.org/10.1186/s12872-020-01447-8","workflowStages":[]},"version":"v3","identity":"rs-6325","journalConfig":"researchsquare"},"__N_SSP":true},"page":"/article/[identity]/[[...version]]","query":{"identity":"rs-6325","version":["v3"]},"buildId":"wLkW0s4AflPzk-lpfg-fK","isFallback":false,"isExperimentalCompile":false,"dynamicIds":[84888],"gssp":true,"scriptLoader":[]}