Expression and epigenetic change of the AR and FSHR genes in the granulosa cells of endometriosis patients

This dissertation investigates the expression levels and epigenetic modifications of androgen receptor (AR) and follicle-stimulating hormone receptor (FSHR) genes within granulosa cells obtained from patients with endometriosis. The research focuses on analyzing promoter region methylation patterns to determine how these epigenetic changes influence gene expression in the context of the disease. By comparing these molecular markers, the study aims to elucidate potential mechanisms linking hormonal signaling abnormalities to the pathophysiology of endometriotic lesions. This paper is centrally about endometriosis — specifically examining genetic and epigenetic factors in granulosa cells associated with the condition.

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