LIPIDOMIC PROFILING AS A TOOL FOR EARLY DETECTION AND RECURRENCE PREDICTION OF OVARIAN ENDOMETRIOSIS AFTER SURGERY

Y.M. Kuzieva, D.D. Saidjalilova
2026 · doi:10.5281/zenodo.22953076 · W7214341228
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This research investigates lipidomic profiling as a potential tool for the early detection and prediction of ovarian endometriosis recurrence following surgical intervention.

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The study investigates lipidomic profiling as a potential biomarker strategy for the early detection and recurrence prediction of ovarian endometriosis following surgical intervention. It addresses the clinical challenge of delayed diagnosis, which averages six to seven years, and the significant issue of postoperative disease recurrence that necessitates better predictive tools. By analyzing lipid profiles, the research aims to identify specific metabolic signatures associated with ovarian endometriosis to improve monitoring after surgery. This paper is centrally about endometriosis — specifically focusing on the use of lipidomics for managing ovarian endometriosis recurrence after surgical treatment.

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Abstract

Ovarian endometriosis (OE) remains one of the most challenging gynecological disorders due to delayed diagnosis and a high rate of postoperative recurrence. Initial symptoms, such as chronic pelvic pain and dysmenorrhea, commonly appear during adolescence or early reproductive age. However, according to the World Endometriosis Society, the average diagnostic delay worldwide is approximately 6–7 years from the onset of symptoms. Recurrence after surgical treatment remains a significant clinical problem, necessitating improved predictive and preventive strategies.
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LIPIDOMIC PROFILING AS A TOOL FOR EARLY DETECTION AND RECURRENCE PREDICTION OF OVARIAN ENDOMETRIOSIS AFTER SURGERY Authors/Creators Description Ovarian endometriosis (OE) remains one of the most challenging gynecological disorders due to delayed diagnosis and a high rate of postoperative recurrence. Initial symptoms, such as chronic pelvic pain and dysmenorrhea, commonly appear during adolescence or early reproductive age. However, according to the World Endometriosis Society, the average diagnostic delay worldwide is approximately 6–7 years from the onset of symptoms. Recurrence after surgical treatment remains a significant clinical problem, necessitating improved predictive and preventive strategies. Files SSPME 1114.pdf Files (298.0 kB) | Name | Size | Download all | |---|---|---| | md5:66a9a829fd6c11afe1817e363e262d38 | 298.0 kB | Preview Download |

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