ENDOMETRIOSIS INTESTINAL
Endometriosis, affecting 15% of premenopausal women, is characterized by endometrial tissue outside the uterus, most commonly implanting on abdomino-pelvic organs with the intestine being the most frequent extragenital site.
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The paper presents a case report of a 45-year-old woman with prior endometriosis who underwent screening colonoscopy for colorectal cancer risk, during which a 3–4 mm sessile polyp in the sigmoid colon was removed. Histopathology showed glands lined by endometrioid epithelium without atypia surrounded by endometrioid stroma, with cytokeratin 7 and CD10 positivity, while overlying colonic mucosa was preserved. The authors describe that intestinal endometriosis most commonly affects the rectosigmoid in the late 30s and typically involves the serosa, with nonspecific symptoms such as cyclic colicky abdominal pain, rectal bleeding, or obstruction, and emphasizes that diagnosis is anatomic-pathological with differentiation from conditions including IBD, ischemic colitis, diverticulitis, IBS, and colorectal cancer. This paper is centrally about endometriosis — it reports and characterizes intestinal endometriosis found on colonoscopy and highlights diagnostic considerations for gastrointestinal symptoms in reproductive-age women.
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- last seen: 2026-06-10T17:14:06.276822+00:00